A Gravitational Wave Detector with Cosmological Reach

Twenty years ago, construction began on the Laser Interferometer Gravitational-wave Observatory (LIGO). Advanced LIGO, with a factor of ten better design sensitivity than Initial LIGO, will begin taking data this year, and should soon make detections a monthly occurrence. While Advanced LIGO promises to make first detections of gravitational waves from the nearby universe, an additional factor of ten increase in sensitivity would put exciting science targets within reach by providing observations of binary black hole inspirals throughout most of the history of star formation, and high signal to noise observations of nearby events. Design studies for future detectors to date rely on significant technological advances that are futuristic and risky. In this paper we propose a different direction. We resurrect the idea of a using longer arm lengths coupled with largely proven technologies. Since the major noise sources that limit gravitational wave detectors do not scale trivially with the length of the detector, we study their impact and find that 40~km arm lengths are nearly optimal, and can incorporate currently available technologies to detect gravitational wave sources at cosmological distances $(z \gtrsim 7)$

Characterization of systematic error in Advanced LIGO calibration

The raw outputs of the detectors within the Advanced Laser Interferometer Gravitational-Wave Observatory need to be calibrated in order to produce the estimate of the dimensionless strain used for astrophysical analyses. The two detectors have been upgraded since the second observing run and finished the year-long third observing run. Understanding, accounting, and/or compensating for the complex-valued response of each part of the upgraded detectors improves the overall accuracy of the estimated detector response to gravitational waves. We describe improved understanding and methods used to quantify the response of each detector, with a dedicated effort to define all places where systematic error plays a role. We use the detectors as they stand in the first half (six months) of the third observing run to demonstrate how each identified systematic error impacts the estimated strain and constrain the statistical uncertainty therein. For this time period, we estimate the upper limit on systematic error and associated uncertainty to be $< 7\%$ in magnitude and $< 4$ deg in phase ($68\%$ confidence interval) in the most sensitive frequency band 20-2000 Hz. The systematic error alone is estimated at levels of $< 2\%$ in magnitude and $< 2$ deg in phase

Approaching the motional ground state of a 10 kg object

The motion of a mechanical object -- even a human-sized object -- should be governed by the rules of quantum mechanics. Coaxing them into a quantum state is, however, difficult: the thermal environment masks any quantum signature of the object's motion. Indeed, the thermal environment also masks effects of proposed modifications of quantum mechanics at large mass scales. We prepare the center-of-mass motion of a 10 kg mechanical oscillator in a state with an average phonon occupation of 10.8. The reduction in temperature, from room temperature to 77 nK, is commensurate with an 11 orders-of-magnitude suppression of quantum back-action by feedback -- and a 13 orders-of-magnitude increase in the mass of an object prepared close to its motional ground state. This begets the possibility of probing gravity on massive quantum systems.Comment: published version containing minor change

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M&gt;70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0&lt;e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Sensitivity improvement of a LIGO gravitational Wayne detector through squeezed state injection

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 2013.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Title as it appears in MIT Commencement Exercises program, June 2013: Sensitivity improvement of a LIGO gravitational Wayne detector through squeezed state injection. Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (p. 217-223).Direct detection of gravitational waves will require earth based detectors to measure strains of the order 10-21, at frequencies of 100 Hz, a sensitivity that has been accomplished with the initial generation of LIGO interferometric gravitational wave detectors. A new generation of detectors currently under construction is designed improve on the sensitivity of the initial detectors by about a factor of 10. The quantum nature of light will limit the sensitivity of these Advanced LIGO interferometers at most frequencies; new approaches to reducing the quantum noise will be needed to improve the sensitivity further. This quantum noise originates from the vacuum fluctuations that enter the unused port of the interferometer and interfere with the laser light. Vacuum fluctuations have the minimum noise allowed by Heisenberg's uncertainty principle, [Delta]X1 [Delta]X2 >/=1, where the two quadratures X1 and X2 are non-commuting observables responsible for the two forms of quantum noise, shot noise and radiation pressure noise. By replacing the vacuum fluctuations entering the interferometer with squeezed states, which have lower noise in one quadrature than the vacuum state, we have reduced the shot noise of a LIGO interferometer. The sensitivity to gravitational waves measured during this experiment represents the best sensitivity achieved to date at frequencies above 200 Hz, and possibly the first time that squeezing has been measured in an interferometer at frequencies below 700 Hz. The possibility that injection of squeezed states could introduce environmental noise couplings that would degrade the crucial but fragile low frequency sensitivity of a LIGO interferometer has been a major concern in planning to implement squeezing as part of baseline interferometer operations. These results demonstrate that squeezing is compatible with the low frequency sensitivity of a full scale gravitational wave interferometer. We also investigated the limits to the level of squeezing observed, including optical losses and fluctuations of the squeezing angle. The lessons learned should allow for responsible planning to implement squeezing in Advanced LIGO, either as an alternative to high power operation or an early upgrade to improve the sensitivity. This thesis is available at DSpace@MIT and has LIGO document number P1300006.by Sheila E Dwyer.Ph.D