Segmentation and Descriptors for Pattern

Image segmentation is an essential preliminary step in most automatic pictorial pattern recognition. The purpose of representation and description is used to be the application of Pattern. In the application of image processing, we have to choose an approach and to do description, just like recognition of the image. Keywords: image processing, Patter

Common Fixed Point Theorem in Intuitionistic Fuzzy 2- Metric Spaces for Integral Inequality

In this paper, we prove a common fixed point theorem for weakly compatible maps in intuitionistic Fuzzy 2- metric space for integral type inequality.   2010 Mathematics Subject Classification: 47H10, 54H25.   Key words and phrases: Intuitionistic fuzzy 2- metric space, weakly Compatible mappings, Common fixed point

Development of sportswear with enhanced moisture management properties using cotton and regenerated cellulosic fibres

The effect of fibre composition on moisture management properties and peak heat flux (qmax) values of one commercialsport garment and six knitted fabrics (sportswear), composed of 100% polyester, 100% cotton, 100% modal, and blend ofpolyester with cotton and modal, have been investigated. The moisture management properties are assessed by using themoisture management tester, and the feeling of coldness or warmth is assessed by measuring qmax value on KES-F7 Thermolabo II. Blending polyester fibre with cotton and modal has improved moisture management properties of the fabrics incomparison to 100% polyester fabric. qmax study also indicates that polyester/cotton and polyester/modal blend fabrics arecooler as compared to 100 % polyester fabric

Design and synthesis of novel s-triazine based coumarin, quinoline, morpholine and isoniazid derivatives and their antitubercular and antimicrobial evaluation

285-292This study presents the synthesis of novel s-triazine derivatives. The synthetic route to final s-triazines consists of two nucleophilic substitution reactions of 4-hydroxy benzonitrile and 8-hydroxyquinoline or 8-hydroxy-7-methyl coumarin or isoniazid or morpholine with 2,4,6-trichloro-1,3,5-triazine resulting in 2,4-disubstituted-6-chloro-1,3,5-triazine derivatives to introduce the various amines functionality. The structures of the compounds have been elucidated with the aid of IR, 1H and 13C NMR, mass spectroscopy and elemental analysis. The title compounds have then been investigated for their in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv strain by using BACTEC MGIT and Lowenstein-Jensen MIC method and antimicrobial evaluation

DESIGNING OF 2, 5-DISUBSTITUTED-1,3,4-THIADIAZOLE DERIVATIVES FOR THEIR ANTICONVULSANT POTENTIAL

QSAR is the study of quantitative relationships between biological activity and the physicochemical properties of a common parent structure molecule. CS chemoffice software utilized for QSAR of series. The reported IC50 values were converted to negative log IC50 values, which were correlated with various descriptors. Upon stepwise, multiple, and sequential regression analysis of descriptor, the statistically significant QSAR equations were obtained. The correlation between the physicochemical parameters and the biological activity were found using the least squares method. The equations having good correlation coefficient (r2), F-test value, SD values and minimum variance were validated by the cross validation method and IC50 and pIC50 values were calculated using Valstat. 5-Benzenesulphonamido-1,3,4-thiadiazol-2-sulphonamide, was designed as parent structure

Epidemiology and Clinicopathological Profile of Renal Cell Carcinoma: A Review from Tertiary Care Referral Centre

Renal cell carcinoma (RCC) accounts for 3% of all adult cancers and 85% of all kidney tumours. Incidence of RCC is lower in Asian region, particularly in India, probably due to lack of reporting. Most of the data about RCC are from Western countries; and data from India are scarce, especially regarding para-neoplastic syndromes. We sought to determine the epidemiology, clinicopathological profile and management of RCCin a tertiary care centre in Western India. This was a retrospective study that involved data analysis of records of RCC patients who presented to our institution from April 2016 to February 2020. Laboratory investigations, including tests for paraneoplastic syndrome (PNS), and relevant radiologic investigations were performed and treatment was offered according to the stage, patient factors and available modalities. A total 142 RCC patients were included in the study. The median age of presentation was 58 years. Most of the patients (67%) were symptomatic, and 33% of the patients were asymptomatic, and the RCC was diagnosed incidentally. A large number of patients (56.3%) had PNS. The most common histopathologic type of RCC was clear cell carcinoma (68.8%), followed by papillary (20%) and chromophobe (8%) carcinoma. 40% of carcinomas with sarcomatoid differentiation were seen in patients under 50 years of age. Two cases of multicystic RCC were both seen in patients less than 50 years of age. 65.5% of the patients presented at Stage 1 and 2. Most surgeries (71.2%) were done in a minimally invasive manner. A significant number of patients were asymptomatic, in which RCC was detected incidentally. The age of presentation was earlier, yet the patients had a higher tumour stage. More than half of the patients had PNSs. Despite growing trend towards Western data, the significantly higher number of patients with PNSs and early age of presentation suggest inherent differences in tumour biology, possibly related to differences in genetic and environmental factors

