9 research outputs found
Integrated geophysical exploration for sulphide minerals in the Wadi Sa'al areasouth SinaiEgypt
Get PDFIntegrated geophysical exploration for sulphide minerals in the Wadi Sa'al area, south Sinai, Egypt
No full textOn the use of gravity and magnetic anomalies for locating probable areas of metallic mineralization in South Sinai, Egypt
No full textLand suitability modeling for newly reclaimed area using GIS-based multi-criteria decision analysis
No full textPredictors of sustained clinical response in patients with Behçet’s disease-related uveitis treated with infliximab and adalimumab
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Role of uranium in controlling radiogenic heat production based on gamma ray spectrometry and thermal remote sensing data, southwestern Sinai, Egypt
No full textTreating inflammation by blocking interleukin-1 in a broad spectrum of diseases.
No full textItem does not contain fulltextInterleukin-1 (IL-1) is a highly active pro-inflammatory cytokine that lowers pain thresholds and damages tissues. Monotherapy blocking IL-1 activity in autoinflammatory syndromes results in a rapid and sustained reduction in disease severity, including reversal of inflammation-mediated loss of sight, hearing and organ function. This approach can therefore be effective in treating common conditions such as post-infarction heart failure, and trials targeting a broad spectrum of new indications are underway. So far, three IL-1-targeted agents have been approved: the IL-1 receptor antagonist anakinra, the soluble decoy receptor rilonacept and the neutralizing monoclonal anti-IL-1beta antibody canakinumab. In addition, a monoclonal antibody directed against the IL-1 receptor and a neutralizing anti-IL-1alpha antibody are in clinical trials
