75 research outputs found

    QTL analysis for yield-related traits under different water regimes in maize

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    Drought is one of the most essential factors influencing maize yield. Improving maize varieties with drought tolerance by using marker-assisted or genomic selection requires more understanding of the genetic basis of yield-related traits under different water regimes. In the present study, 213 F2:3 families of the cross of H082183 (drought-tolerant) × Lv28 (drought susceptible) were phenotyped with five yield-related traits under four well-watered and six drought environments for two years. Quantitative trait loci analysis identified 133 significant QTLs (94 QTLs for ear traits and 39 QTLs for kernel traits) based on single environment analysis. The joint-environment analysis detected 25 QTLs under well-watered environments (eight QTLs for ear length, eight for ear diameter, one for ear weight, two for kernel weight per ear, and six for 100-kernel weight), and nine QTLs under water-stressed environments (two QTLs for ear length, three for ear diameter, one for ear weight, one for kernel weight, and two for 100-kernel weight). Among these joint-environment QTLs, one common QTL (qEL5) was stably identified at both of the water regimes. Meanwhile, two main-effect QTLs were detected in the well-watered environments, i.e. qEL10 for ear length and qHKW2 for 100-kernel weight. Also, qED8, qEW8, and qKW8 were found to be located in the same interval of Chr. 8. Similarly, qEL4s and qKW4s were found to be located in the same interval under water-stressed environments. These genomic regions could be candidate targets for further fine mapping and marker-assisted breeding in maize

    Electronic correlations and flattened band in magnetic Weyl semimetal candidate Co3Sn2S2

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    The interplay between electronic correlations and topological protection may offer a rich avenue for discovering emergent quantum phenomena in condensed matter. However, electronic correlations have so far been little investigated in Weyl semimetals (WSMs) by experiments. Here, we report a combined optical spectroscopy and theoretical calculation study on the strength of electronic correlations in a kagome magnet Co3Sn2S2 and the influence of electronic correlations on its WSM state expected within a single-particle picture. The electronic kinetic energy estimated from our optical data is about half of that obtained from single-particle ab initio calculations, which indicates intermediate-strength electronic correlations in this system. Furthermore, comparing the energy ratios between the interband-transition peaks at high energies in the experimental and single-particle-ab-initio-calculation derived optical conductivity spectra with the electronic bandwidth renormalization factors obtained by many-body calculations enables us to estimate the Coulomb-interaction strength (U ~ 4 eV) of electronic correlations in Co3Sn2S2. Our many-body calculations with U ~ 4 eV show that a WSM state, which is characterized by bulk Weyl cones and surface Fermi arcs, survives in this correlated electron system. Besides, a sharp experimental optical conductivity peak at low energy, which is absent in the single-particle-ab-initio-calculation-derived optical conductivity spectrum but is consistent with the optical conductivity peaks obtained by many-body calculations, indicates that an electronic band connecting the two Weyl cones is flattened by electronic correlations and emerges near the Fermi energy in Co3Sn2S2. Our work paves the way for exploring flat-band-generated quantum phenomena in WSMs

    Anti-HIV-1 Activity of a New Scorpion Venom Peptide Derivative Kn2-7

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    For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently needed. We previously identified the antiviral activities of the scorpion-venom-peptide-derived mucroporin-M1 for three RNA viruses (measles viruses, SARS-CoV, and H5N1). In this investigation, a panel of scorpion venom peptides and their derivatives were designed and chosen for assessment of their anti-HIV activities. A new scorpion venom peptide derivative Kn2-7 was identified as the most potent anti-HIV-1 peptide by screening assays with an EC50 value of 2.76 µg/ml (1.65 µM) and showed low cytotoxicity to host cells with a selective index (SI) of 13.93. Kn2-7 could inhibit all members of a standard reference panel of HIV-1 subtype B pseudotyped virus (PV) with CCR5-tropic and CXCR4-tropic NL4-3 PV strain. Furthermore, it also inhibited a CXCR4-tropic replication-competent strain of HIV-1 subtype B virus. Binding assay of Kn2-7 to HIV-1 PV by Octet Red system suggested the anti-HIV-1 activity was correlated with a direct interaction between Kn2-7 and HIV-1 envelope. These results demonstrated that peptide Kn2-7 could inhibit HIV-1 by direct interaction with viral particle and may become a promising candidate compound for further development of microbicide against HIV-1

    Optimization for energy efficiency of underground building envelope thermal performance in different climate zones of China

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    The object of this article is to investigate the influence of thermal performance of envelopes in shallow-buried buildings on energy consumption for different climate zones of China. For the purpose of this study, an effective building energy simulation tool (DeST) developed by Tsinghua University was chosen to model the heat transfer in underground buildings. Based on the simulative results, energy consumption for heating and cooling for the whole year was obtained. The results showed that the relationship between energy consumption and U-value of envelopes for underground buildings is different compared with above-ground buildings: improving thermal performance of exterior walls cannot reduce energy consumption, on the contrary, may result in more energy cost. Besides, it is can be derived that optimized U-values of underground building envelopes vary with climate zones of China in this study. For severe cold climate zone, the optimized U-value of underground building envelopes is 0.8W/(m2·K); for cold climate zone, the optimized U-value is 1.5W/(m2·K); for warm climate zone, the U-value is 2.0W/(m2·K)

    Optimization for energy efficiency of underground building envelope thermal performance in different climate zones of China

    No full text
    The object of this article is to investigate the influence of thermal performance of envelopes in shallow-buried buildings on energy consumption for different climate zones of China. For the purpose of this study, an effective building energy simulation tool (DeST) developed by Tsinghua University was chosen to model the heat transfer in underground buildings. Based on the simulative results, energy consumption for heating and cooling for the whole year was obtained. The results showed that the relationship between energy consumption and U-value of envelopes for underground buildings is different compared with above-ground buildings: improving thermal performance of exterior walls cannot reduce energy consumption, on the contrary, may result in more energy cost. Besides, it is can be derived that optimized U-values of underground building envelopes vary with climate zones of China in this study. For severe cold climate zone, the optimized U-value of underground building envelopes is 0.8W/(m2·K); for cold climate zone, the optimized U-value is 1.5W/(m2·K); for warm climate zone, the U-value is 2.0W/(m2·K)

    Evaluating the Acute Effect of Stereoscopic Recovery by Dichoptic Stimulation Using Electroencephalogram

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    Amblyopia is a common developmental disorder in adolescents and children. Stereoscopic loss is a symptom of amblyopia that can seriously affect the quality of patient’s life. Recent studies have shown that the push-pull perceptual learning protocol had a positive effect on stereoscopic recovery. In this study, we developed a stereoscopic training method using a polarized visualization system according to the push-pull protocol. Dichoptic stimulation for 36 anisometropic and amblyopic subjects and 33 children with normal visual acuity (VA) has been conducted. Electroencephalogram (EEG) was used to evaluate the neurophysiological changes before, during, and after stimulation. For the anisometropic and amblyopic subjects, the statistical analysis demonstrated significant differences (p<0.01) in the beta rhythm at the middle temporal and occipital lobes, while the EEG from the normal VA subjects indicated no significant changes when comparing the results before and after training. We concluded that the dichoptic training in our study can activate the middle temporal visual area and visual cortex. The EEG changes can be used to evaluate the training effects. This study also found that the beta band EEG acquired during visual stimulation at the dorsal visual stream can be potentially used for predicting acute training effect. The results facilitated the optimization of the individual training plan
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