Ovarian tumor cases that were preoperatively diagnosed as benign but postoperatively confirmed as borderline or malignant after laparoscopic surgery

AbstractObjectiveLaparoscopic surgery is the gold standard for benign ovarian tumors because of its overall improved quality of life (QOL). However, some tumors diagnosed preoperatively as benign may be proven to be malignant by postoperative studies. The standard approach for the removal of a malignant ovarian tumor in our hospital is via laparotomy; however, there is no referential prognostic data on malignancies that are excised laparoscopically. To evaluate clinical and histological factors and prognosis, this study retrospectively reviewed patients who underwent surgery in our hospital, based on a preoperative diagnosis of benignancy, but later postoperative testing proved their tumors to be borderline or malignant.Participants and methodsThe study group comprised 1322 women who underwent a laparoscopic procedure in our hospital on the basis of a preoperative diagnosis of a benign ovarian tumor. The procedures were performed between 1995 and 2011. The rate of borderline and malignant cases, histology, and postoperative treatment were investigated.ResultsOf the 1322 patients, 15 (1.1%) patients were postoperatively diagnosed as having a borderline malignancy with various histological types and all of these patients had a good prognosis; four (0.3%) patients were postoperatively diagnosed as having a malignant tumor with various histological types; of these patients, two patients required emergency surgery. All four patients underwent additional surgery and chemotherapy with no recurrence to date.ConclusionSome tumors diagnosed preoperatively as benign proved postoperatively to be malignant. Appropriate postoperative treatment effectively improved the prognosis. Particular attention should be paid to a possible occult malignancy that may manifest postoperatively, especially in patients who underwent emergency surgery. We recommend preoperative magnetic resonance imaging, even for emergency cases, to improve preoperative diagnosis

Indication for Laparoscopically Assisted Vaginal Hysterectomy

When uterine weight is greater than 800 grams, total abdominal hysterectomy is more appropriate than laparoscopic-assisted vaginal hysterectomy

Electron microscopic studies of Acanthamoeba : 2 Morphological changes of cultured Acanthamoeba due to anti-amoebic agents

Morphological changes of Acanthamoeba in Peptone-Yeast-Glucose medium containing anti-amoebic agents were studied with transmission electron microscope. In fradiomycin-treated amoeba, decrease of acanthopodia, vacuolar formation in the ectoplasm and cell collapse were observed. In polyhexamethylene biguanide (PHMB)-treated amoeba, rupture of plasma membrane and degeneration of mitochondria were observed at the early stage. These results indicate that PHMB is more effective than fradiomycin for the treatment of Acanthaoeba keratitis

The Effect of Testosterone and Other Steroid Hormones on the Tumor Lymphocyte Lines Isolated from Chickens

ニワトリのマレック病およびリンパ腫症の腫瘍リンパ球増殖に及ぼすテストステロンほか各種ステロイドホルモンの効果ならびに3H－テストステロンに対するそれらの細胞の結合量を調べた. さらに,正常リンパ球におけるテストステロンの効果およびその結合量を調べた. テストステロンのほか,エストロジェンおよびグルココルチコイドにおいて,両腫瘍細胞あるいは一方の腫瘍細胞に対する増殖抑制効果が観察された. 正常リンパ球では,テストステロンは,Bリンパ球の生存率を減少させたが,Tリンパ球に対する効果はなかった. 3H－テストステロンに対する結合量は,腫瘍細胞では多量で,Bリンパ球でも比較的多かったが,Tリンパ球では少なかった. 以上の結果から,腫瘍細胞を含めたリンパ球におけるステロイドホルモンの効果は,多量のステロイドホルモンが細胞に結合することに基づくものと結論された. さらに,リンパ球の分化に関して,Tリンパ球は成熟のある時期にテストステロンに対する感受性を失なう一方,Bリンパ球は､その感受性を保持し続けることが示唆された

〈Cases Reports〉 Postoperative urinary stress incontinence after Le Fort colpocleisis

[Abstract] A 72-year-old woman, gravida 4 and para 2, came to our hospital with symptoms of pelvic prolapse. Pelvic examination was performed bya gynecologist and she was diagnosed with prolapse of the uterus. A pessary was inserted into the vagina for conservative treatment. As a result, the symptoms of uterine prolapse improved, but urinary urgency and stress incontinence appeared. The patient requested radical surgery, so we performed Le Fort colpocleisis. The surgery was completed successfully and she was discharged with well-healed wounds ten days later. Two weeks later urinary urgency and stress incontinence were developed. A second surgery, using TOT (transobturator tape) were performed by urologists. As a result, thesymptoms of urinary incontinence disappeared. We therefore report that combined treatment with colpocleisis and TOT is possible

WITHDRAWN: Ovarian tumor cases preoperatively diagnosed as benign but postoperatively confirmed as borderline or malignant after laparoscopic surgery

The Publisher regrets that this article is an accidental duplication of an article that has already been published http://dx.doi.org/10.1016/j.gmit.2013.07.002. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy