Homogeneous and single-side-operational connector mechanism for self-reconfigurable, self-assembly and self-healing systems

Designs of single-end-operative reconfigurable genderless connectors that include a base, a plurality of movable jaws that are formed on the base and can engage to the jaws of another connector, and an actuator that is mounted on the base and can engage and move the jaws of the reconfigurable connector to connect the reconfigurable connector with another connector

Accretion Disc-Jet Couplings in X-ray Binaries

When the matter from a companion star is accreted towards the central compact accretor, i.e. a black hole (BH) or a neutron star (NS), an accretion disc and a jet outflow will form, providing bight X-ray and radio emission, which is known as X-ray binaries (XRBs). In the low/hard state, there exist disc-jet couplings in XRBs, but it remains uncertain whether the jet power comes from the disc or the central accretor. Moreover, BHXRBs have different properties compared with NSXRBs: quiescent BHXRBs are typically two to three orders of magnitude less luminous than NSXRBs in X-ray, whereas BHXRBs are more radio loud than NSXRBs. In observations, an empirical correlation has been established between radio and X-ray luminosity, $L_{\rm R} \propto L_{\rm X}^b$, where $b\sim 0.7$ for BHXRBs and $b \sim 1.4$ for non-pulsating NSXRBs. However, there are some outliers of BHXRBs showing unusually steep correlation as NSXRBs at higher luminosities. In this work, under the assumption that the origin of jet power is related to the internal energy of the inner disc, we apply our magnetized, radiatively efficient thin disc model and the well-known radiatively inefficient accretion flow model to NSXRBs and BHXRBs. We find that the observed radio/X-ray correlations in XRBs can be well understood by the disc-jet couplings.Comment: 8 pages, 3 figures, accepted for publication in MNRA

Spectral tracing of deuterium for imaging glucose metabolism.

Cells and tissues often display pronounced spatial and dynamical metabolic heterogeneity. Common glucose-imaging techniques report glucose uptake or catabolism activity, yet do not trace the functional utilization of glucose-derived anabolic products. Here we report a microscopy technique for the optical imaging, via the spectral tracing of deuterium (STRIDE), of diverse macromolecules derived from glucose. Based on stimulated Raman-scattering imaging, STRIDE visualizes the metabolic dynamics of newly synthesized macromolecules, such as DNA, protein, lipids and glycogen, via the enrichment and distinct spectra of carbon-deuterium bonds transferred from the deuterated glucose precursor. STRIDE can also use spectral differences derived from different glucose isotopologues to visualize temporally separated glucose populations using a pulse-chase protocol. We also show that STRIDE can be used to image glucose metabolism in many mouse tissues, including tumours, brain, intestine and liver, at a detection limit of 10 mM of carbon-deuterium bonds. STRIDE provides a high-resolution and chemically informative assessment of glucose anabolic utilization

SUPERBOT: A Deployable, Multi-Functional, and Modular Self-Reconfigurable Robotic System

Abstract – Self-reconfigurable robots are modular robots that can autonomously change their shape and size to meet specific operational demands. Recently, there has been a great interest in using self-reconfigurable robots in applications such as reconnaissance, rescue missions, and space applications. Designing and controlling self-reconfigurable robots is a difficult task. Hence, the research has primarily been focused on developing systems that can function in a controlled environment. This paper presents a novel self-reconfigurable robotic system called SuperBot, which addresses the challenges of building and controlling deployable self-reconfigurable robots. Six prototype modules have been built and preliminary experimental results demonstrate that SuperBot is a flexible and powerful system that can be used in challenging realworld applications

Live-cell quantitative imaging of proteome degradation by stimulated Raman scattering

Protein degradation is a regulatory process essential to cell viability and its dysfunction is implicated in many diseases, such as aging and neurodegeneration. In this report, stimulated Raman scattering microscopy coupled with metabolic labeling with ^(13)C-phenylalanine is used to visualize protein degradation in living cells with subcellular resolution. We choose the ring breathing modes of endogenous ^(12)C-phenylalanine and incorporated ^(13)C-phenylalanine as protein markers for the original and nascent proteomes, respectively, and the decay of the former wasquantified through ^(12)C/(^(12)C + ^(13)C) ratio maps. We demonstrate time-dependent imaging of proteomic degradation in mammalian cells under steady-state conditions and various perturbations, including oxidative stress, cell differentiation, and huntingtin protein aggregation