A Fuzzy Mining Algorithm for Association-Rule Knowledge Discovery

Due to increasing use of very large database and data warehouses, discovering useful knowledge from transactions is becoming an important research area. On the other hand, using fuzzy classification in data mining has been developed in recent years. Hong and Lee proposed a general learning method that automatically derives fuzzy if-then rules and membership functions from a set of given training examples using a decision table. But it is complex if there are many attributes or if the predefined unit is small. Hong and Chen improve it by first selecting relevant attributes and building appropriate initial membership functions. Based on Hong’s heuristic algorithm of membership functions and Apriori approach, we propose a fuzzy mining algorithm to explore association rules from given quantitative transactions. Experimental results on Iris data show that the proposed algorithm effectively induces more association rules

Experimental Observation of a Topological Phase in the Maximally Entangled State of a Pair of Qubits

Quantum mechanical phase factors can be related to dynamical effects or to the geometrical properties of a trajectory in a given space - either parameter space or Hilbert space. Here, we experimentally investigate a quantum mechanical phase factor that reflects the topology of the SO(3) group: since rotations by $\pi$ around antiparallel axes are identical, this space is doubly connected. Using pairs of nuclear spins in a maximally entangled state, we subject one of the spins to a cyclic evolution. If the corresponding trajectory in SO(3) can be smoothly deformed to a point, the quantum state at the end of the trajectory is identical to the initial state. For all other trajectories the quantum state changes sign

Numerical Investigation for the Bearing Performance of the Segmental Joint with Elastic Gasket

Detailed three-dimensional numerical models considering concrete indentation, bolts, elastic gasket (EG) and sealing gasket (SG) are established for the segmental joint with gaskets, and the load tests of the joints with EG and without EG are simulated and compared. The results reveal that the bearing performance of the joint with EG is very complex. In sagging moment scenarios, it can be divided into four stages by three key points “EG starts to open”, “joint external edge starts to contact” and “EG fully opened”. In hogging moment scenarios, it can be divided into three stages by two key points “SG opened” and “EG starts to open”. The EG has a significant effect on the joint bearing performance. It can soften the joint, which leads to the result that the average bending stiffness and ultimate bearing capacity of the joint with EG are evidently smaller and weaker than those of the joint without EG. With decreasing the joint axial force, this softening effect tends to be more obvious. Besides, for the two joints, the ultimate states of the joints subject to the bending moments are both that the concrete at the joint edges yields firstly, and it is necessary to protect or strengthen the corresponding concrete

Tuber indicum and T. lijiangense colonization differentially regulates plant physiological responses and mycorrhizosphere bacterial community of Castanopsis rockii seedlings

Black truffles and white truffles are widely studied around the world, but their effects on plant growth and physiological responses, and on the mycorrhizosphere bacterial community of the host plant remain unclear. Here, mycorrhizal colonization of Castanopsis rockii by Tuber indicum (Chinese black truffle) and T. lijiangense (Chinese white truffle), respectively, was induced in a greenhouse study, and their effects on host growth, physiological responses and mycorrhizosphere bacterial communities were compared. The results show that colonization of both Tuber species significantly increased leaf photosynthetic rate, leaf P concentration and mycorrhizosphere acid phosphatase activity, as well as richness of mycorrhizosphere bacterial communities of C. rockii seedlings. However, T. indicum colonization on the one hand significantly decreased tartrate content, bacterial acid phosphatase, phoC gene abundance in the mycorrhizosphere, and peroxidase (POD) activity of ectomycorrhizal root tips, but on the other hand increased mycorrhizosphere pH and superoxide dismutase (SOD) of ectomycorrhizal root tips, compared to T. lijiangense colonization. Moreover, principal coordinate and β-diversity analyses show significant differences in mycorrhizosphere bacterial community composition between T. indicum and T. lijiangese colonized C. rockii seedlings. Finally, the relative abundance of the bacterium Agromyces cerinus significantly correlated to mycorrhizosphere acid phosphatase activity and leaf P concentration, suggesting that this bacterium might play an important role in P mobilization and acquisition. Overall, these results suggest that T. indicum and T. lijiangense differently regulate their host plant’s physiological responses and mycorrhizosphere bacterial community

Integrating virtual reality and Building Information Modeling for improving highway tunnel emergency response training

During the last two decades, managers have been applying Building Information Modeling (BIM) to improve the quality of management as well as operation. The effectiveness of applications within a BIM environment is restrained by the limited immersive experience in virtual environments. Defined as the immersive visualization of virtual scenes, Virtual Reality (VR) is an emerging technology that can be actively explored to expand BIM to more usage. This paper highlights the need for a structured methodology for the integration of BIM/VR and gives a generic review of BIM and VR in training platforms for management in infrastructures. The rationales for fire evacuation training were formed based on the review. Then, methods of configuring BIM + VR prototypes were formulated for emergency response in highway tunnels. Furthermore, a conceptual framework integrating BIM with VR was proposed to enable the visualization of the physical context in real-time during the training. The result indicated that, extended to the training system of highway management via the “hand” of BIM, the VR solution can benefit more areas, such as the cost of fire evacuation drills in highway tunnels and the tendency of accidents to occur in the emergency response

Evaluation of Anti-tumor and Chemoresistance-lowering Effects of Pectolinarigenin from Cirsium japonicum Fisch ex DC in Breast Cancer

Purpose: To investigate the antitumor and chemoresistance-lowering effects of pectolinarigenin on breast cancer cells.Methods: Pectolinarigenin was purified by a combination of silica gel and Sephadex LH-20 column chromatography from ethanol extracts of the aerial parts of C. japonicum DC. Breast cancer selfrenewal properties were tested by colony formation and tumor sphere formation assays. Thereafter, real-time polymerase chain reaction (PCR) was used to detect breast cancer stem cell markers. Furthermore, the effect of pectolinarigenin on breast cancer cell was evaluated by chemoresistance using 3-(4,5-dimethyl-2 thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) assay. Finally, tumor formation in nude mice was used to test the effect of pectolinarigenin on tumorigenicity of breast cancer cells in vivo.Results: The results showed that pectolinarigenin, extracted from Cirsium japonicum Fisch. ex DC., inhibited tumor cell self-renewal in MCF-7 breast cancer cells. Pectolinarigenin (25 μM) caused significant inhibition of colony formation (61.23 %, p < 0.001) and tumor sphere formation (59.49 %, p < 0.01) in MCF-7. The inhibitory effects were associated with changes in breast cancer stem cell markers. Treatment of breast cancer cells with pectolinarigenin reduced the chemoresistance of the cells to doxorubicin. At the same time, mRNA expression of chemoresistance genes (ATP binding cassette subfamily G member 2, ABCG2 and ATP binding cassette subfamily B member 1, MDR1) was repressed by pectolinarigenin. The inhibition efficiency of MDR1 and ABCG2 by 10 μM pectolinarigenin treatment was about 59.29 (p < 0.01) and 46.48 % (p < 0.01), respectively. Furthermore, pectolinarigenin reduced tumor mass in nude mice xenograft model.Conclusion: Pectolinarigenin inhibits breast cancer stem cell-like properties and lowers the chemoresistance of the cancer cells to chemotherapy. The results provide an insight into the mechanism of the anti-breast tumor effects and an experimental basis for the use of pectolinarigenin to enhance treatment of patients with breast cancer.Keywords: Pectolinarigenin, Cancer stem cells, Breast cancer, Chemoresistance, Cirsium japonicum Fisch. ex D