Application of Data Warehouse and Data Mining in Construction Management

All construction project are constrained by their schedules, budgets and specifications, and safety and environmental regulations. These constraints made construction management more complex and difficult. At the same time, many historical data that can support the decisions in the future are kept in construction enterprises,. To use the historical data effectively and efficiently, it is essential to apply the data warehouse and data mining technologies. This paper introduces a research which aims to develop a data warehouse system according to the requirements of construction enterprises and use data mining technology to learn useful information and knowledge from the data warehouse system. The design, the development and the application of this system are detailedly introduced in this paper

Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity

Aminoacyl-tRNA synthetases (aaRSs) are a family of enzymes responsible for the covalent link of amino acids to their cognate tRNAs. The selectivity and species-specificity in the recognitions of both amino acid and tRNA by aaRSs play a vital role in maintaining the fidelity of protein synthesis. We report here the first crystal structure of human tryptophanyl-tRNA synthetase (hTrpRS) in complex with tRNA(Trp) and Trp which, together with biochemical data, reveals the molecular basis of a novel tRNA binding and recognition mechanism. hTrpRS recognizes the tRNA acceptor arm from the major groove; however, the 3′ end CCA of the tRNA makes a sharp turn to bind at the active site with a deformed conformation. The discriminator base A73 is specifically recognized by an α-helix of the unique N-terminal domain and the anticodon loop by an α-helix insertion of the C-terminal domain. The N-terminal domain appears to be involved in Trp activation, but not essential for tRNA binding and acylation. Structural and sequence comparisons suggest that this novel tRNA binding and recognition mechanism is very likely shared by other archaeal and eukaryotic TrpRSs, but not by bacterial TrpRSs. Our findings provide insights into the molecular basis of tRNA specificity and species-specificity

Capacitive Removal of Heavy Metal Ions from Wastewater via an Electro-Adsorption and Electro-Reaction Coupling Process

Heavy metals widely exist in wastewater, which is a serious threat to human health or water environment. Highly efficient removal of heavy metal ions from wastewater is a major challenge to wastewater treatment. In this work, capacitive removal of heavy metal ions from wastewater via an electro-adsorption and electro-reaction coupling process was originally demonstrated. The removal efficiency of heavy metal ions in the binary-component solutions containing metal nitrate (10 mg/L) and NaCl (100 mg/L) can reach 99%. Even the removal efficiency of heavy metal ions can be close to 99% in the multi-component solution containing all the seven metal nitrates (10 mg/L for each) and 100 mg/L NaCl. Meanwhile, the electro-adsorption and electro-reaction coupling process maintained excellent regeneration ability even after 20 cycles. Furthermore, the heavy metal ions removal mechanism was proven to be the pseudocapacitive intercalation of heavy metal ions into the layered structure of the employed W18O49/graphene in the electro-adsorption and electro-reaction coupling process. This work demonstrates great potential for general applicability to wastewater treatment. </p