MOLECULAR DETECTION OF HUMAN RHINOVIRUS IN RESPIRATORY SAMPLES OF SWINE FLU NEGATIVE NORTH INDIAN CHILDREN WITH FLU-LIKE ILLNESS

Objectives: Flu-like illness may also be caused by different respiratory viruses other than influenza. Human rhinovirus (HRV) shows almost flu-likesymptoms. The purpose of this study is the molecular detection of HRV in throat swab of swine flu negative North Indian children during the years2012 and 2013. Reverse transcriptase (RT) - polymerase chain reaction (PCR) amplification of 5'non-coding region (NCR) was used for HRV detectionfollowed by cell culture isolation of HRV.Methods: PCR confirmed swine flu negative throat swab samples were collected from the Department of Microbiology, Sanjay Gandhi Post GraduateInstitute of Medical Sciences, Lucknow, Uttar Pradesh, India. The RNA isolation of samples was done using the QIAampViral RNA Mini Kit (Qiagen),followed by single step RT-PCR amplification (AgPath-ID, Life Technologies). All PCR positive HRV samples were cell cultured in HeLa and HEp-2 celllines for viral isolation.®Results: 135 swine flu negative throat swab samples were examined. Out of which 34 samples (25.2%) were found HRV positive by RT-PCR, while onlyfour samples (11.8%) were culture positive on HeLa cell line. Younger children (0-4 year) were found more susceptible to HRV infection. This studyindicated the highest prevalence of HRV (37.0%) during the months (September-October) of the Autumn season in 2012 and 57% in Winter-springseason (February-March) during 2013.Conclusion: HRV may be a cause of flu-like symptoms in swine flu suspected North Indian children with a higher rate during Autumn and Springseason. Molecular detection of HRV using RT-PCR is more sensitive than cell culture assay.Keywords: Human rhinovirus, Swine flu, Influenza-like illness, Lower respiratory tract infections

Prospective subjective evaluation of swallowing function and dietary pattern in head and neck cancers treated with concomitant chemo-radiation

Aim : Prospective subjective evaluation of swallowing function and dietary pattern in locally advanced head and neck cancer patients treated with concomitant chemo-radiotherapy (CRT). Materials and Methods : Prospective evaluation of swallowing function with performance status scale for head and neck cancer patients (PSSHN) at pre-CRT, CRT completion and at subsequent follow-ups in adult with loco-regionally advanced head and neck squamous cell carcinoma (HNSCC) patients. Results : In 47 patients (40 male, seven females; mean age 53; 72% smoker 53%, oropharyngeal cancer), the mean total PSSHN score at pre-CRT was 258.5 and decreased to 225.2 and 219.2 at two and six months respectively. Understandability of speech, normalcy in diet and eating in public at pre-CRT and six months were 91.5 and 84.4; 80.4 and 63.1; 87.3 and 76.6 respectively. In univariate analysis, pre-CRT PSSHN scores were significantly lesser in patients with severe pre-CRT dysphagia (P = 0.001), hypopharyngeal cancer (P = 0.244) and advanced T-stage (T3/4) disease (P = 0.144). At CRT completion, there was significant reduction of PSSHN scores in patients with severe pre-CRT dysphagia (P = 0.008), post-CRT weight loss (>10%) and disease progression (P = 0.039). At two months and six months, 17 (57%) and 11 (73.5%) patients respectively showed change in dietary habit. Mean increase in meal time was 13% and 21% at two and six-month follow-up. Conclusions : HNSCC patients show deterioration in swallowing function after CRT with normalcy of diet in maximum and eating in public least affected. Pre-CRT severity of dysphagia, weight loss> 10% and disease progression have significant correlation with higher swallowing function deterioration after CRT