Meckel’s diverticulum: a cadaveric case report

Meckel's diverticulum is the common congenital anamoly of the gastrointentestinal tract, caused due to failure of involution of vitelline duct after seventh or eighth week of intra-uterine life. It is usually present within the last 90cm of terminal ileum.  Histologically, Meckel's diverticulum consists of all layers of small intestine. Rarely, heterotopic tissue is present derived from gastric or pancreatic tissue. In the case presented here, Meckel's diverticulum was found on the ante mesenteric border of the ileum with no peritoneal attachment during routine Anatomy cadaveric dissection. It was present 26cm proximal to the ileocecal junction, with no attachment to umbilicus. It’s blood supply was derived from the vitelline artery. Histological examination revealed the presence of 3 layers: mucosa, submucosa and muscularis propria with no heterotopic tissue

A case study of musculocutaneous nerve variations

Background: Musculocutaneous nerve variations may become evident clinically or may be encountered during surgery. These are of importance for neurologists, traumatologists and orthopaedicians.Methods: 70 upper limbs from 35 embalmed cadavers were studied during the study period of 2 years during routine dissection in the Department of Anatomy S.M.S. Medical College, Jaipur, India.Results: A branch from musculocutaneous nerve arising at a distance of 6 cm from acromion process of scapula.A branch arising from median nerve at a distance of 14.4 cm from acromion process and joins with the branch of musculocutaneous nerve at around 17.4 cms away from the acromion process. The nerve thus formed by the union of the branches from median and musculocutaneous nerves further goes and joins the Radial nerve just before entering the cubital fossa.Conclusions: While performing shoulder surgery, the palpation of musculocutaneous nerve is of great importance, as it may get injured by the retractors which are placed under the coracoid process during the surgery. Frequent shoulder dislocation, coracoid process grafting and arthroscopy might damage the nerve as well as the muscle. This article might fulfil the gap in the original research work in this field.

Enhancement of lipase production by ethyl methane sulfonate mutagenesis of soil fungal isolate

Strain improvement through random mutagenesis is an extremely developed practice and it plays an important role in the economic growth of microbial agitation processes. The present study comprises of genetic improvement of fungus isolated from petrol pump soil by ethyl methane sulfonate (EMS) mutagenesis for increased production of extracellular lipase. Random mutagenesis was performed by incubating the spore suspension of fungus with EMS at a concentration of 5% (v/v) and 8% (v/v) for 30, 60 and 90 min, respectively. Control set was prepared by incubating the spore suspension with sterile distilled water. Control plate showed maximum number of fungal colonies whereas number of colonies was decreased as we increased exposure time of EMS from 30 to 90 min. The lipase activity of six mutagenic strains and wild strain was determined under submerged fermentation and solid state fermentation. Treated culture named as EMS5%-60min (obtained after 60 min exposure with 5% EMS) exhibited maximum activity (32.09 ± 1.84 IU/ml/min) in SmF as compared to wild strain (8.77 ± 3.52 IU/ml/min) and another treated strain named as EMS8%-90min (obtained after 90 min exposure with 8% EMS) exhibited maximum activity (7.99 ± 0.12 IU/g/min) in SSF as compared to wild strain (1.77 ± 0.71 IU/g/min). The activity of mutagenic strain i.e. EMS5%-60min was increased to 365.90% as compared to 100% activity of wild strain in SmF whereas activity of another mutagenic strain i.e. EMS8%-90min was increased to 451.41% as compared to 100% activity of wild strain in SSF

Domestic Violence against Women during the Covid-19: A Case Study of Bihar (India)

The Covid-19 pandemic revealed that the socioeconomic challenges in developing countries intersect within and beyond the dynamics of caste, class, space, and most importantly, gender. The recent outbreak of the Covid-19 pandemic compelled the entire human population to survive on the brink of uncertainty. The subsequent lockdown witnessed an upsurge in domestic abuse cases across the globe, making us realize how the four walls of the familial space turned into a hotbed of the \u27shadow pandemic\u27 resulting from the socioeconomic disparities and individual frustration during difficult times. India also witnessed a sudden surge in domestic violence cases, often called a shadow pandemic. While some got reported, many went without being documented in any forum. In this regard, this research is a case study of Bihar (India), which encountered a higher rate of domestic violence during the pandemic than other states such as Delhi, Haryana, Uttar Pradesh, and Himanchal Pradesh. This empirical study examines the economic, psychological, and social factors responsible for the surge in domestic abuse in Bihar during the Covid-19 pandemic

Role of ‘One Stop Crisis Centre’ in Identifying and Assisting Victims of Violence in an Indian Health Care Setup

