94 research outputs found

    Investment Attitude of Working Women: A Study of Education Sector in Punjab

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    Investment is important for improving productivity and increasing the competitiveness of an economy. The present paper is an attempt to explore the factors influencing the investment attitude of women working in the education sector in the Punjab State in India. Even though, general profile of women investors is changing in tune with time, but they are insulating in various spheres of investment such as awareness and preference of investment. Today, the role of women has changed from “Savers to Investors”. Factor Analytical results revealed that women investors prefer to invest in risk free securities. The level of financial knowledge also influences their investment attitude. The present study reveals the factors namely; secure investment avenues, financial literacy, stock market investment and post office schemes, bank deposits, physical assets, risk taking ability and concern for financial matters that are important to women working in education sector

    Simulation of Planar Inverted F Antenna for On-Body and free space Communication

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    The expansion of recent wireless communications devices has put significant Compression on the antenna performance, as the size of the device has decreased in parallel to the increase in the number of communications systems supported by a single terminal. The Body Area Network (BAN) helps constant monitoring of Human health with updates of medical records through Internet. In this paper, we propose an on-body and free space performance of Planar Inverted F antenna which operates in Industrial scientific and Medical (ISM) frequency band at 2.45 GHz. The planar inverted –F antenna is popular for portable wireless devices because of its low profile, small size, and built-in structure This antenna is designed to achieve better Specific absorption rate. Other field parameters like Gain, Directivity, Return loss and Radiation have been evaluated on the body and on free space antenna with FEM based software HFSS ver. 13.0

    Secure Cloud Architecture for Preserving Privacy in Cloud Computing Using OTP/WTP

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    The main objective of the proposed architecture is preserving the privacy of the information ensuring that this information cannot be misused. In this paper we have proposed secure cloud architecture to address the user privacy problem in a cloud. By using OTP and WTP in cloud computing system, our proposed architecture achieves better goal of preserving the privacy of a user

    A PHARMACOLOGICAL COMPREHENSIVE REVIEW ON ‘RASSBHARY' PHYSALIS ANGULATA (L.)

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    The present review article reveals the importance of species Physalis angulata (L.) of the genus Physalis (L.) distributed worldwide including India. Physalis species are perennial, erect and variously having toothed or lobed leaves. Physalis angulata (L.) belongs to the family Solanaceae, includes about 120 species with different and specific herbal characters. On the basis of these herbal characters, the plant is traditionally used as medicine to cure various disorders like asthma, kidney, bladder, jaundice, gout, inflammations, cancer, digestive problems and diabetes etc. P. angulata is a source of the variety of phytoconstituents like phytosteroles, withangulatin A, a variety of physalins and flavonol glycoside etc. The plant extracts from the different parts having different pharmacological activities such as anti-cancerous, immunomodulatory, anti-diabetic, diuretic and anti-bacterial. In this article cytomorphological, phytochemical, biological activities and ethnobotanical inputs have been extensively recorded for P. angulata (L.)

    Effects of calcium channel blocker, nifedipine, on antidepressant activity of fluvoxamine, venlafaxine and tianeptine in mice

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    Background: Cardiovascular diseases are commonly associated with depression. Calcium channel blockers (CCBs) form commonly used group of drugs for the treatment of a number of cardiovascular diseases. Nifedipine, a CCB, has been shown to possess antidepressant activity and potentiate antidepressant activity of imipramine and sertraline, however, literature on its interaction with newer antidepressant drugs such as fluvoxamine, venlafaxine and tianeptine is limited. Hence, the present study was undertaken.Methods: The study was carried out in albino mice in two phases. In Phase I, antidepressant activity of nifedipine, fluvoxamine, venlafaxine and tianeptine were confirmed after their single dose administration using forced swim test (FST) and tail suspension test (TST) and their minimum antidepressant doses were determined. In Phase II, the effect of nifedipine on antidepressant activity of fluvoxamine, venlafaxine and tianeptine was studied by orally administering sub-antidepressant doses of these drugs for 28 days. FST and TST were carried out on 1st, 14th and 28th day of the study and change in immobility period was observed.Results: In Phase I, all the studied drugs exhibited dose dependent antidepressant activity in both FST and TST. Minimal antidepressant dose of nifedipine, fluvoxamine, venlafaxine and tianeptine was observed as 10, 25, 25 and 10 mg/kg respectively. In Phase II, combinations of sub-antidepressant dose of nifedipine (5 mg/kg) with sub-antidepressant doses of fluvoxamine (12.5 mg/kg), venlafaxine (12.5 mg/kg) and tianeptine (5 mg/kg) exhibited enhanced antidepressant activity when compared to the control group and individual drug groups after same duration of treatment.Conclusions: Nifedipine, fluvoxamine, venlafaxine and tianeptine possess antidepressant activity and nifedipine exhibits synergistic antidepressant activity with fluvoxamine, venlafaxine and tianeptine

