11 research outputs found
Hollow core fiber based interferometer for high temperature (1000 °C) measurement
A simple, cost effective high temperature sensor (up to 1000 °C) based on a hollow core fiber (HCF) structure is reported. It is configured by fusion splicing a short section of HCF with a length of few millimeters between two standard single mode fibers (SMF-28). Due to multiple beam interference introduced by the cladding of the HCF, periodic transmission dips with high spectral extinction ratio and high quality (Q) factor are excited. However, theoretical analysis shows that minor variations of the HCF cladding diameter may result in a significant decrease in the Q factor. Experimental results demonstrate that the position of periodic transmission dips are independent of the HCF length, but spectral Q factors and transmission power varies with different HCF lengths. A maximum Q factor of 3.3×104 has been demonstrated with large free spectral range of 23 nm and extinction ratio of 26 dB. Furthermore, the structure is proved to be an excellent high temperature sensor with advantages of high sensitivity (up to 33.4 pm/°C), wide working temperature range (from room temperature to 1000°C), high resolution, good stability, repeatability, relatively low strain sensitivity (0.46 pm/με), low cost and a simple and flexible fabrication process that offers a great potential for practical applications. A thorough theoretic analysis of the HCF based fiber structure has been proposed. The experimental results are demonstrated to be well matched with our simulation results
Singlemode-Multimode-Singlemode Optical Fiber Sensor for Accurate Blood Pressure Monitoring
A dual-channel single-mode-multi-mode-single-mode (SMS) fiber optic sensor encapsulated by polydimethylsiloxane (PDMS) was proposed for the first time, for the simultaneous monitoring of the brachial and radial arteries for accurate blood pressure prediction. With the help of the machine learning algorithm Support Vector Regression (SVR), the SMS fiber sensor can continuously and accurately monitor the systolic and diastolic blood pressure. Commercial sphygmomanometers are used to calibrate the accuracy of blood pressure measurement. Compared with the single-channel system, this system can extract more pulse wave features for blood pressure prediction, such as radial artery transit time (RPTT), brachial artery transit time (BPTT), and the transit time difference between the radial artery and the brachial artery (DBRPTT). The results show that the performance of dual-channel blood pressure monitoring is more accurate than that of single-channel blood pressure monitoring in terms of the absolute value of the correlation coefficient (R) and the average value of the difference between SBP and DBP. In addition, both the single-channel and dual-channel blood pressure monitoring are in line with the Association for the Advancement of Medical Devices (AAMI), but the average deviation (DM, 0.06 mmHg) and standard deviation (SD, 1.54 mmHg) of dual-channel blood pressure monitoring are more accurate. The blood pressure monitoring system has the characteristics of low cost, high sensitivity, non-invasive and capability for remote real time monitoring, which can provide effective solution for intelligent health monitoring in the era of artificial intelligence in the future
Plasma-Catalytic CO<sub>2</sub> Hydrogenation over a Pd/ZnO Catalyst: <i>In Situ</i> Probing of Gas-Phase and Surface Reactions
Plasma-catalytic CO2 hydrogenation is a complex chemical process combining plasma-assisted gas-phase and surface reactions. Herein, we investigated CO2 hydrogenation over Pd/ZnO and ZnO in a tubular dielectric barrier discharge (DBD) reactor at ambient pressure. Compared to the CO2 hydrogenation using Plasma Only or Plasma + ZnO, placing Pd/ZnO in the DBD almost doubled the conversion of CO2 (36.7%) and CO yield (35.5%). The reaction pathways in the plasma-enhanced catalytic hydrogenation of CO2 were investigated by in situ Fourier transform infrared (FTIR) spectroscopy using a novel integrated in situ DBD/FTIR gas cell reactor, combined with online mass spectrometry (MS) analysis, kinetic analysis, and emission spectroscopic measurements. In plasma CO2 hydrogenation over Pd/ZnO, the hydrogenation of adsorbed surface CO2 on Pd/ZnO is the dominant reaction route for the enhanced CO2 conversion, which can be ascribed to the generation of a ZnO x overlay as a result of the strong metal-support interactions (SMSI) at the Pd-ZnO interface and the presence of abundant H species at the surface of Pd/ZnO; however, this important surface reaction can be limited in the Plasma + ZnO system due to a lack of active H species present on the ZnO surface and the absence of the SMSI. Instead, CO2 splitting to CO, both in the plasma gas phase and on the surface of ZnO, is believed to make an important contribution to the conversion of CO2 in the Plasma + ZnO system
Fabrication of glycerol functionalized silica nanoparticles via pickering emulsion for durable, superhydrophobic fabrics
