Lumbar segmental mobility disorders: comparison of two methods of defining abnormal displacement kinematics in a cohort of patients with non-specific mechanical low back pain

Journal ArticleBackground: Lumbar segmental rigidity (LSR) and lumbar segmental instability (LSI) are believed to be associated with low back pain (LBP), and identification of these disorders is believed to be useful for directing intervention choices. Previous studies have focussed on lumbar segmental rotation and translation, but have used widely varying methodologies. Cut-off points for the diagnosis of LSR & LSI are largely arbitrary. Prevalence of these lumbar segmental mobility disorders (LSMDs) in a non-surgical, primary care LBP population has not been established. Methods: A cohort of 138 consecutive patients with recurrent or chronic low back pain (RCLBP) were recruited in this prospective, pragmatic, multi-centre study. Consenting patients completed pain and disability rating instruments, and were referred for flexion-extension radiographs. Sagittal angular rotation and sagittal translation of each lumbar spinal motion segment was measured from the radiographs, and compared to a reference range derived from a study of 30 asymptomatic volunteers. In order to define reference intervals for normal motion, and define LSR and LSI, we approached the kinematic data using two different models. The first model used a conventional Gaussian definition, with motion beyond two standard deviations (2sd) from the reference mean at each segment considered diagnostic of rotational LSMD and translational LSMD. The second model used a novel normalised within-subjects approach, based on mean normalised contributionto-total-lumbar-motion. An LSMD was then defined as present in any segment that contributed motion beyond 2sd from the reference mean contribution-to-normalised-total-lumbar-motion. We described reference intervals for normal segmental mobility, prevalence of LSMDs under each model, and the association of LSMDs with pain and disability. Results: With the exception of the conventional Gaussian definition of rotational LSI, LSMDs were found in statistically significant prevalences in patients with RCLBP. Prevalences at both the segmental and patient level were generally higher using the normalised within-subjects model (2.8 to 16.8% of segments; 23.3 to 35.5% of individuals) compared to the conventional Gaussian model (0 to 15.8%; 4.7 to 19.6%). LSMDs are associated with presence of LBP, however LSMDs do not appear to be strongly associated with higher levels of pain or disability compared to other forms of non-specific LBP. Conclusion: LSMDs are a valid means of defining sub-groups within non-specific LBP, in a conservative care population of patients with RCLBP. Prevalence was higher using the normalised within-subjects contribution-to-total-lumbar-motion approach

The Relationship between Change of Direction Speed in the Frontal Plane, Power, Reactive Strength, and Strength

International Journal of Exercise Science 7(4) : 260-270, 2014. Change-of-direction speed (CODS) is an important quality to performance in multi-direction sports. The relationship between CODS in the frontal plane and power, strength, and reactive strength is largely unstudied. Twenty-three male college students participated in this study. The study used a Pearson’s product-moment correlation to measure the relationship between CODS, power, strength, and reactive strength. A lateral shuffle test was used as the measure of CODS. A lateral hop for distance was used as the measure of power in the frontal plane. A countermovement vertical jump test was used as the measure of power in the sagittal plane. A depth jump was used as the measure of reactive strength in the sagittal plane. A 3RM squat test was used as the measure of strength. There was a moderate relationship between the lateral shuffle test and the lateral hop (r =.541, p = .008 and r =.567, p = .005), but no significant relationships with the countermovement vertical jump, depth jump, or squat test. These results suggest that power should be trained in all planes to improve CODS performance in multi-direction sports, and that CODS should be trained in its sport-specific context

The effects of frontal- and sagittal-plane plyometrics on change-of-direction speed and power in adolescent female basketball players

Plyometrics is a popular training modality for basketball players to improve power and change-of-direction speed. Most plyometric training has used sagittal-plane exercises, but improvements in change-of-direction speed have been greater in multi direction programs. Purpose: To determine the benefits of a 6-wk frontal-plane plyometric (FPP) training program compared with a 6-wk sagittal-plane plyometric (SPP) training program with regard to power and change-of-direction speed. Methods: Fourteen female varsity high school basketball players participated in the study. Multiple 2 x 2 repeated-measures ANOVAs were used to determine differences for the FPP and SPP groups from preintervention to postintervention on 4 tests of power and 2 tests of change-of-direction speed. Results: There was a group main effect for time in all 6 tests. There was a significant group x time interaction effect in 3 of the 6 tests. The SPP improved performance of the countermovement vertical jump more than the FPP, whereas the FPP improved performance of the lateral hop (left) and lateral-shuffle test (left) more than the SPP. The standing long jump, lateral hop (right), and lateral-shuffle test (right) did not show a significant interaction effect. Conclusions: These results suggest that basketball players should incorporate plyometric training in all planes to improve power and change-of-direction speed

Comparison of physical activity in small-sided basketball games versus full-sided games

Organized youth sports leagues attempt to meet many goals. Three primary needs for a youth sports league are to meet the participants' desires, provide quality learning experiences, and develop the competencies needed for continued participation. Possessing the ball, shooting more, and being more involved with a team's offense lead to more enjoyment and feelings of competence. Therefore, increasing the involvement of each player through more ball contacts should be a goal of youth sports leagues. Twelve male basketball players (age=15) from one high-school basketball team participated in this study. This study used paired t-tests to examine the differences between three-on-three basketball games and five-on-five basketball games that lasted for eight minutes in terms of average heart rate, moderate to vigorous intensity physical activity, vigorous intensity activity, and ball contacts. There were no significant differences between average heart rate, moderate-to-vigorous intensity activity, or vigorous intensity activity in the two conditions, but there were significantly more ball contacts on average in the three-on-three games. These results suggest that three-on-three leagues may be an appropriate sport for the initial exposure to basketball for youth players

