First principles calculation of lithium-phosphorus co-doped diamond

We calculate the density of states (DOS) and the Mulliken population of the diamond and the co-doped diamonds with different concentrations of lithium (Li) and phosphorus (P) by the method of the density functional theory, and analyze the bonding situations of the Li-P co-doped diamond thin films and the impacts of the Li-P co-doping on the diamond conductivities. The results show that the Li-P atoms can promote the split of the diamond energy band near the Fermi level, and improve the electron conductivities of the Li-P co-doped diamond thin films, or even make the Li-P co-doped diamond from semiconductor to conductor. The effect of Li-P co-doping concentration on the orbital charge distributions, bond lengths and bond populations is analyzed. The Li atom may promote the split of the energy band near the Fermi level as well as may favorably regulate the diamond lattice distortion and expansion caused by the P atom.Comment: 14 pages, 11 figure

Identification of a novel TSC2 c.3610G > A, p.G1204R mutation contribute to aberrant splicing in a patient with classical tuberous sclerosis complex: a case report

Background: Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by hamartomas in any organ systems. Mutations in the TSC1 or TSC2 gene lead to the dysfunction of hamartin or tuberin proteins, which cause tuberous sclerosis complex. Case presentation: We describe the clinical characteristics of patients from a Chinese family with tuberous sclerosis complex and analyze the functional consequences of their causal genetic mutations. A novel heterozygous mutation (c.3610G > A) at the last nucleotide of exon 29 in TSC2 was identified. On the protein level, this variant was presumed to be a missense mutation (p.Gly1204Arg). However, the splicing assay revealed that this mutation also leads to the whole TSC2 exon 29 skipping, besides the wild-type transcript. The mutated transcript results in an in-frame deletion of 71 amino acids (p.Gly1133_Thr1203del) and its ratio with the normal splice product is of about 44:56. Conclusions: The novel c.3610G > A TSC2 mutation was identified in association with tuberous sclerosis complex. And it was proven to code both for a missense-carrying transcript (56%), and for an isoform lacking exon 29 (44%)

Effect of hot rolling temperature on microstructures and textures of grain oriented silicon steel

The effect of hot rolling temperature on microstructures and textures of grain oriented silicon steel was studied by optical microscopy (OM), zeiss ultra 55 Scanning electron microscope (SEM) and Electron backscatter diffraction (EBSD) technique respectively. The results show that being hot rolled at 1 152 °C and 1 227 °C respectively, the effect of hot rolling temperature on microstructures of hot rolled and normalized sheets is little, and there is only a small difference in grain size between the samples. Secondary recrystallization is difficult to occur in the medium temperature sample due to the lack of sufficient inhibitors in the sample. The major deformed texture component in center region of hot rolled sheets is {114} which has obviously heredity, and it is more sharp in low temperature sample

Effect of finishing rolling reduction on microstructures and textures of grain oriented silicon steel

The effect of finishing rolling reduction on microstructures and textures of grain oriented silicon steel was researched by optical microscopy, zeiss ultra 55 Scanning Electron Microscope (SEM) and Electron Backscatter Diffraction (EBSD) technique severally. The results show that the grain size of hot rolled sheets and decarburized strips decreases, while the center grain size of the normalized sheet increases with the increase of the finishing rolling reduction. The pearlite content increases with the increase of the finishing rolling reduction after normalization. Compare with the previous research, the effect of finishing rolling reduction on the grain size of primary recrystallization is greater than that of roughing rolling reduction, and large rolling reduction is beneficial to the formation of {110} texture