From Web 1.0 to Web 2.0 and back - How did your Grandma use to tag?

We consider the applicability of terms extracted from anchortext as a source of Web page descriptions in the form of tags. With a relatively simple and easy-to-use method, we show that anchortext significantly overlaps with tags obtained from the popular tagging portal del.icio.us. Considering the size and diversity of the user community potentially involved in social tagging, this observation is rather surprising. Furthermore, we show by an evaluation using human-created relevance assessments the general suitability of the anchortext tag generation in terms of user-perceived precision values. The awareness of this easy-to-obtain source of tags could trigger the rise of new tagging portals pushed by this automatic bootstrapping process or be applied in already existing portals to increase the number of tags per page by merely looking at the anchortext which exists anyway

Rheumatoid arthritis - treatment: 180. Utility of Body Weight Classified Low-Dose Leflunomide in Japanese Rheumatoid Arthritis

Background: In Japan, more than 20 rheumatoid arthritis (RA) patients died of interstitial pneumonia (IP) caused by leflunomide (LEF) were reported, but many of them were considered as the victims of opportunistic infection currently. In this paper, efficacy and safety of low-dose LEF classified by body weight (BW) were studied. Methods: Fifty-nine RA patients were started to administrate LEF from July 2007 to July 2009. Among them, 25 patients were excluded because of the combination with tacrolimus, and medication modification within 3 months before LEF. Remaining 34 RA patients administered 20 to 50 mg/week of LEF were followed up for 1 year and enrolled in this study. Dose of LEF was classified by BW (50 mg/week for over 50 kg, 40 mg/week for 40 to 50 kg and 20 to 30 mg/week for under 40 kg). The average age and RA duration of enrolled patients were 55.5 years old and 10.2 years. Prednisolone (PSL), methotrexate (MTX) and etanercept were used in 23, 28 and 2 patients, respectively. In case of insufficient response or adverse effect, dosage change or discontinuance of LEF were considered. Failure was defined as dosages up of PSL and MTX, or dosages down or discontinuance of LEF. Last observation carried forward method was used for the evaluation of failed patients at 1 year. Results: At 1 year after LEF start, good/ moderate/ no response assessed by the European League Against Rheumatism (EULAR) response criteria using Disease Activity Score, including a 28-joint count (DAS28)-C reactive protein (CRP) were showed in 14/ 10/ 10 patients, respectively. The dosage changes of LEF at 1 year were dosage up: 10, same dosage: 5, dosage down: 8 and discontinuance: 11 patients. The survival rate of patients in this study was 23.5% (24 patients failed) but actual LEF continuous rate was 67.6% (11 patients discontinued) at 1 year. The major reason of failure was liver dysfunction, and pneumocystis pneumonia was occurred in 1 patient resulted in full recovery. One patient died of sepsis caused by decubitus ulcer infection. DAS28-CRP score was decreased from 3.9 to 2.7 significantly. Although CRP was decreased from 1.50 to 0.93 mg/dl, it wasn't significant. Matrix metalloproteinase (MMP)-3 was decreased from 220.0 to 174.2 ng/ml significantly. Glutamate pyruvate transaminase (GPT) was increased from 19 to 35 U/l and number of leukocyte was decreased from 7832 to 6271 significantly. DAS28-CRP, CRP, and MMP-3 were improved significantly with MTX, although they weren't without MTX. Increase of GPT and leukopenia were seen significantly with MTX, although they weren't without MTX. Conclusions: It was reported that the risks of IP caused by LEF in Japanese RA patients were past IP history, loading dose administration and low BW. Addition of low-dose LEF is a potent safe alternative for the patients showing unsatisfactory response to current medicines, but need to pay attention for liver function and infection caused by leukopenia, especially with MTX. Disclosure statement: The authors have declared no conflicts of interes

Correction to: Cluster identification, selection, and description in Cluster randomized crossover trials: the PREP-IT trials

An amendment to this paper has been published and can be accessed via the original article

Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

An Interactive Map of Semantic Web Ontology Usage

Publishing information on the Semantic Web using common formats enables data to be linked together, integrated and reused. In order to fully leverage the potential for interlinking data by reusing existing schemas, an intuitive way of viewing current usage of RDF vocabularies is required. We present a system which allows a user to view the most frequently occurring namespaces and classes in a large Semantic Web dataset, and the main linkage patterns that exist between them. Users can select a namespace of interest in order to examine usage of a particular ontology, and see how it is being combined with other vocabularies

Understanding online communities by using semantic web technologies

During the last few years, the Web that we used to know as a read-only medium shifted to a read-write Web, often known as Web 2.0 or the Social Web, in which people interact, share and build content collaboratively within online communities. In order to clearly understand how these online communities are formed, evolve, share and produce content, a first requirement is to gather related data. In this chapter, we give an overview of how Semantic Web technologies can be used to provide a unified layer of representation for Social Web data in an open and machine-readable manner thanks to common models and shared semantics, facilitating data gathering and analysis. Through a comprehensive state of the art review, we describe the various models that can be applied to online communities and give an overview of some of the new possibilities offered by such a layer in terms of data querying and community analysis.The work presented in this chapter has been funded in part by Science Foundation Ireland under Grant No. SFI/08/CE/I1380 (Líon 2). We would also like to acknowledge the winners of the SIOC data competition whose entries were referenced in this chapter, as well as Eyal Oren and Benjamin Heitmann for their work on the SIOC Explorer.Not peer reviewe