    Comparison of drug advertisements published in Indian and foreign journals

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    Background: Drug advertisements form one of the major sources for updating drug information by the medical professionals. It has been observed that Indian drug advertisements provide incomplete and poor quality of essential information. However, existing information on comparison of drug advertisements in Indian and foreign journals is limited. Hence, this study was planned to compare the drug advertisements published in Indian and foreign journals.Methods: A total of 200 drug advertisements, 100 each from Indian and foreign journals, were randomly selected excluding those of medical devices, surgical appliances, nutritional supplements and ayurvedic drugs. The drug advertisements from two sources were compared for drug groups, compliance to ‘Ethical criteria for medicinal drug promotion’ of World Health Organization (WHO), retrievability of cited reference(s) and mention of any additional information.Results: Drug groups advertised frequently in the Indian journals were those used for chronic diseases whereas chemotherapeutic agents topped the list in foreign journals. Brand names were mentioned in 100% advertisements in both categories of journals whereas information on other ingredients known to cause problems was not mentioned in any of the studied advertisements. Overall, compliance to WHO guidelines by advertisements was 54.6% in Indian journals and 68.2% in foreign journals. The two categories of journals didn’t differ significantly in retrievability of cited reference(s) and additional information except for information on drug storage which was significantly more mentioned in Indian journals.Conclusions: Drug advertisements in both Indian and foreign journals were incomplete for updating drug information by medical professionals.

    Segmentation of Kidney Tumor

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    Medical Image Segmentation is a routine task in various clinical settings. There is a great interest in understanding the morphology of different human organs healthy or diseased. Until fairly recently, this task was done manually by clinical experts requiring years of difficult training tailored to specific medical fields. In this article we present a fully autonomous Machine Learning based method to segment Kidney and Tumor from human abdominal CT scans. Manually annotated data (210 datasets) were provided as a part of the Kits2109 MICCAI grandchallenge

    Thousands of Lesions in Disseminated Cysticercosis

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    Effect of tianeptine on seizure threshold and anticonvulsant activity of valproate, phenobarbitone and phenytoin in mice

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    Background: Depression is a common psychiatric comorbidity in patients with epilepsy and often remains untreated due to concern of antidepressant induced seizures. Tricyclic antidepressants, norepinephrine reuptake inhibitors and bupropion have been shown to increase the risk of seizures. Selective serotonin reuptake inhibitors and venlafaxine have shown both anticonvulsant and proconvulsant activity. The information on anticonvulsant effects of tianeptine, a newer antidepressant, is limited to few animal studies. In view of this, the present study was undertaken to investigate the anticonvulsant activity of tianeptine and its interaction with conventional antiepileptic drugs (AEDs) viz. valproate, phenobarbitone and phenytoin in mice.Methods: The study was carried out in 3 phases using healthy adult male mice. In phase I, effect of oral administration of tianeptine on seizure threshold was studied using electroconvulsive threshold method. In phase II and phase III, effect of tianeptine on median effective dose (ED50) of valproate, phenobarbitone and phenytoin was studied using maximal electroshock seizure (MES) test after administering tianeptine with these AEDs in various combinations. In phase II, drugs were administered orally once while in phase III, these were daily administered orally for 28 days.Results: In phase I, tianeptine increased electroconvulsive threshold in dose dependent manner but effect was significant only at 20 and 40 mg/kg (P<0.05 and 0.001 respectively). In phase II and III, tianeptine exhibited dose dependent reduction in ED50 of all the studied AEDs, however, significant reduction of ED50 of valproate and phenobarbitone (P<0.05 for both) was observed only when tianeptine was administered at 40 mg/kg, while significant reductions in ED50 of phenytoin were observed when tianeptine was administered as 20 and 40 mg/kg (P<0.05 and 0.01 respectively) and in phase III, significant reduction of ED50 value of valproate (P<0.01) and phenobarbitone (P<0.05) was observed with tianeptine at 40 mg/kg while reduction in ED50 of phenytoin was significant at all the studied doses of tianeptine with P<0.05 at 10 and 20 mg/kg and P<0.01 at 40mg/kg..Conclusions: Tianeptine exhibits anticonvulsant action which is synergistic with anticonvulsant effects of valproate, phenobarbitone and phenytoin suggesting that tianeptine may be a safe option in patients of epilepsy concurrently suffering from depression
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