19 research outputs found

    Understanding patient options, utilization patterns, and burdens associated with breast cancer screening.

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    Abstract Despite ongoing awareness, educational campaigns, and advances in technology, breast cancer screening remains a complex topic for women and for the health care system. Lack of consensus among organizations developing screening guidelines has caused confusion for patients and providers. The psychosocial factors related to breast cancer screening are not well understood. The prevailing algorithm for screening results in significant rates of patient recall for further diagnostic imaging or procedures, the majority of which rule out breast cancer rather than confirming it. For women, the consequences of the status quo range from unnecessary stress to additional out-of-pocket expenses to indirect costs that are more difficult to quantify. A more thoughtful approach to breast cancer screening, coupled with a research agenda that recognizes the indirect and intangible costs that women bear, is needed to improve cost and quality outcomes in this area

    Journal Of Mass Spectrometry

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    this paper, we report methods utilizing MALDI time-of-flight (TOF) MS in combination with exonuclease digestion and PSD to identify the location and chemical structure of DNA adducts formed by the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a defined sequence ODN. PhIP is a heterocyclic amine formed during the cooking of protein-rich foods such as beef, chicken and fis

    A sermon, preached at the ordination of the Rev. Jonathan Whitaker [electronic resource] : to the pastoral care of the church and society in Sharon, Massachusetts, February 27, 1799. By Abiel Holmes, A.M. Pastor of the First Church in Cambridge.

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    Half-title: Mr. Holmes' sermon."The charge: by the Rev. Mr. Cushing, of Waltham."--p. [37]-40."The right hand of fellowship: by the Rev. Mr. Howard, of Canton."--p. [41]-49.Signatures: [A]p4s B-Fp4s [G]p2s ([G]1 verso, [G]2 blank)Evans,Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library

    Practical guide for the use of medical evidence in scientific publication: recommendations for the medical student: narrative review

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    Actualmente, la adaptación de la evidencia científica en la resolución de problemas clínicos se basa en el método de la medicina basada en la evidencia. Los estudiantes de medicina y los profesionales de la salud deben tener un conocimiento adecuado de este método y así brindar una adecuada atención en salud y cada vez más brindar publicaciones científicas de alta calidad que puedan ser posteriormente integradas en diferentes escenarios clínicos. Se han propuesto varias escalas y herramientas como guías para reconocer los diferentes niveles de calidad de la evidencia disponible, sus grados de recomendación y los sesgos y falacias que pueden ocurrir tanto en el ámbito clínico como en el de investigación, con el objetivo de identificar la mejor evidencia disponible. . Sin embargo, pocos estudiantes y profesionales los conocen y hacen un uso adecuado de ellos. Por lo tanto, es necesario sintetizar estas herramientas de manera comprensible y práctica.Currently, the adaptation of scientific evidence in clinical problem solving is based on the evidence-based medicine method. Medical students and health professionals should have an adequate knowledge of this method and thus provide adequate health care and increasingly provide high quality scientific publications that can be subsequently integrated in different clinical scenarios. Several scales and tools have been proposed as guides to recognize the different levels of quality of the available evidence, their degrees of recommendation and the biases and fallacies that may occur both in the clinical and research areas, with the aim of identifying the best available evidence. However, few students and professionals are aware of them and make proper use of them. Therefore, it is necessary to synthesize these tools in an understandable and practical way
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