Stable oil-in-water Pickering emulsions were successfully developed via the simplest approach: amine-terminated polydimethylsiloxane with very high viscosity and low surface free energy was encapsulated by glycerol functionalized silica NPs using a rotor-stator device. The factors affecting the Pickering emulsions performance were investigated. At a certain process (silica NPs concentration: 3 wt%, Oil/water ratio: 1:20, emulsifying speed: 15,000 rpm, emulsifying time: 5 min), it gave smaller and more stable emulsions. Then the Pickering emulsion was applied on plain weave cotton and polyester fabrics through conventional pad-dry-cure method. The coated substrates showed superhydrophobicity and maintained good water-repellency even after 30 standard laundering cycles, which are attributed to the synergistic effect of low surface free energy composite and hierarchical roughness. By contrast, fabrics coated with classical emulsifiers stabilizing Pickering emulsion adopting the same recipes were quickly wetted by liquid droplets
Research on Dynamic Sealing Performance of Combined Sealing Structure under Extreme Working Conditions
This study investigates the sealing performance of a combined sealing structure under extremely high and low temperature conditions, considering potential issues like high-temperature aging and low-temperature brittle fracture, which can lead to sealing failure. EPDM rubber underwent uniaxial compression tests at high, low, and normal temperatures, then the sealing performance under extreme working conditions was compared with that under normal temperature conditions. Additionally, the influences of gasket parameters and gas pressure on the sealing performance were analyzed. The result shows that compared with the normal temperature conditions, the maximum von Mises stress is reduced by 65% and the effective sealing length and the maximum contact pressure is reduced by 40% under the high temperature conditions, while the maximum von Mises stress is increased by 7 times and the maximum contact pressure is increased by a remarkable 7 times under the low temperature conditions. In the range of 10–100 MPa, the increase in gas pressure aggravates the O-ring stress concentration and improves the sealing performance relatively. When the thickness of gasket is 0.85–1.05 mm, the stress concentration of the O-ring is lighter and the sealing performance is better
Predictors of HBeAg seroconversion after long-term nucleos(t)ide analogues treatment for chronic hepatitis B: a multicenter study in real clinical setting
Aims: To evaluate the HBeAg seroconversion rate in real clinical setting and explore its predictors in long-term nucleos(t)ide analogues (NAs) treatment for chronic hepatitis B (CHB). Methods: 251 patients were recruited from January 2001 to September 2009 in four hospitals in Hebei province, China, for this retrospective study. Clinical and laboratory data before and after treatment with lamivudine (LAM, 100 mg daily), adefovir (ADV, 10 mg daily), telbivudine (LDT, 600 mg daily), entecavir (ETV, 0.5 mg daily), and LAM/ADV combination were compared among three groups according to treatment outcomes: synchronous HBeAg loss and HBeAg seroconversion, anti-HBe development after treatment, and no anti-HBe. Adherence was also evaluated. Results: In real clinical setting, cumulative HBeAg seroconversion rates were 14.3%, 32.7%, 43.0%, 46.9%, and 50.5% after 1, 2, 3, 5, and 8 years, respectively. 45 patients (17.9%) were non-adherent. Adherence (p < 0.001, Hazard Ratio (HR) = 2.203), elevated alanine aminotransferase (ALT) levels (p < 0.001, HR = 2.049), and non-vertical transmission (p = 0.006, HR = 1.656) were predictors of HBeAg seroconversion. Conclusion: Adherence, elevated ALT, and non-vertical transmission are predictors of HBeAg seroconversion in CHB patients treated with NAs. Keywords: Chronic hepatitis B, Hepatitis B and antigens, Nucleos(t)ide analogue, Adherenc
Predictors of HBeAg seroconversion after long-term nucleos(t)ide analogues treatment for chronic hepatitis B: a multicenter study in real clinical setting
Aims: To evaluate the HBeAg seroconversion rate in real clinical setting and explore its predictors in long-term nucleos(t)ide analogues (NAs) treatment for chronic hepatitis B (CHB).
Methods: 251 patients were recruited from January 2001 to September 2009 in four hospitals in Hebei province, China, for this retrospective study. Clinical and laboratory data before and after treatment with lamivudine (LAM, 100Â mg daily), adefovir (ADV, 10Â mg daily), telbivudine (LDT, 600Â mg daily), entecavir (ETV, 0.5Â mg daily), and LAM/ADV combination were compared among three groups according to treatment outcomes: synchronous HBeAg loss and HBeAg seroconversion, anti-HBe development after treatment, and no anti-HBe. Adherence was also evaluated.
Results: In real clinical setting, cumulative HBeAg seroconversion rates were 14.3%, 32.7%, 43.0%, 46.9%, and 50.5% after 1, 2, 3, 5, and 8 years, respectively. 45 patients (17.9%) were non-adherent. Adherence (p < 0.001, Hazard Ratio (HR) = 2.203), elevated alanine aminotransferase (ALT) levels (p < 0.001, HR = 2.049), and non-vertical transmission (p = 0.006, HR = 1.656) were predictors of HBeAg seroconversion.
Conclusion: Adherence, elevated ALT, and non-vertical transmission are predictors of HBeAg seroconversion in CHB patients treated with NAs