146 research outputs found

    Health and safety in an organisation

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    Health and Safety of employees are of utmost importance for the performance of both the employees and the organisation. The main aim of this research project is to study the health and safety issues existing within an organisation. Qualitative observation methodology was adopted for gathering relevant and appropriate information. Under this method, self-knowledge was implemented and observation of the workplace conducted to identify different issues that can influence the health and safety of workers and the consumers which the organisation serves. Failure to wear personal protective equipment like gloves, shoes, cap, eyeglasses; failure to follow hygiene practices, for instance, leaving the sauce bottle open, are observed to be different issues. Based on these results, it is recommended that the organisation develops a sound health and safety policy, provides proper training to the staff, implements health-related work policies, monitors the practices adopted by the employees, and provides personal protective equipment to employees

    Low-power STDR CMOS sensor for locating faults in aging aircraft wiring

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    Journal ArticleA CMOS sensor used to locate intermittent faults on live aircraft wires is presented. A novel architecture was developed to implement the Sequence Time Domain Reflectometry method on a 0.5- m integrated circuit. The sensor locates short or open circuits on active wires with an accuracy of +/-1 ft when running at a clock speed of 100 MHz. A novel algorithm is proposed that utilizes the shape of the correlation peak to account for sub-bit delay, thus increasing the accuracy of fault location. The power consumed by the microchip is 39.9 mW

    RE-Tagger: A light-weight Real-Estate Image Classifier

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    Real-estate image tagging is one of the essential use-cases to save efforts involved in manual annotation and enhance the user experience. This paper proposes an end-to-end pipeline (referred to as RE-Tagger) for the real-estate image classification problem. We present a two-stage transfer learning approach using custom InceptionV3 architecture to classify images into different categories (i.e., bedroom, bathroom, kitchen, balcony, hall, and others). Finally, we released the application as REST API hosted as a web application running on 2 cores machine with 2 GB RAM. The demo video is available here.Comment: European Conference on Machine Learning and Principles and Practice of Knowledge Discovery in Databases (DEMO TRACK

    Low-power STDR CMOS sensor for locating faults in aging aircraft wiring

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    Journal ArticleA CMOS sensor used to locate intermittent faults on live aircraft wires is presented. A novel architecture was developed to implement the Sequence Time Domain Reflectometry method on a 0.5- m integrated circuit. The sensor locates short or open circuits on active wires with an accuracy of +/-1 ft when running at a clock speed of 100 MHz. A novel algorithm is proposed that utilizes the shape of the correlation peak to account for sub-bit delay, thus increasing the accuracy of fault location. The power consumed by the microchip is 39.9 mW

    TETRACYCLINE: A USEFUL CLASS OF ANTIBIOTICS FOR SUCCESSFUL ENDODONTICS

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    Antibiotics have been used frequently in treatment of odontogenic infections. However in endodontic diseases, the source of infection is rarely eliminated by the use of antimicrobial drugs alone. The mainstay of treating pulpal and periapical infections remains the cleaning and debridement of root canal system. Topical antibacterial agents can be used as an adjunct in the form of an irrigant or intracanal medicament during endodontic therapy. Most often employed antibiotic in endodontics is tetracycline class of drugs. Research has shown that tetracycline agents have various beneficial properties apart from bacteriostatic action, including antiresorptive activity, ability to remove smear layer from canal surface after cleaning and shaping. They also show the property of substantivity which prolongs their effect by allowing slow gradual release over time. Therefore, the present paper aims to outline the possible applications of tetracycline drugs in endodontics

    Contextual Multilingual Spellchecker for User Queries

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    Spellchecking is one of the most fundamental and widely used search features. Correcting incorrectly spelled user queries not only enhances the user experience but is expected by the user. However, most widely available spellchecking solutions are either lower accuracy than state-of-the-art solutions or too slow to be used for search use cases where latency is a key requirement. Furthermore, most innovative recent architectures focus on English and are not trained in a multilingual fashion and are trained for spell correction in longer text, which is a different paradigm from spell correction for user queries, where context is sparse (most queries are 1-2 words long). Finally, since most enterprises have unique vocabularies such as product names, off-the-shelf spelling solutions fall short of users' needs. In this work, we build a multilingual spellchecker that is extremely fast and scalable and that adapts its vocabulary and hence speller output based on a specific product's needs. Furthermore, our speller out-performs general purpose spellers by a wide margin on in-domain datasets. Our multilingual speller is used in search in Adobe products, powering autocomplete in various applications

    A proteomic atlas of senescence-associated secretomes for aging biomarker development.

