52 research outputs found

    An energy stable C<sup>0</sup> finite element scheme for a quasi-incompressible phase-field model of moving contact line with variable density

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    In this paper, we focus on modeling and simulation of two-phase flow with moving contact lines and variable density. A thermodynamically consistent phase-field model with General Navier Boundary Condition is developed based on the concept of quasi-incompressibility and the energy variational method. Then a mass conserving and energy stable C0 finite element scheme is developed to solve the PDE system. Various numerical simulation results show that the proposed schemes are mass conservative, energy stable and the 2nd order for P1 element and 3rd order for P2 element convergence rate in the sense of L2 norm

    A Prediction Model for Identifying Seasonal Influenza Vaccination Uptake Among Children in Wuxi, China: Prospective Observational Study.

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    BACKGROUND: Predicting vaccination behaviors accurately could provide insights for health care professionals to develop targeted interventions. OBJECTIVE: The aim of this study was to develop predictive models for influenza vaccination behavior among children in China. METHODS: We obtained data from a prospective observational study in Wuxi, eastern China. The predicted outcome was individual-level vaccine uptake and covariates included sociodemographics of the child and parent, parental vaccine hesitancy, perceptions of convenience to the clinic, satisfaction with clinic services, and willingness to vaccinate. Bayesian networks, logistic regression, least absolute shrinkage and selection operator (LASSO) regression, support vector machine (SVM), naive Bayes (NB), random forest (RF), and decision tree classifiers were used to construct prediction models. Various performance metrics, including area under the receiver operating characteristic curve (AUC), were used to evaluate the predictive performance of the different models. Receiver operating characteristic curves and calibration plots were used to assess model performance. RESULTS: A total of 2383 participants were included in the study; 83.2% of these children (n=1982) were <5 years old and 6.6% (n=158) had previously received an influenza vaccine. More than half (1356/2383, 56.9%) the parents indicated a willingness to vaccinate their child against influenza. Among the 2383 children, 26.3% (n=627) received influenza vaccination during the 2020-2021 season. Within the training set, the RF model showed the best performance across all metrics. In the validation set, the logistic regression model and NB model had the highest AUC values; the SVM model had the highest precision; the NB model had the highest recall; and the logistic regression model had the highest accuracy, F1 score, and Cohen κ value. The LASSO and logistic regression models were well-calibrated. CONCLUSIONS: The developed prediction model can be used to quantify the uptake of seasonal influenza vaccination for children in China. The stepwise logistic regression model may be better suited for prediction purposes

    Integrated Pockels Laser

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    The development of integrated semiconductor lasers has miniaturized traditional bulky laser systems, enabling a wide range of photonic applications. A progression from pure III-V based lasers to III-V/external cavity structures has harnessed low-loss waveguides in different material systems, leading to significant improvements in laser coherence and stability. Despite these successes, however, key functions remain absent. In this work, we address a critical missing function by integrating the Pockels effect into a semiconductor laser. Using a hybrid integrated III-V/Lithium Niobate structure, we demonstrate several essential capabilities that have not existed in previous integrated lasers. These include a record-high frequency modulation speed of 2 exahertz/s (2.0×\times1018^{18} Hz/s) and fast switching at 50 MHz, both of which are made possible by integration of the electro-optic effect. Moreover, the device co-lases at infrared and visible frequencies via the second-harmonic frequency conversion process, the first such integrated multi-color laser. Combined with its narrow linewidth and wide tunability, this new type of integrated laser holds promise for many applications including LiDAR, microwave photonics, atomic physics, and AR/VR

    Quality of systemic cancer therapy in routine care: What are we measuring?

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    Channel Evolution under the Control of Base-Level Cycle Change and the Influence on the Sustainable Development of the Remaining Oil&mdash;A Case in Jiang Ling Depression, Jiang Han Basin, China

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    The extension of river channels is one of the key factors in determining the remaining oil distribution. Different sedimentary facies and bedding types of oil layers will form specific characteristics of remaining oil distribution after water injection development. Using massive drilling, core, logging, seismic, and production data, on the basis of sequence stratigraphy base-level cycle change, the river records and development history are restored, and the fine connectivity of reservoirs and the configuration relationship of production wells are studied. The following conclusions are drawn: (1) A sequence stratigraphic division scheme is established. In the established sequence framework, the types and characteristics of reservoir sand bodies are analyzed. The 2nd and 6th members of Yu yang formation can be divided into 2 long-term base level cycles, 5 medium-term base level cycles, and 17 short-term base level cycles. The evolution of the second and sixth members of the Yu yang formation shows a pattern of base level rising, falling and rising again; (2) the vertical sedimentary evolution sequence is underwater distributary channel distributary channel meandering channel distributary channel flood plain. The types of channel sand bodies developed from little overlap to more vertical or lateral overlap and then gradually changed to isolated type; (3) according to the structural location and development sequence, different types of reservoirs are identified. Combined with the statistics of the drilled data of Yu yang formation k2y4 in Fu I fault block, it is found that the connectivity rate of oil layer thickness (the ratio of oil layer connectivity thickness to total thickness of sand layer) within the oil-bearing area is 84.4%, and the connectivity rate of the number of layers (8) is 60%. The connectivity condition is relatively good

    Channel Evolution under the Control of Base-Level Cycle Change and the Influence on the Sustainable Development of the Remaining Oil—A Case in Jiang Ling Depression, Jiang Han Basin, China

    No full text
    The extension of river channels is one of the key factors in determining the remaining oil distribution. Different sedimentary facies and bedding types of oil layers will form specific characteristics of remaining oil distribution after water injection development. Using massive drilling, core, logging, seismic, and production data, on the basis of sequence stratigraphy base-level cycle change, the river records and development history are restored, and the fine connectivity of reservoirs and the configuration relationship of production wells are studied. The following conclusions are drawn: (1) A sequence stratigraphic division scheme is established. In the established sequence framework, the types and characteristics of reservoir sand bodies are analyzed. The 2nd and 6th members of Yu yang formation can be divided into 2 long-term base level cycles, 5 medium-term base level cycles, and 17 short-term base level cycles. The evolution of the second and sixth members of the Yu yang formation shows a pattern of base level rising, falling and rising again; (2) the vertical sedimentary evolution sequence is underwater distributary channel distributary channel meandering channel distributary channel flood plain. The types of channel sand bodies developed from little overlap to more vertical or lateral overlap and then gradually changed to isolated type; (3) according to the structural location and development sequence, different types of reservoirs are identified. Combined with the statistics of the drilled data of Yu yang formation k2y4 in Fu I fault block, it is found that the connectivity rate of oil layer thickness (the ratio of oil layer connectivity thickness to total thickness of sand layer) within the oil-bearing area is 84.4%, and the connectivity rate of the number of layers (8) is 60%. The connectivity condition is relatively good
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