Demi-linear Analysis III---Demi-distributions with Compact Support

A series of detailed quantitative results is established for the family of demi-distributions which is a large extension of the family of usual distributions

High-efficient deep learning-based DTI reconstruction with flexible diffusion gradient encoding scheme

Purpose: To develop and evaluate a novel dynamic-convolution-based method called FlexDTI for high-efficient diffusion tensor reconstruction with flexible diffusion encoding gradient schemes. Methods: FlexDTI was developed to achieve high-quality DTI parametric mapping with flexible number and directions of diffusion encoding gradients. The proposed method used dynamic convolution kernels to embed diffusion gradient direction information into feature maps of the corresponding diffusion signal. Besides, our method realized the generalization of a flexible number of diffusion gradient directions by setting the maximum number of input channels of the network. The network was trained and tested using data sets from the Human Connectome Project and a local hospital. Results from FlexDTI and other advanced tensor parameter estimation methods were compared. Results: Compared to other methods, FlexDTI successfully achieves high-quality diffusion tensor-derived variables even if the number and directions of diffusion encoding gradients are variable. It increases peak signal-to-noise ratio (PSNR) by about 10 dB on Fractional Anisotropy (FA) and Mean Diffusivity (MD), compared with the state-of-the-art deep learning method with flexible diffusion encoding gradient schemes. Conclusion: FlexDTI can well learn diffusion gradient direction information to achieve generalized DTI reconstruction with flexible diffusion gradient schemes. Both flexibility and reconstruction quality can be taken into account in this network.Comment: 11 pages,6 figures,3 table

Extended dominating set in ad hoc networks using cooperative communication

Abstract. We propose a notion of extended dominating set whereby each node in an ad hoc network is covered by either a dominating neighbor or several 2-hop dominating neighbors. This work is motivated by cooperative communication in ad hoc networks where transmitting independent copies of a packet generates diversity and combats the effects of fading. In this paper we propose several efficient heuristic algorithms for constructing a small extended dominating set

Cultivation practices, maize and soybean productivity and soil properties on fragile slopes in Yunnan Province, China

Sustainable agriculture in China is highly threatened by rapid urbanization, land degradation and high population pressure. Yunnan Province, south-west China, is 94% mountainous and lacks flat land. Food shortages and inappropriate cultivation have led to intensive cultivation of steep, marginal and fragile land and have increased soil erosion. To curb this situation and assist with poverty alleviation, it is crucial to develop more productive and sustainable cropping systems. An experiment was conducted on sloping areas from 1999 to 2001 in Wang Jia Catchment, Yunnan Province. The project aim was to evaluate the effects of five selected cultivation practices on maize productivity and soil properties. The treatments were: (1) downslope cultivation without mulch, (2) contour cultivation without mulch, (3) contour cultivation with polythene mulch, (4) contour cultivation with polythene and wheat straw mulch (Integrated Contour with Plastic and Straw Mulch Treatment, INCOPLAST) and (5) contour cultivation with polythene mulch and intercropping, wide and narrow row spacing, with soybean in wide row spacing. Crop growth parameters and soil physical properties were measured throughout the cropping seasons. Considering three years data, contour cultivation with polythene mulch generally increased soil temperature by a mean of 1-2°C. The polythene retained considerably more soil moisture during dry weather. However, during wet weather, polythene prevented rainfall directly falling on the soil, which led to less soil moisture content. The soil temperature and moisture regimes under polythene mulch made plants grow faster and canopies develop well, leading to higher final yields. The benefit of polythene was 33-54% more yield than downslope cultivation without mulch treatment, over three seasons. Contour cultivation plus polythene and straw mulch retained significantly higher soil moisture levels. The yield of this treatment in 1999 was ranked second, but in 2000 it had the highest yield and in 2001 it was also more effective than contour cultivation with polythene mulch treatment. Contour cultivation with polythene mulch and intercropping improved maize yield. The soybean harvest also contributed to net income, the crop had a similar function to straw mulch and increased N availability. Contour cultivation increased yields over the range 7.2-11.2% over three seasons compared with downslope cultivation, equivalent to ~500-1000 kg per hectare more grain produced. There were few clear trends in soil properties over the 1999-2001 period. However, N concentrations increased in the contour cultivation with polythene mulch and intercropping treatment. Both contour cultivation with polythene and straw mulch and contour cultivation with polythene mulch and intercropping gave apparent increases in total K, probably resulting from both decayed straw and decomposed soybean leaves. In terms of simple cost-benefit evaluation, downslope cultivation had the lowest input and output, while contour cultivation had a similar input, but a higher output. Contour cultivation with polythene had the highest net return. Contour cultivation with polythene and straw had a high output but did not give a higher net return than contour cultivation with polythene. Contour cultivation with polythene mulch and intercropping generally had the highest input and output and could give a higher net return than contour cultivation with polythene when the soybean harvest was successful, but over three years this treatment had the greatest risk from crop failure. It is recommended that replacing downslope cultivation with contour cultivation can increase crop yields and this simple action could contribute to the development of more sustainable cropping systems in Yunnan. Polythene mulch achieved higher maize yields but its environmental impact requires further study. It is considered that contour cultivation with polythene and straw mulch or soybean intercropping could contribute towards more productive and sustainable cropping systems where soil conservation is high priority. The technique could assist with long-term soil, water and nutrient conservation and improved crop productivity.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Enhanced drug loading capacity of polypyrrole nanowire network for confrolled drug release

