1,206 research outputs found
Correlated Quantum Memory: Manipulating Atomic Entanglement via Electromagnetically Induced Transparency
We propose a feasible scheme of quantum state storage and manipulation via
electromagnetically induced transparency (EIT) in flexibly
multi-ensembles of three-level atoms. For different atomic array
configurations, one can properly steer the signal and the control lights to
generate different forms of atomic entanglement within the framework of linear
optics. These results shed new light on designing the versatile quantum memory
devices by using, e.g., an atomic grid.Comment: 5 pages, 1 figur
Perivascular adipose tissue (PVAT) in atherosclerosis: a double-edged sword
Abstract
Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the vasculature, has emerged as an active component of the blood vessel wall regulating vascular homeostasis and affecting the pathogenesis of atherosclerosis. Although PVAT characteristics resemble both brown and white adipose tissues, recent evidence suggests that PVAT develops from its own distinct precursors implying a closer link between PVAT and vascular system. Under physiological conditions, PVAT has potent anti-atherogenic properties mediated by its ability to secrete various biologically active factors that induce non-shivering thermogenesis and metabolize fatty acids. In contrast, under pathological conditions (mainly obesity), PVAT becomes dysfunctional, loses its thermogenic capacity and secretes pro-inflammatory adipokines that induce endothelial dysfunction and infiltration of inflammatory cells, promoting atherosclerosis development. Since PVAT plays crucial roles in regulating key steps of atherosclerosis development, it may constitute a novel therapeutic target for the prevention and treatment of atherosclerosis. Here, we review the current literature regarding the roles of PVAT in the pathogenesis of atherosclerosis.https://deepblue.lib.umich.edu/bitstream/2027.42/145729/1/12933_2018_Article_777.pd
Dual adaptive training of photonic neural networks
Photonic neural network (PNN) is a remarkable analog artificial intelligence
(AI) accelerator that computes with photons instead of electrons to feature low
latency, high energy efficiency, and high parallelism. However, the existing
training approaches cannot address the extensive accumulation of systematic
errors in large-scale PNNs, resulting in a significant decrease in model
performance in physical systems. Here, we propose dual adaptive training (DAT)
that allows the PNN model to adapt to substantial systematic errors and
preserves its performance during the deployment. By introducing the systematic
error prediction networks with task-similarity joint optimization, DAT achieves
the high similarity mapping between the PNN numerical models and physical
systems and high-accurate gradient calculations during the dual backpropagation
training. We validated the effectiveness of DAT by using diffractive PNNs and
interference-based PNNs on image classification tasks. DAT successfully trained
large-scale PNNs under major systematic errors and preserved the model
classification accuracies comparable to error-free systems. The results further
demonstrated its superior performance over the state-of-the-art in situ
training approaches. DAT provides critical support for constructing large-scale
PNNs to achieve advanced architectures and can be generalized to other types of
AI systems with analog computing errors.Comment: 31 pages, 11 figure
Antidiabetic retinopathy effect of Fufang Danshen Mingmu in rats
Purpose: To investigate the effect of Fufang Danshen Mingmu (FDM) on streptozotocin-induced diabetic retinopathy rats.Methods: Diabetic retinopathy model rats were prepared using a single intraperitoneal injection of a freshly prepared solution of streptozotocin (50 mg/kg). The rats were randomly divided into 6 groups of ten rats each: negative control group, control group, reference group (glibenclamide, 1 mg/kg) as well as FDM groups, (50, 100 and 200 mg/kg body weight). Blood glucose and plasma insulin levels were determined. Oxidative stress was evaluated in liver and kidney as lipid peroxidation (LPO), superoxide dismutase (SOD), reduced glutathione (GSH), glutathione peroxidase (GPx) and catalase (CAT). Blood serum levels of creatinine and urea were determined in both diabetic control and treated rats.Results: Compared with diabetic rats, oral administration of FDM at a dose of 200 mg/kg daily for 30 days resulted in a significant decrease in fasting blood glucose (120.21 ± 3.37 mg/dL, p < 0.05) and increased insulin level (13.31 ± 0.67 uU/mL, p < 0.05). Furthermore, it significantly reduced biochemical parameters (serum creatinine, 0.86 ±0.24 mg/dL, p < 0.05) and serum urea 41.86±1.59 mg/dL, p <0.05).Conclusion: The results indicate that FDM normalizes impaired antioxidant status in streptozotocin induced diabetic retinopathy rats, and also exerts a protective effect against lipid peroxidation by scavenging free radicals
3-Hydroxy-1,2-dimethoxyxanthone
The title compound (systematic name: 3-hydroxy-1,2-dimethoxy-9H-xanthen-9-one), C15H12O5, was isolated from Polygala arillata. The tricyclic unit is essentially planar (r.m.s. deviation = 0.039 Å). In the crystal, the molecules form stacks along the a axis. Intermolecular O—H⋯O hydrogen bonds link the molecules into chains parallel to [010]
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