Lumbar segmental mobility disorders: comparison of two methods of defining abnormal displacement kinematics in a cohort of patients with non-specific mechanical low back pain

BACKGROUND: Lumbar segmental rigidity (LSR) and lumbar segmental instability (LSI) are believed to be associated with low back pain (LBP), and identification of these disorders is believed to be useful for directing intervention choices. Previous studies have focussed on lumbar segmental rotation and translation, but have used widely varying methodologies. Cut-off points for the diagnosis of LSR & LSI are largely arbitrary. Prevalence of these lumbar segmental mobility disorders (LSMDs) in a non-surgical, primary care LBP population has not been established. METHODS: A cohort of 138 consecutive patients with recurrent or chronic low back pain (RCLBP) were recruited in this prospective, pragmatic, multi-centre study. Consenting patients completed pain and disability rating instruments, and were referred for flexion-extension radiographs. Sagittal angular rotation and sagittal translation of each lumbar spinal motion segment was measured from the radiographs, and compared to a reference range derived from a study of 30 asymptomatic volunteers. In order to define reference intervals for normal motion, and define LSR and LSI, we approached the kinematic data using two different models. The first model used a conventional Gaussian definition, with motion beyond two standard deviations (2sd) from the reference mean at each segment considered diagnostic of rotational LSMD and translational LSMD. The second model used a novel normalised within-subjects approach, based on mean normalised contribution-to-total-lumbar-motion. An LSMD was then defined as present in any segment that contributed motion beyond 2sd from the reference mean contribution-to-normalised-total-lumbar-motion. We described reference intervals for normal segmental mobility, prevalence of LSMDs under each model, and the association of LSMDs with pain and disability. RESULTS: With the exception of the conventional Gaussian definition of rotational LSI, LSMDs were found in statistically significant prevalences in patients with RCLBP. Prevalences at both the segmental and patient level were generally higher using the normalised within-subjects model (2.8 to 16.8% of segments; 23.3 to 35.5% of individuals) compared to the conventional Gaussian model (0 to 15.8%; 4.7 to 19.6%). LSMDs are associated with presence of LBP, however LSMDs do not appear to be strongly associated with higher levels of pain or disability compared to other forms of non-specific LBP. CONCLUSION: LSMDs are a valid means of defining sub-groups within non-specific LBP, in a conservative care population of patients with RCLBP. Prevalence was higher using the normalised within-subjects contribution-to-total-lumbar-motion approach

Avian Genetic Resources at Risk: An Assessment and Proposal for Conservation of Genetic Stocks in the USA and Canada

Genetic diversity, in both wild and domestic species, is a limited resource worth preserving for future generations (Oldfield 1984; Alderson 1990; FAO 1992; NRC 1993; Bixby et al. 1994). While many strong advocates promote the conservation of wild species, fewer are aware of the increasing loss of biodiversity in our major food species, particularly among domestic birds. Fortunately, breed conservation organizations have already made some progress in encouraging hobbyists and small-scale farmers in their role as conservators of unique and historically important breeds (Bixby et al. 1994), particularly the less common chicken and turkey breeds (Crawford and Christman 1992). These two species are considered more at-risk than most other livestock species (e.g., cow, pig, sheep, goat, or horse) due to recent and extraordinarily rapid expansion of the commercial poultry industry

A2BR Adenosine Receptor Modulates Sweet Taste in Circumvallate Taste Buds

In response to taste stimulation, taste buds release ATP, which activates ionotropic ATP receptors (P2X2/P2X3) on taste nerves as well as metabotropic (P2Y) purinergic receptors on taste bud cells. The action of the extracellular ATP is terminated by ectonucleotidases, ultimately generating adenosine, which itself can activate one or more G-protein coupled adenosine receptors: A1, A2A, A2B, and A3. Here we investigated the expression of adenosine receptors in mouse taste buds at both the nucleotide and protein expression levels. Of the adenosine receptors, only A2B receptor (A2BR) is expressed specifically in taste epithelia. Further, A2BR is expressed abundantly only in a subset of taste bud cells of posterior (circumvallate, foliate), but not anterior (fungiform, palate) taste fields in mice. Analysis of double-labeled tissue indicates that A2BR occurs on Type II taste bud cells that also express Gα14, which is present only in sweet-sensitive taste cells of the foliate and circumvallate papillae. Glossopharyngeal nerve recordings from A2BR knockout mice show significantly reduced responses to both sucrose and synthetic sweeteners, but normal responses to tastants representing other qualities. Thus, our study identified a novel regulator of sweet taste, the A2BR, which functions to potentiate sweet responses in posterior lingual taste fields

A Human Lung Xenograft Mouse Model of Nipah Virus Infection

Nipah virus (NiV) is a member of the genus Henipavirus (family Paramyxoviridae) that causes severe and often lethal respiratory illness and encephalitis in humans with high mortality rates (up to 92%). NiV can cause Acute Lung Injury (ALI) in humans, and human-to-human transmission has been observed in recent outbreaks of NiV. While the exact route of transmission to humans is not known, we have previously shown that NiV can efficiently infect human respiratory epithelial cells. The molecu