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    The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions, ranging from neurodegeneration to cancer. The complexity of the SASP, typically assessed by a few dozen secreted proteins, has been greatly underestimated, and a small set of factors cannot explain the diverse phenotypes it produces in vivo. Here, we present the "SASP Atlas," a comprehensive proteomic database of soluble proteins and exosomal cargo SASP factors originating from multiple senescence inducers and cell types. Each profile consists of hundreds of largely distinct proteins but also includes a subset of proteins elevated in all SASPs. Our analyses identify several candidate biomarkers of cellular senescence that overlap with aging markers in human plasma, including Growth/differentiation factor 15 (GDF15), stanniocalcin 1 (STC1), and serine protease inhibitors (SERPINs), which significantly correlated with age in plasma from a human cohort, the Baltimore Longitudinal Study of Aging (BLSA). Our findings will facilitate the identification of proteins characteristic of senescence-associated phenotypes and catalog potential senescence biomarkers to assess the burden, originating stimulus, and tissue of origin of senescent cells in vivo

    Utilization of Amul Dairy effluent for agriculture practices

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    ABSTRACT Pot experiments were conducted to evaluate the impact of Amul dairy effluent on certain physico-chemical properties of soil and on growth, and quality of Lady's finger (Abelomoschus esculentus) and Guar (Cymopsis tetragonoloba.). The effluent used in different concentration 20%, 40%, 60%, 80% and 100%. The pH of the waste water was near about neutral but it contained an enough amount of nitrogen, phosphate, chloride, calcium, carbonates, bicarbonates and suspended and dissolved solids when compared with fresh water. Soil receiving the waste water showed no significant changes in water soluble salts, electrical conductivity, cation exchange capacity, pH, total organic carbon etc. Moreover, waste water irrigation resulted in increased growth and nutrients of both the crops

    Hormonal and non-hormonal oral contraceptives given long-term to pubertal rats differently affect bone mass, quality and metabolism

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    IntroductionWe investigated the effects of hormonal and non-hormonal oral contraceptives (OCs) on bone mass, mineralization, composition, mechanical properties, and metabolites in pubertal female SD rats.MethodsOCs were given for 3-, and 7 months at human equivalent doses. The combined hormonal contraceptive (CHC) was ethinyl estradiol and progestin, whereas the non-hormonal contraceptive (NHC) was ormeloxifene. MicroCT was used to assess bone microarchitecture and BMD. Bone formation and mineralization were assessed by static and dynamic histomorphometry. The 3-point bending test, nanoindentation, FTIR, and cyclic reference point indentation (cRPI) measured the changes in bone strength and material composition. Bone and serum metabolomes were studied to identify potential biomarkers of drug efficacy and safety and gain insight into the underlying mechanisms of action of the OCs.ResultsNHC increased bone mass in the femur metaphysis after 3 months, but the gain was lost after 7 months. After 7 months, both OCs decreased bone mass and deteriorated trabecular microarchitecture in the femur metaphysis and lumbar spine. Also, both OCs decreased the mineral: matrix ratio and increased the unmineralized matrix after 7 months. After 3 months, the OCs increased carbonate: phosphate and carbonate: amide I ratios, indicating a disordered hydroxyapatite crystal structure susceptible to resorption, but these changes mostly reversed after 7 months, indicating that the early changes contributed to demineralization at the later time. In the femur 3-point bending test, CHC reduced energy storage, resilience, and ultimate stress, indicating increased susceptibility to micro-damage and fracture, while NHC only decreased energy storage. In the cyclic loading test, both OCs decreased creep indentation distance, but CHC increased the average unloading slope, implying decreased microdamage risk and improved deformation resistance by the OCs. Thus, reduced bone mineralization by the OCs appears to affect bone mechanical properties under static loading, but not its cyclic loading ability. When compared to an age-matched control, after 7 months, CHC affected 24 metabolic pathways in bone and 9 in serum, whereas NHC altered 17 in bone and none in serum. 6 metabolites were common between the serum and bone of CHC rats, suggesting their potential as biomarkers of bone health in women taking CHC.ConclusionBoth OCs have adverse effects on various skeletal parameters, with CHC having a greater negative impact on bone strength
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