5,647 research outputs found

    Personal Identity

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    Our aim in this entry is to articulate the state of the art in the moral psychology of personal identity. We begin by discussing the major philosophical theories of personal identity, including their shortcomings. We then turn to recent psychological work on personal identity and the self, investigations that often illuminate our person-related normative concerns. We conclude by discussing the implications of this psychological work for some contemporary philosophical theories and suggesting fruitful areas for future work on personal identity

    Intramolecular integration within Moloney murine leukemia virus DNA

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    By screening a library of unintegrated, circular Moloney murine leukemia virus (M-MuLV) DNA cloned in lambda phage, we found that approximately 20% of the M-MuLV DNA inserts contained internal sequence deletions or inversions. Restriction enzyme mapping demonstrated tht the deleted segments frequently abutted a long terminal repeat (LTR) sequence, whereas the inverted segments were usually flanked by LTR sequences, suggesting that many of the variants arose as a consequence of M-MuLV DNA molecules integrating within their own DNA. Nucleotide sequencing also suggested that most of the variant inserts were generated by autointegration. One of the recombinant M-MuLV DNA inserts contained a large inverted repeat of a unique M-MuLV sequence abutting an LTR. This molecule was shown by nucleotide sequencing to have arisen by an M-MuLV DNA Molecule integrating within a second M-MuLV DNA molecule before cloning. The autointegrated M-MuLV DNA had generally lost two base pairs from the LTR sequence at each junction with target site DNA, whereas a four-base-pair direct repeat of target site DNA flanked the integrated viral DNA. Nucleotide sequencing of preintegration target site DNA showed that this four-base-pair direct repeat was present only once before integration and was thus reiterated by the integration event. The results obtained from the autointegrated clones were supported by nucleotide sequencing of the host-virus junction of two cloned M-MuLV integrated proviruses obtained from infected rat cells. Detailed analysis of the different unique target site sequences revealed no obvious common features

    Comment on `Formation of a Dodecagonal Quasicrystalline Phase in a Simple Monatomic Liquid'

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    In a recent paper M. Dzugutov, Phys. Rev. Lett. 70 2924 (1993), describes a molecular dynamics cooling simulation where he obtained a large monatomic dodecagonal quasicrystal from a melt. The structure was stabilized by a special potential [Phys. Rev. A46 R2984 (1992)] designed to prevent the nucleation of simple dense crystal structures. In this comment we will give evidence that the ground state structure for Dzugutov's potential is an ordinary bcc crystal

    Functionalism and Thinking Animals

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    Lockean accounts of personal identity face a problem of too many thinkers arising from their denial that we are identical to our animals and the assumption that our animals can think. Sydney Shoemaker has responded to this problem by arguing that it is a consequence of functionalism that only things with psychological persistence conditions can have mental properties, and thus that animals cannot think. I discuss Shoemaker’s argument and demonstrate two ways in which it fails. Functionalism does not rid the Lockean of the problem of too many thinkers

    Real space investigation of structural changes at the metal-insulator transition in VO2

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    Synchrotron X-ray total scattering studies of structural changes in rutile VO2 at the metal-insulator transition temperature of 340 K reveal that monoclinic and tetragonal phases of VO2 coexist in equilibrium, as expected for a first-order phase transition. No evidence for any distinct intermediate phase is seen. Unbiased local structure studies of the changes in V--V distances through the phase transition, using reverse Monte Carlo methods, support the idea of phase coexistence and point to the high degree of correlation in the dimerized low-temperature structure. No evidence for short range V--V correlations that would be suggestive of local dimers is found in the metallic phase.Comment: 4 pages, 5 figure
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