51 research outputs found

    Re-colonizing spaces of memorializing: the case of the Chattri Indian Memorial, UK

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    This article inspects the ways that spaces of war memorialization are organized and reorganized through official and unofficial meaning-making activities. It aims to contribute to the discussion of the ‘value’ of memorializing by examining a multifaceted space of remembrance and commemoration: the Chattri Indian Memorial built near Brighton, UK. The article brings postcolonial perspectives to explore how memorializing has been organized here, focusing on the activities of once-colonized people and the affective, embodied aspects of organizing practices. Built in 1921 to honour Indian soldiers who fought in WWI, the Chattri evolved from a colonial instrument to symbol and space for ethnic-Indian group activities. The study employed historical, visual and ethnographic methods to study the tangible monument and the changing nature of the memorializing activities carried out around the monument. Memorializing is conceptualized within three inter-related processes: colonizing, de-colonizing and re-colonizing to examine how forms and practices of memorialization constitute a values-laden organizing system

    Wright-Fisher diffusion bridges

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    The trajectory of the frequency of an allele which begins at xx at time 00 and is known to have frequency zz at time TT can be modelled by the bridge process of the Wright-Fisher diffusion. Bridges when x=z=0x=z=0 are particularly interesting because they model the trajectory of the frequency of an allele which appears at a time, then is lost by random drift or mutation after a time TT. The coalescent genealogy back in time of a population in a neutral Wright-Fisher diffusion process is well understood. In this paper we obtain a new interpretation of the coalescent genealogy of the population in a bridge from a time t∈(0,T)t\in (0,T). In a bridge with allele frequencies of 0 at times 0 and TT the coalescence structure is that the population coalesces in two directions from tt to 00 and tt to TT such that there is just one lineage of the allele under consideration at times 00 and TT. The genealogy in Wright-Fisher diffusion bridges with selection is more complex than in the neutral model, but still with the property of the population branching and coalescing in two directions from time t∈(0,T)t\in (0,T). The density of the frequency of an allele at time tt is expressed in a way that shows coalescence in the two directions. A new algorithm for exact simulation of a neutral Wright-Fisher bridge is derived. This follows from knowing the density of the frequency in a bridge and exact simulation from the Wright-Fisher diffusion. The genealogy of the neutral Wright-Fisher bridge is also modelled by branching P\'olya urns, extending a representation in a Wright-Fisher diffusion. This is a new very interesting representation that relates Wright-Fisher bridges to classical urn models in a Bayesian setting. This paper is dedicated to the memory of Paul Joyce

    Polybenzimidazole (PBI) Membranes for Phenol Dehydration via Pervaporation

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    Phenol is an important commodity in chemical industries and dewatering is a critical process in its application. In this work, polybenzimidazole (PBI) membranes with various morphologies are employed for phenol dehydration via pervaporation, including flat-sheet dense membranes, single-layer and dual-layer hollow fiber membranes. Effects of cross-linking modification and post-thermal treatment on the performance of PBI flat-sheet dense membranes were investigated; effects of the operation temperature and feed composition are also studied, not only in terms of flux and separation factor, but also of the intrinsic permeance and selectivity of the membrane. In order to achieve a higher permeation flux, PBI single-layer hollow fiber membranes of thinner selective layers were developed and studied with the effect of different spinning parameters. The preliminary study of dual-layer PBI/PBI and PBI/poly­(vinylidene fluoride) (PVDF) dual-layer hollow fiber membranes are also carried out to explore the potential of high-performance composite membranes for phenol dehydration. The promising separation performance of PBI membranes exhibited via benchmarking shows its great potential for phenol dehydration, and it may open new perspectives for the development of high-performance membranes for the pervaporation dehydration of phenol or other corrosive organics

    The relationships between beginning and ending time of leaf abscission.

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    <p>The relationships between beginning and ending time of leaf abscission.</p

    Correlation analysis of leaf phenological characters of main tree species in urban forest of Shenyang.

