Polymer Submicron- and Nano- Fibers: Applications in Healthcare, Drug delivery, Oil Spill Remediation and Print Transfer

[Abstract is not available

FORMULATION AND EVALUATION OF GASTRORETENTIVE TABLETS OF ANTIULCER DRUG

ABSTRACTGastroretentive floating drug delivery system is utilised to target drug release in the stomach or to the upper part of intestine. Lansoprazole is proton pump inhibitor intended for oral administration used as antiulcer agent. The present investigation involved formulation and evaluation of Gastroretentive floating tablets of Lansoprazole for prolongation of gastric residence time with a view to deliver the drug at sustained and controlled manner in gastrointestinal tract. The tablets of Lansoprazole were prepared by direct compression method using gas generating agent and different polymer combinations (HPMCK4M, HPMC K100M, Psyllium husk) . The prepared tablets of Lansoprazole were evaluated for hardness, thickness, friability, weight variation, drug content uniformity, buoyancy lag time, total floating time, swelling index, in-vitro dissolution study. The varying concentration of gas generating agent and polymers were found to affect on in-vitro drug release, floating lag time and swelling index. In vitro drug release of floating Gastroretentive tablet of Lansoprazole shown that the formulation F2 was found to be the best formulation as it releases 97.9% Lansoprazole in a controlled manner for extended period of time (upto 12 hrs.)Keywords: Lansoprazole, Gastroretentive, floating tablet, total floating time

Pharmaceutico Analytical Study of Kanakbindvarishta prepared by two different methods

Kanakbindvarishta is a self generated alcoholic preparation of Ayurveda. It is described in Charak Samhita in the context of Kushta Roga (skin disorders). Khadir (Acacia catechu) is a main ingredient in this formulation. It is used in condition like Kushta (mainly used in Kaphaja Kushta), Asthma, Cough, Fistula and Diabetes. In present study Kanakbindvarishta was prepared by two different methods, Pharmaceutical study was done along with analytical study. Analytical test of finished product like pH, specific gravity, refractive index, total solid content, viscosity, density, reducing sugar and alcohol content were done, LOD%, total Ash, pH and extractive value (water extractive, alcohol extractive) of raw material were also done. Two different type of Kanakbindvarishta compared with pharmaceutical as well as analytical aspect. As a result, slight changes were observed in both the preparations

Multiple Sector Identification Using Unique Referance Key

Using NoSQL storage like Mongodb, users can remotely store their data and enjoy the on-demand high quality applications and services from a shared pool of configurable computing resources, without the burden of local data storage and maintenance. The Unique ID system provides unique identification numbers to Indian residents. Unique key which would not just help the government to track down individuals, but would make life far easier for citizens as they would not have to submit multiple documents each time they want to avail a new public, private and government service. This system will contain personal details like name, address, marital status, photo, identification mark and fingerprint biometric. The unique key will be in the formed of 6 digit alphanumeric number to provide more security. This system helps to manage persons needs in his/her life span by using a unique reference key i.e. the number is used as valid key and it will fetch only the required details from the central database. This system will create government jobs for computer sector in the development, implementation and maintenance of the UID system. A single unique key is used therefore decreasing manual labour and increasing efficiency as every detail is available on the single click and reducing the efforts in maintaining different databases

Impact of Ayurvedic Interventions to improve the Nutritional Status among Adolescent Girls and Children under-five years in Devbhumi Dwarka district of Gujarat