Introduction: Cases of female targeted violence often go uncounted in India. To identify the unreported cases of violence, Sukoon was established in 2014 as a hospital-based ‘One Stop Crisis Centre’ (OSCC). Sukoon provides counselling, police assistance and legal aid to the victims. The aim of the present study was to recognize the role of Sukoon in preventing violence against women (VAW) in the region.Methods: Secondary data was extracted from 430 victims who approached Sukoon from August 2014 through January 2017. Data was collected on different variables: age, marital status, nature of violence, medium through which victims approached Sukoon and type of assistance provided. Significance of association of studied factors with the type of assault was investigated using ?2 test.Results: Age of study-victims ranged from 4 to 75 years with a median age of 26 years and mean age of 27.61 years with standard deviation of 10.56 years. Major types of VAW (96.51%) were domestic violence, sexual assault, physical assault and poisoning. The types of violences were significantly associated with victims’ age (?2 =5.76, d.f.=1, p<0.05) and marital status (?2 = 98.23, d.f=4, p<0.001). About 78% of victims were identified from Sukoon through screening and counseling. Around 69% of the cases were resolved directly by Sukoon or through police assistance.Conclusion: The above results indicate a significant role of Sukoon in screening victims of violence and providing them required assistance within the hospital environment in one location. Such centers should be further promoted by the government to address the issues of VAW

Gallbladder malignancy an old soul revisited-ultrasonography and contrast enhanced computed tomography evaluation in tertiary care center in South West Bihar

Background: Gallbladder (GB) malignancy is the commonest biliary tract carcinoma. It ranks fifth among the malignancies of the gastrointestinal tract and in all encompasses about 1-3% of all malignancies. Its peak occurrence is in the 5th decade or older with a female predilection. The most cases of GB malignancy are seen along the Ganga river delta region in India. The median survival rate in GB malignancy is approximately 6 months. Methods: A cross-sectional observational study was conducted in the Department of Radiology, Narayan Medical College and Hospital Sasaram over a period of 12 months from August 2022 to September 2023. A total of 40 patients were included on the basis of signs and symptoms of gallbladder carcinoma and underwent USG and CT scan for preoperative radiological diagnosis, following operation all the resected specimens were sent for histopathological evaluation. The diagnostic accuracies of USG and CT scan were then compared against histopathological diagnosis by using Kappa statistics. Results: In the present study, the mean age of the patients was 60 (range: 40-80 years) with female preponderance. About 40% of the gall-bladder were contracted and reduced in size and 35% large and distended on USG examination, while 45% of the gall-bladder were contracted and reduced in size and 37.5% distended and large on CT examination. Approximately 37.5% had irregularly thickened wall and 25% diffusely thickened wall on USG and 25% of gallbladder wall were diffusely thickened and 45% irregularly thickened on CT scan. The present study showed hepatic parenchymal invasion to be 25% on USG and 37.5% on CT scan. The sensitivity and specificity of USG in diagnosing GB carcinoma were 94.2% and 71.4% respectively. Similarly, the sensitivity and specificity of CT scan in detecting GB carcinoma were 97.1% and 83.3% respectively. The test of agreement (Kappa test) revealed an almost 90% agreement between the two procedures meaning that the two diagnostic modalities are almost comparable in diagnosing gall bladder carcinoma. Conclusions: As the histopathological diagnosis of the present study correlated well with USG and CT scan findings in the diagnosis of gallbladder carcinoma; it can be concluded that both USG and CT scan are useful imaging modalities for diagnosing this disease. However, CT scan is more sensitive and specific in predicting gall bladder carcinoma as compared to USG

Gender disparities in OHNS residency awards

Gender disparities are well established in the surgical field, despite increasing prevalence of women in surgical specialties. This study aims to evaluate gender disparities in otolaryngology residency training with a focus on awards in residency. 122 OHNS training programs were sent emails with a survey link requesting participation. Questions including number of women residents as well as questions pertaining to specific awards were detailed. Primary outcome measures were total number and percentages of award recipients that were women. Further analysis stratification was completed for geographic location and award type. 15% of programs contacted participated in our survey. Data was gathered from 2010-2019. The percentage of women in a given OHNS residency program ranged from 0% to 55%. Awards distributed to women in a program ranged from 6% to 50%. Women were disproportionately awarded in all residency program except one, in which they were over-awarded. Overall, women were found to be 42% less likely to receive a residency award compared to men (OR, 0.58; 95% CI, 0.42 to 0.81; P = 0.001). Statistical significance was identified in awards of academic excellence, where women residents were found to be 54% less likely to receive an award, as well as in teaching awards, where women were 51% less likely to receive an award. When addressing whether the responder believed gender bias existed in otolaryngology residency, 58% felt there may be some bias, while 24% responded yes, and 12% responded no. Gender inequalities exist at several stages within an individual’s academic career including at the resident trainee level. This study demonstrates that women are disproportionately distributed residency awards when compared to their male colleagues in OHNS. Knowledge of these disparities must be made to prevent a negative long-standing impact on women residents within OHNS programs