1,265 research outputs found
Landscape Analysis of George W. Pirtle Scout Reservation
To assist in detecting change over time for the forested landscape of George W. Pirtle Scout Reservation, Panola County, Texas, digital ortho-photography imagery (acquired 1996 and 2004) were used to designate forest cover types and hazard rating for forest insects and diseases. Status of camp grounds was ascertained and recommendations made for management using the GIS database created for the camp
Disruption of spinal cord white matter and sciatic nerve geometry inhibits axonal growth in vitro in the absence of glial scarring
BACKGROUND: Axons within the mature mammalian central nervous system fail to regenerate following injury, usually resulting in long-lasting motor and sensory deficits. Studies involving transplantation of adult neurons into white matter implicate glial scar-associated factors in regeneration failure. However, these studies cannot distinguish between the effects of these factors and disruption of the spatial organization of cells and molecular factors (disrupted geometry). Since white matter can support or inhibit neurite growth depending on the geometry of the fiber tract, the present study sought to determine whether disrupted geometry is sufficient to inhibit neurite growth. RESULTS: Embryonic chick sympathetic neurons were cultured on unfixed longitudinal cryostat sections of mature rat spinal cord or sciatic nerve that had been crushed with forceps ex vivo then immediately frozen to prevent glial scarring. Neurite growth on uncrushed portions of spinal cord white matter or sciatic nerve was extensive and highly parallel with the longitudinal axis of the fiber tract but did not extend onto crushed portions. Moreover, neurite growth from neurons attached directly to crushed white matter or nerve tissue was shorter and less parallel compared with neurite growth on uncrushed tissue. In contrast, neurite growth appeared to be unaffected by crushed spinal cord gray matter. CONCLUSIONS: These observations suggest that glial scar-associated factors are not necessary to block axonal growth at sites of injury. Disruption of fiber tract geometry, perhaps involving myelin-associated neurite-growth inhibitors, may be sufficient to pose a barrier to regenerating axons in spinal cord white matter and peripheral nerves
A hedonic analysis of factors impacting the value of planters on the used machinery market
A hedonic model was employed to examine factors that influence the resale price of row crop planters on the used machinery market. Planter sale data from 2016 to 2018 were utilized to conduct the analysis. Results suggested that the primary factors impacting planter resale prices were make, age, condition, planter configuration, row number, and row spacing. As a function of age (depreciation), planter values were generally determined to decrease at a decreasing rate. Finally, it was determined that there was a significant interaction between the variables make and age, suggesting that different planter makes depreciate differently
PPARĪ³2 Regulates a Molecular Signature of Marrow Mesenchymal Stem Cells
Bone formation and hematopoiesis are anatomically juxtaposed and share common regulatory mechanisms. Bone marrow mesenchymal stromal/stem cells (MSC) contain a compartment that provides progeny with bone forming osteoblasts and fat laden adipocytes as well as fibroblasts, chondrocytes, and muscle cells. In addition, marrow MSC provide an environment for support of hematopoiesis, including the development of bone resorbing osteoclasts. The PPARĪ³2 nuclear receptor is an adipocyte-specific transcription factor that controls marrow MSC lineage allocation toward adipocytes and osteoblasts. Increased expression of PPARĪ³2 with aging correlates with changes in the MSC status in respect to both their intrinsic differentiation potential and production of signaling molecules that contribute to the formation of a specific marrow micro-environment. Here, we investigated the effect of PPARĪ³2 on MSC molecular signature in respect to the expression of gene markers associated exclusively with stem cell phenotype, as well as genes involved in the formation of a stem cell
supporting marrow environment. We found that PPARĪ³2 is a powerful modulator of stem cell-related gene expression. In general, PPARĪ³2 affects the expression of genes specific for the maintenance of stem cell phenotype, including LIF, LIF receptor, Kit ligand, SDF-1, Rex-1/Zfp42, and Oct-4. Moreover, the antidiabetic PPARĪ³ agonist TZD rosiglitazone specifically affects the expression of āstemnessā genes, including ABCG2, Egfr, and CD44. Our data indicate that aging and anti-diabetic TZD therapy may affect mesenchymal stem cell phenotype through modulation of PPARĪ³2 activity. These observations may have important therapeutic consequences and indicate a need for more detailed studies of PPARĪ³2 role in stem cell biology
End states, ladder compounds, and domain wall fermions
A magnetic field applied to a cross linked ladder compound can generate
isolated electronic states bound to the ends of the chain. After exploring the
interference phenomena responsible, I discuss a connection to the domain wall
approach to chiral fermions in lattice gauge theory. The robust nature of the
states under small variations of the bond strengths is tied to chiral symmetry
and the multiplicative renormalization of fermion masses.Comment: 10 pages, 4 figures; final version for Phys. Rev. Let
The Paradoxical Forces for the Classical Electromagnetic Lag Associated with the Aharonov-Bohm Phase Shift
The classical electromagnetic lag assocated with the Aharonov-Bohm phase
shift is obtained by using a Darwin-Lagrangian analysis similar to that given
by Coleman and Van Vleck to identify the puzzling forces of the Shockley-James
paradox. The classical forces cause changes in particle velocities and so
produce a relative lag leading to the same phase shift as predicted by Aharonov
and Bohm and observed in experiments. An experiment is proposed to test for
this lag aspect implied by the classical analysis but not present in the
currently-accepted quantum topological description of the phase shift.Comment: 8 pages, 3 figure
Methodological checklists for improving research quality and reporting consistency
This is the author accepted manuscript. The final version is available from Cambridge University Press via the DOI in this recor
Citation Networks in High Energy Physics
The citation network constituted by the SPIRES data base is investigated
empirically. The probability that a given paper in the SPIRES data base has
citations is well described by simple power laws, ,
with for less than 50 citations and for 50 or more citations. Two models are presented that both represent the
data well, one which generates power laws and one which generates a stretched
exponential. It is not possible to discriminate between these models on the
present empirical basis. A consideration of citation distribution by subfield
shows that the citation patterns of high energy physics form a remarkably
homogeneous network. Further, we utilize the knowledge of the citation
distributions to demonstrate the extreme improbability that the citation
records of selected individuals and institutions have been obtained by a random
draw on the resulting distribution.Comment: 9 pages, 6 figures, 2 table
Connectivity of Growing Random Networks
A solution for the time- and age-dependent connectivity distribution of a
growing random network is presented. The network is built by adding sites which
link to earlier sites with a probability A_k which depends on the number of
pre-existing links k to that site. For homogeneous connection kernels, A_k ~
k^gamma, different behaviors arise for gamma1, and gamma=1. For
gamma<1, the number of sites with k links, N_k, varies as stretched
exponential. For gamma>1, a single site connects to nearly all other sites. In
the borderline case A_k ~ k, the power law N_k ~k^{-nu} is found, where the
exponent nu can be tuned to any value in the range 2<nu<infinity.Comment: 4 pages, 2 figures, 2 column revtex format final version to appear in
PRL; contains additional result
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