For a conducting polymer (CP) based drug release system, drug loading is often accomplished by a doping process, in which drug is incorporated into polymer as dopant. Therefore, the drug loading capacity is relatively low and the range of drugs can be loaded is limited. In the present work, a polypyrrole (PPy) nanowire network is prepared by an electrochemical method and it is found that the micro- and nano- gaps among the individual nanowires of the PPy nanowire network can be used as reservoir to store drugs. Therefore, the drug loading capacity is dependent on the volume of these micro- and nano-vacancies, instead of the doping level. The range of loaded drugs also can be theoretically extended to any drugs, instead of only charged dopants. In fact, it is confirmed here that both hydrophilic and lipophilic drugs can be loaded into the micro- and nano-gaps due to the amphilicity of the PPy nanowire network. As a result, both drug loading capacity and the range of drugs can be loaded are significantly improved. After being covered with a protective PPy film, controlled drug release from the prepared system is achieved by electrical stimulation (cyclic voltammetry, CV) and the amount of drug released can be controlled by changing the scan rate of CV and the thickness of the protective PPy film.Web of Scienc

Function of Chick Subcutaneous Adipose Tissue During the Embryonic and Posthatch Period

Since excess abdominal fat is one of the main problems in the broiler industry for the development of modern broiler and layer industry, the importance of subcutaneous adipose tissue has been neglected. However, chick subcutaneous adipose tissue appeared earlier than abdominal adipose tissue and more than abdominal adipose tissue. Despite a wealth of data, detailed information is lacking about the development and function of chick subcutaneous adipose tissue during the embryonic and posthatch period. Therefore, the objective of the current study was to determine the developmental changes of adipocyte differentiation, lipid synthesis, lipolysis, fatty acid β-oxidation, and lipid contents from E12 to D9.5. The results showed that subcutaneous adipose tissue was another important energy supply tissue during the posthatch period. In this stage, the mitochondrial copy number and fatty acid β-oxidation level significantly increased. It revealed that chick subcutaneous adipose tissue not only has the function of energy supply by lipidolysis but also performs the same function as brown adipose tissue to some extent, despite that the brown adipose tissue does not exist in birds. In addition, this finding improved the theory of energy supply in the embryonic and posthatch period and might provide theoretical basis on physiological characteristics of lipid metabolism in chicks

Homer1a Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Stress After Ischemic Reperfusion Injury by Inhibiting the PERK Pathway

Homer1a is the short form of a scaffold protein that plays a protective role in many forms of stress. However, the role of Homer1a in cerebral ischemia/reperfusion (I/R) injury and its potential mechanism is still unknown. In this study, we found that Homer1a was upregulated by oxygen and glucose deprivation (OGD) and that overexpression of Homer1a alleviated OGD-induced lactate dehydrogenase (LDH) release and cell death in cultured cortical neurons. After OGD treatment, the overexpression of Homer1a preserved mitochondrial function, as evidenced by less cytochrome c release, less reactive oxygen species (ROS) production, less ATP and mitochondrial membrane potential (MMP) loss, less caspase-9 activation, and inhibition of endoplasmic reticulum (ER) stress confirmed by the decreased expression of phosphate-PKR-like ER Kinase (p-PERK)/PERK and phosphate- inositol-requiring enzyme 1 (p-IRE1)/IRE1 and immunofluorescence (IF) staining. In addition, mitochondrial protection of Homer1a was blocked by the ER stress activator Tunicamycin (TM) with a re-escalated ROS level, increasing ATP and MMP loss. Furthermore, Homer1a overexpression-induced mitochondrial stress attenuation was significantly reversed by activating the PERK pathway with TM and p-IRE1 inhibitor 3,5-dibromosalicylaldehyde (DBSA), as evidenced by increased cytochrome c release, increased ATP loss and a higher ROS level. However, activating the IRE1 pathway with TM and p-PERK inhibitor GSK2656157 showed little change in cytochrome c release and exhibited a moderate upgrade of ATP loss and ROS production in neurons. In summary, these findings demonstrated that Homer1a protects against OGD-induced injury by preserving mitochondrial function through inhibiting the PERK pathway. Our finding may reveal a promising target of protecting neurons from cerebral I/R injury