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    a<p>The timing for each leaf phenology is indicated by the days since March 1 every year from 2005 to 2009.</p><p>**p<0.01.</p

    Leaf phonological characters of main tree species in urban forest of Shenyang (2005–2009 year).

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    a<p>The timing for each leaf phenology is indicated by the days since March 1 every year from 2005 to 2009.</p

    The relationships between beginning and ending time of leaf emergence.

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    <p>The relationships between beginning and ending time of leaf emergence.</p

    Interface interaction mediated surface plasmon resonance enhancement promoted visible-light-driven CO2 reduction with water

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    The conversion of carbon dioxide (CO2) into fuel using solar energy holds significant promise. However, the inefficient use of light and poor production activity have hindered its development. Here, we propose a simple in situ annealing oxidation method by coating a layer of TiO2 outside TiN, a material with a favorable price and localized surface plasmon resonance (LSPR) effect, to create an L-TiNO composite. The yield of CO over L-TiNO (50.8 ÎŒmol g−1 h−1) is 56.4 times that over TiO2 (0.9 ÎŒmol g−1 h−1) under visible light irradiation in pure aqueous environment, with a selectivity of 95.98%. In-situ Fourier transform infrared (FTIR) measurements reflect the CO2-COOH*-CO conversion route happening on L-TiNO. Characterizations like the Kelvin probe force microscopy (KPFM) technique confirm the generation of built-in electric field, which facilitates efficient carrier separation and migration. Density functional theory (DFT) calculations support that L-TiNO with LSPR effect alters the shape of absorbed CO2 to facilitate generation COOH* via forming hydroxyl end group (Ti-OH) and promotes CO* desorption to CO(g). This work provides valuable insights into the coupling of plasmonic materials with semiconductors to achieve efficient solar energy utilization

    Image_2_Establishment and validation of a ferroptosis-related prognostic signature for hepatocellular carcinoma.tif

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    BackgroundHepatocellular carcinoma (HCC) is the most common type of primary liver cancer with high heterogeneity. The prognosis of HCC is quite poor and the prognostic prediction also has challenges. Ferroptosis is recently recognized as a kind of iron-dependent cell death, which is involved in tumor progression. However, further study is needed to validate the influence of drivers of ferroptosis (DOFs) on the prognosis of HCC.MethodsThe FerrDb database and the Cancer Genome Atlas (TCGA) database were applied to retrieve DOFs and information of HCC patients respectively. HCC patients were randomly divided into training and testing cohorts with a 7:3 ratio. Univariate Cox regression, LASSO and multivariate Cox regression analyses were carried out to identify the optimal prognosis model and calculate the risk score. Then, univariate and multivariate Cox regression analyses were performed to assess the independence of the signature. At last, gene functional, tumor mutation and immune-related analyses were conducted to explore the underlying mechanism. Internal and external databases were used to confirm the results. Finally, the tumor tissue and normal tissue from HCC patients were applied to validate the gene expression in the model.ResultsFive genes were identified to develop as a prognostic signature in the training cohort relying on the comprehensive analysis. Univariate and multivariate Cox regression analyses confirmed that the risk score was able to be an independent factor for the prognosis of HCC patients. Low-risk patients showed better overall survival than high-risk patients. Receiver operating characteristic (ROC) curve analysis confirmed the signature’s predictive capacity. Furthermore, internal and external cohorts were consistent with our results. There was a higher proportion of nTreg cell, Th1 cell, macrophage, exhausted cell and CD8+T cell in the high-risk group. The Tumor Immune Dysfunction and Exclusion (TIDE) score suggested that high-risk patients could respond better to immunotherapy. Besides, the experimental results showed that some genes were differentially expressed between tumor and normal tissues.ConclusionIn summary, the five ferroptosis gene signature showed potential in prognosis of patients with HCC and could also be regarded as a value biomarker for immunotherapy response in these patients.</p
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