31 research outputs found
Analyzing Timed Systems Using Tree Automata
Timed systems, such as timed automata, are usually analyzed using their
operational semantics on timed words. The classical region abstraction for
timed automata reduces them to (untimed) finite state automata with the same
time-abstract properties, such as state reachability. We propose a new
technique to analyze such timed systems using finite tree automata instead of
finite word automata. The main idea is to consider timed behaviors as graphs
with matching edges capturing timing constraints. When a family of graphs has
bounded tree-width, they can be interpreted in trees and MSO-definable
properties of such graphs can be checked using tree automata. The technique is
quite general and applies to many timed systems. In this paper, as an example,
we develop the technique on timed pushdown systems, which have recently
received considerable attention. Further, we also demonstrate how we can use it
on timed automata and timed multi-stack pushdown systems (with boundedness
restrictions)
A Unifying Approach to Decide Relations for Timed Automata and their Game Characterization
In this paper we present a unifying approach for deciding various
bisimulations, simulation equivalences and preorders between two timed automata
states. We propose a zone based method for deciding these relations in which we
eliminate an explicit product construction of the region graphs or the zone
graphs as in the classical methods. Our method is also generic and can be used
to decide several timed relations. We also present a game characterization for
these timed relations and show that the game hierarchy reflects the hierarchy
of the timed relations. One can obtain an infinite game hierarchy and thus the
game characterization further indicates the possibility of defining new timed
relations which have not been studied yet. The game characterization also helps
us to come up with a formula which encodes the separation between two states
that are not timed bisimilar. Such distinguishing formulae can also be
generated for many relations other than timed bisimilarity.Comment: In Proceedings EXPRESS/SOS 2013, arXiv:1307.690
Analyzing Timed Systems Using Tree Automata
Timed systems, such as timed automata, are usually analyzed using their operational semantics on timed words. The classical region abstraction for timed automata reduces them to (untimed) finite state automata with the same time-abstract properties, such as state reachability. We propose a new technique to analyze such timed systems using finite tree automata instead of finite word automata. The main idea is to consider timed behaviors as graphs with matching edges capturing timing constraints. Such graphs can be interpreted in trees opening the way to tree automata based techniques which are more powerful than analysis based on word automata. The technique is quite general and applies to many timed systems. In this paper, as an example, we develop the technique on timed pushdown systems, which have recently received considerable attention. Further, we also demonstrate how we can use it on timed automata and timed multi-stack pushdown systems (with boundedness restrictions)
Towards an Efficient Tree Automata Based Technique for Timed Systems
The focus of this paper is the analysis of real-time systems with recursion, through the development of good theoretical techniques which are implementable. Time is modeled using clock variables, and recursion using stacks. Our technique consists of modeling the behaviours of the timed system as graphs, and interpreting these graphs on tree terms by showing a bound on their tree-width. We then build a tree automaton that accepts exactly those tree terms that describe realizable runs of the timed system. The emptiness of the timed system thus boils down to emptiness of a finite tree automaton that accepts these tree terms. This approach helps us in obtaining an optimal complexity, not just in theory (as done in earlier work e.g.[concur16]), but also in going towards an efficient implementation of our technique. To do this, we make several improvements in the theory and exploit these to build a first prototype tool that can analyze timed systems with recursion
Stochastic Timed Games Revisited
Stochastic timed games (STGs), introduced by Bouyer and Forejt, naturally generalize both continuous-time Markov chains and timed automata by providing a partition of the locations between those controlled by two players (Player Box and Player Diamond) with competing objectives and those governed by stochastic laws. Depending on the number of players - 2, 1, or 0 - subclasses of stochastic timed games are often classified as 2 1/2-player, 1 1/2-player, and 1/2-player games where the 1/2 symbolizes the presence of the stochastic "nature" player. For STGs with reachability objectives it is known that 1 1/2-player one-clock STGs are decidable for qualitative objectives, and that 2 1/2-player three-clock STGs are undecidable for quantitative reachability objectives. This paper further refines the gap in this decidability spectrum. We show that quantitative reachability objectives are already undecidable for 1 1/2 player four-clock STGs, and even under the time-bounded restriction for 2 1/2-player five-clock STGs. We also obtain a class of 1 1/2, 2 1/2 player STGs for which the quantitative reachability problem is decidable
Development of sunlight-driven eutectic phase change material nanocomposite for applications in solar water heating
Organic phase change materials (PCMs) have been utilized as latent heat energy storage medium for effective thermal management. In this work, a PCM nanocomposite, consisting of a mixture of two organic PCMs (referred to as eutectic gel PCM) and minimal amount (0.5 wt%) of nanographite (NG) as a supporting material, was prepared. Differential scanning calorimeter was used to determine the melting temperature and latent heat of pristine PCM, paraffin (61.5 °C and 161.5 J/g), eutectic gel PCM (54 °C and 158 J/g) and eutectic gel PCM nanocomposite (53.5 °C and 155 J/g). The prepared PCM nanocomposites exhibited enhanced thermal conductivity and ultrafast thermal charging characteristics. The nanocomposites were employed for two different applications: (i) providing hot water using an indigenously fabricated solar water heating (SWH) system and (ii) solar rechargeable glove that can be rapidly warmed and used. Experimental results on SWH system show that the use of PCM nanocomposites helps to increase the charging rate of PCM while reducing the discharging rate of heat by PCM to water, thus enhancing the maximum utilization of solar energy and hence improving the efficiency of the SWH system. The experimental results on solar rechargeable glove revealed that the glove has the ability to retain the temperature up to 3 hours
Time resolved and temperature dependence of the radiative properties of thiol-capped CdS nanoparticles films
Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin with gemtuzumab ozogamicin improves event-free survival in younger patients with newly diagnosed aml and overall survival in patients with npm1 and flt3 mutations
Purpose
To determine the optimal induction chemotherapy regimen for younger adults with newly diagnosed AML without known adverse risk cytogenetics.
Patients and Methods
One thousand thirty-three patients were randomly assigned to intensified (fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin [FLAG-Ida]) or standard (daunorubicin and Ara-C [DA]) induction chemotherapy, with one or two doses of gemtuzumab ozogamicin (GO). The primary end point was overall survival (OS).
Results
There was no difference in remission rate after two courses between FLAG-Ida + GO and DA + GO (complete remission [CR] + CR with incomplete hematologic recovery 93% v 91%) or in day 60 mortality (4.3% v 4.6%). There was no difference in OS (66% v 63%; P = .41); however, the risk of relapse was lower with FLAG-Ida + GO (24% v 41%; P < .001) and 3-year event-free survival was higher (57% v 45%; P < .001). In patients with an NPM1 mutation (30%), 3-year OS was significantly higher with FLAG-Ida + GO (82% v 64%; P = .005). NPM1 measurable residual disease (MRD) clearance was also greater, with 88% versus 77% becoming MRD-negative in peripheral blood after cycle 2 (P = .02). Three-year OS was also higher in patients with a FLT3 mutation (64% v 54%; P = .047). Fewer transplants were performed in patients receiving FLAG-Ida + GO (238 v 278; P = .02). There was no difference in outcome according to the number of GO doses, although NPM1 MRD clearance was higher with two doses in the DA arm. Patients with core binding factor AML treated with DA and one dose of GO had a 3-year OS of 96% with no survival benefit from FLAG-Ida + GO.
Conclusion
Overall, FLAG-Ida + GO significantly reduced relapse without improving OS. However, exploratory analyses show that patients with NPM1 and FLT3 mutations had substantial improvements in OS. By contrast, in patients with core binding factor AML, outcomes were excellent with DA + GO with no FLAG-Ida benefit