Introduction: Anaemia is the global public health crisis, so also in India. The most direct connection between Pandu Roga and nutritional deficiency anaemia can be found in Ayurveda. Ayurvedic remedy was put through a clinical study on anaemic adolescent girls because anaemia is commonly prevalent that affects the society and the side effects of oral allopathic iron preparations are highly common. The present study assesses the impact of ayurvedic medicines in improving the nutritional status among anemic adolescent girls and severely underweight children under five years of age in Devbhumi Dwarka district of Gujarat. Method: The pre-post study was registered with Clinical Trial Registry of India conducted at Devbhumi Dwarka district of Gujarat. A total of 450 anaemic adolescent girls and 179 severely underweight children were screened respectively. Adolescent girls were provided with Faltrikadhi Kavath, Purnanavardi Mandur, and Amalaki Rasayan. Under-five children was given Shishubhaishaj granules in powder form. The study was conducted in three phases (Baseline, Intervention and Endline Assessment). Results: A total of 219 adolescent girls and 120 under-five children was evaluated during endline assessment. The mean improvement in Hb was +0.36 gm/dL for 219 subjects, however subjects (n=99) with better compliance shows significant improvement (+1.07 gm/dL, P=0.005). Under five children shows improvement in their anthropometric measurements (WAZ). Conclusion: The present study revealed that Ayurvedic intervention can improve Hb status of adolescent girls only with better compliance. The study also reports the reason of non-compliance and ways to address it

Biogenic silver nanoparticles: What we know and what do we need to know?

Nanobiotechnology is considered to be one of the fastest emerging fields. It is still a relatively new and exciting area of research with considerable potential for development. Among the inorganic nanomaterials, biogenically synthesized silver nanoparticles (bio-AgNPs) have been frequently used due to their unique physicochemical properties that result not only from their shape and size but also from surface coatings of natural origin. These properties determine antibacterial, antifungal, antiprotozoal, anticancer, anti-inflammatory, and many more activities of bio-AgNPs. This review provides the current state of knowledge on the methods and mechanisms of biogenic synthesis of silver nanoparticles as well as their potential applications in different fields such as medicine, food, agriculture, and industries.Web of Science1111art. no. 290

Polymer Submicron- and Nano- Fibers: Applications in Healthcare, Drug delivery, Oil Spill Remediation and Print Transfer

[Abstract is not available

Process of fabrication of submicron aligned hydrophobic and oleophilic fibre from polystyrene waste with controllable geometry using-citrus peel extract as solvent

The present invention discloses a simple mechanical method of fabrication of sub-micron aligned free standing hydrophobic and oleophilic fibers of polystyrene waste using extracts obtained from the peel of any citrus fruit such as orange, lemon, sweet lime, kinnow etc. as solvent. Fibers are aligned and useful in making different geometries. Process of making film using this process is facile and fast and film obtained is free standing film. Process set-up have minimum requirement and is inexpensive. This method is simple and flexible with respect to set-up and process. This process has the potential of being industrialized. Therefore, this method can be beneficial in dealing with both the orange peel and polystyrene waste

Novel and green processes for citrus peel extract: a natural solvent to source of carbon

Annual worldwide production of citrus fruits is estimated to be more than 120 MT, out of which nearly 50% is waste in terms of citrus peel. Although orange peel waste is further processed to yield valuable chemicals such as limonene and pectin, the processes involved are highly energy consuming and uneconomical and, therefore, have limited industrial acceptability. Here, we present cost-effective, low-energy, novel and green approaches to directly use the extract of citrus fruit’s peel as print transfer medium, solvent for recycling polystyrene waste and natural polymers. Furthermore, the fine solid suspended particles in the middle layer of the extract also find their use as a source of glassy carbon upon pyrolysis. This work may be an exemplary way of green engineering to use the waste as resource for environmental sustainability

Recycling of thermoplastic polystyrene waste using citrus peel extract for oil spill remediation

In this work, we report a low‐cost, less energy intensive, and an innovative way of recycling thermoplastic polystyrene (PS) waste objects into submicron, aligned fibers using extract from citrus peel, an agricultural waste. As‐fabricated recycled PS fabric is then structurally characterized and tested as an oil sorbent material. The hydrophobic‐oleophilic PS fabric is found to absorb 40.5 ± 3.6 g/g of oil, with 77.3% oil retention within 1 h. To investigate the practical application of recycled PS fabric for oil spills remediation, we tested its buoyancy properties in oil‐over‐water static and dynamic system besides examining their reusability. The as‐fabricated fabric floats on water after oil sorption indicating its high buoyancy and therefore can be collected easily after soaking the oil. This work is a simple illustration of systematic analysis of recycling two different waste materials (thermoplastic polystyrene and citrus peels) and reusing them into a more valuable produc