6 research outputs found

    Evaluation of contact spermicidal potential of Lantana camara leaf extracts on human spermatozooa

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    Background: The Present study was designed to evaluate the spermicidal potential of various Lantana camara leaf extracts on healthy human spermatozoa.Methods: Four different extracts viz. Petroleum ether, Chloroform, Methanol and Water were prepared and diluted to various concentrations. These were then treated with suitably diluted human semen samples. Various parameters like sperm motility, sperm viability, sperm count, hypoosmotic swelling, acrosomal status and function were noted.Results: The results showed that methanolic and aqueous extracts possessed maximum spermicidal potential in terms of above mentioned sperm health and function parameters. Therefore, methanolic and aqueous extracts were further studied for In-vitro evaluation of pro-oxidant activity by detection of ROS generation using fluorescent probe detection method.Conclusions: The results revealed that both methanolic and aqueous extracts of Lantana camara possessed pro-oxidant potential which could be attributed for its observed contact spermicidal activity

    Climate Resilient Energy Efficient Design in Architecture (CREEDA):a design manual for India

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    The goal of the CREEDA manual is to immerse Indian architects in the process of designing buildings that are resilient to a changing climate whilst also being highly energy efficient. The approach we take in the manual is one of “learning by doing”. That is, rather than teaching you concepts or calculations, we show how to reason out a strategy for the design of your building at a very early stage in the design process – maybe even before you have drawings. Thus, we wish architects to learn how to PLAY with these types of tools through a process of self-education. Hence the word “CREEDA” which is Sanskrit for “the act of playing”.The manual contains a series of case study buildings – each based on a real building in India. We show readers how to transform data for such buildings into a free-to-use tool called ZEBRA, use current and future weather data for any part of India at a 25 km spatial resolution and leverage existing knowledge and practices within India to achieve our goal of a truly low-energy climate resilient building. We take each case study building through carefully selected changes to expose the ramifications of designing them differently – in effect showing users how to PLAY with their own designs

    Evaluation of contact spermicidal potential of Lantana camara leaf extracts on human spermatozooa

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    Background: The Present study was designed to evaluate the spermicidal potential of various Lantana camara leaf extracts on healthy human spermatozoa.Methods: Four different extracts viz. Petroleum ether, Chloroform, Methanol and Water were prepared and diluted to various concentrations. These were then treated with suitably diluted human semen samples. Various parameters like sperm motility, sperm viability, sperm count, hypoosmotic swelling, acrosomal status and function were noted.Results: The results showed that methanolic and aqueous extracts possessed maximum spermicidal potential in terms of above mentioned sperm health and function parameters. Therefore, methanolic and aqueous extracts were further studied for In-vitro evaluation of pro-oxidant activity by detection of ROS generation using fluorescent probe detection method.Conclusions: The results revealed that both methanolic and aqueous extracts of Lantana camara possessed pro-oxidant potential which could be attributed for its observed contact spermicidal activity

    The Effect of Teach One Reach One (TORO) on Youth Acceptance of Couple Violence

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    This study evaluated the impact of the Teach One Reach One intervention, a community-based participatory research project designed to address the co-occurrence of adolescent risk behaviors on acceptance of teen dating violence. Data were derived from 331 rural African American youth between 10–14 years of age who participated in caregiver-youth dyads as either: 1) peer lay health advisor dyads, or Ambassadors, 2) caregiver-youth dyads recruited by Ambassadors, or Allies, or 3) comparison dyads. The following study focuses on participating youth only and our results indicated that: 1) Ambassadors and Allies reported less acceptance of couple violence than youth within the comparison group, and 2) less family cohesion, greater family conflict, and greater knowledge of healthy dating behaviors predicted greater acceptance of couple violence. Our findings highlight the efficaciousness of the TORO intervention, which directly engaged participants in prevention efforts through community-based participatory research methods and the use of lay heath advisors
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