EVALUATION OF THE EFFECTIVENESS OF ANTI-ADHESIVE COATING ON A MODEL OF A LUNG WOUND IN AN EXPERIMENT

The problem of the adhesive process in surgery is still extremely relevant. The vast majority of studies of domestic and foreign authors are devoted to the formation of adhesions in the abdominal cavity. Interperitoneal fusion is still the cause of many diseases of the abdominal cavity [1,2,3]. First of all, these are directly peritoneal adhesions that occur both as a result of the inflammatory process and after surgery [4,5]. The question of the expediency of preventing adhesions in the abdominal cavity is now proven, and there is no doubt. At the same time, pleural adhesions in the modern classification of diseases, as an independent nosological unit, are absent. In this connection, a logical question arises: are the adhesions of the pleural cavity apathological process, or is the adhesiogenesis in this area a compensatoryadaptive reaction [6,7,8]? However, it is necessary to be sure that the induced increase in adhesiogenesis will not lead to the development of total intrapleural adhesions, weakening of the function of external respiration and the occurrence of respiratory failure. This fact requires close study and determines therelevance of the work

Evaluation of the Effectiveness of Anti-adhesive Coating on a Model of a Lung Wound in an Experiment

The problem of the adhesive process in surgery is still extremely relevant. The vast majority of studies of domestic and foreign authors are devoted to the formation of adhesions in the abdominal cavity. Interperitoneal fusion is still the cause of many diseases of the abdominal cavity [1,2,3]. First of all, these are directly peritoneal adhesions that occur both as a result of the inflammatory process and after surgery [4,5]. The question of the expediency of preventing adhesions in the abdominal cavity is now proven, and there is no doubt. At the same time, pleural adhesions in the modern classification of diseases, as an independent nosological unit, are absent. In this connection, a logical question arises: are the adhesions of the pleural cavity apathological process, or is the adhesiogenesis in this area a compensatoryadaptive reaction [6,7,8]? However, it is necessary to be sure that the induced increase in adhesiogenesis will not lead to the development of total intrapleural adhesions, weakening of the function of external respiration and the occurrence of respiratory failure. This fact requires close study and determines therelevance of the work