Culturally Responsive Pedagogy: A Model to Level the Playing Field for Black Students in a High Poverty Middle School

Academic failure and achievement gaps plague high-poverty school districts with majority-minority student populations. Culturally responsive pedagogy provides an opportunity for educators to bridge the gap caused by poverty and educational disparities. This applied research aimed to create a culture of teaching and learning that impacted student behavior and growth and proficiency in English Language Arts and math at a high poverty middle school. The eighth-grade teachers and students were exposed to this pilot program to increase teacher capacity in cultural responsiveness and increase student achievement. This applied research study utilized two action plan elements, which included professional development and implementation of culturally responsive pedagogy. Four research questions guided this study. The first question inquired about teachers’ perceptions after receiving the professional development. The second question explored teachers’ usage of culturally responsive teaching strategies and program integration in their lesson plans. The third question examined student behaviors and discipline as a result of program implementation. The fourth question evaluated enCase benchmark growth and proficiency in English language arts and math. In a collaborative effort with stakeholders, the findings of this research study support the need for culturally responsive pedagogy to be utilized as a strategy to improve the success of students in high-poverty schools

Importance of Leptosphaeria biglobosa as a cause of phoma stem canker on winter oilseed rape in the UK

Phoma stem canker is a major disease of oilseed rape in the UK, leading to annual yield losses worth more than £100M. The disease is caused by two closely related species, Leptosphaeria maculans and L. biglobosa. L. maculans is generally considered more damaging, causing stem base canker; L. biglobosa is generally less damaging, causing upper stem lesions. Therefore, previous work has mainly focused on L. maculans and there has been little work on L. biglobosa. This work investigated the contribution of L. biglobosa to stem canker epidemics by assessing the amounts of DNA of L. maculans and L. biglobosa in upper stem lesions or stem base cankers on winter oilseed rape cultivars with different types of resistance against L. mac ulans. Diseased upper stem and stem base samples were collected from nine oilseed rape cultivars in a 2011/2012 field experiment at Rothamsted. The presence of L. maculans or L. biglobosa in each stem sample was detected by speciesspecific PCR. The abundance of L. maculans or L. biglobosa in each stem sample was measured by quantification of L. maculans DNA and L. biglobosa DNA using quantitative PCR (qPCR). The amounts of L. biglobosa DNA were greater than those of L. maculans DNA in both upper stem and stem base samples. These results suggest that the severe upper stem lesions and stem base cankers in the 2011/2012 cropping season were mainly caused by L. biglobosa, suggesting that L. biglobosa can sometimes cause considerable yield loss in the UK. There were differences between cultivars in the amounts of L. maculans DNA and L. biglobosa DNA, with the susceptible cultivar Drakkar having more L. maculans DNA than L. biglobosa DNA while resistant cultivars had less L. maculans DNA than L. biglobosa DNA. These results suggest that L. biglobosa can be an important cause of phoma stem canker on oilseed rape in the UK.Peer reviewedFinal Published versio

Strategies for Raising Low Test Scores of Minority Students

Abstract This project is an in-service professional development to prepare teachers for implementing effective strategies for raising minority test scores on standardized tests. These strategies focus on the development of vocabulary and on students’ self-efficacy. The literature shows that the failure for African American and minority students to be successful on standardized test is likely due to lack of support, resources, and adequate preparation. Furthermore, the literature reveals that most of these tests are probably biased toward these students’ cultural and socioeconomic backgrounds. Studies also show other factors such as stress, stereotyping, depression, and anxiety. Taking into consideration these factors, which constitute real obstacles for African American and culturally and linguistically diverse students, this project focuses on teaching strategies and resources to contribute to resolving the poor performance on standardized tests of these categories of learners

The hepatoprotective capacity of selected natural products from South Africa

Drug-induced liver injury (DILI) is recognized as a significant clinical problem, which may account for up to 50% of all cases of acute liver failure. DILI is initiated by the bioactivation of parent drug molecules to produce chemically reactive metabolites. These reactive intermediates induce mitochondrial dysfunction and oxidative stress leading to glutathione (GSH) depletion and damage to cellular proteins, lipids and nucleic acids, which eventually culminates in necrotic cell death. The principal objective of this study is to establish an in vitro screening platform to identify potential hepatoprotective natural products (plants and mushrooms) from South Africa (SA). Aqueous plant extracts (Cyclopia intermedia, Opuntia ficus indica and Kigelia africana), and aqueous and ethanolic macrofungal extracts (Ganoderma lucidum, Russula capensis, Pleurotus ostreatus and Lenzites elegans) were prepared and screened against HepG2 and VERO cells to assess their safety using Hoechst 33342-PI dual labelling. A drug-induced hepatotoxic model was established, using the dietary supplement menadione (vitamin K3). Hoechst 33342- PI, -CellROX® Orange and -TMRE dual labelling was used for necrosis, oxidative stress and mitochondrial membrane potential depolarization (ΔΨm) detection, respectively. The accuracy of the hepatoprotection model was confirmed through HepG2 cellbased assays (Hoechst 33342- PI, -CellROX® Orange and -TMRE dual labelling) that measured the protective effects of natural products against the menadione-induced toxicity, anti-oxidant assays (DPPH, NO, ORAC, CAPe and FRAP) that measured their anti-oxidant potential and enzyme assays (βglucuronidase, carboxylesterase and CYP450 isoform 3A4) that measured their effects on drug metabolism. Silymarin was used as a positive control for each assay. Menadione displayed significant cell death, increased oxidative stress and decreased ΔΨm at an elevated concentration of 100 μM; confirming the hepatotoxicity model, where necroptosis was suspected to be menadione’s cell death mode. Only ethanolic G. lucidum was cytotoxic. All three aqueous plant extracts demonstrated strong anti-oxidant capacities out of all the tested extracts; where C. intermedia displayed the most promising DPPH, NO, ORAC, CAPe and FRAP activity, followed by aqueous G. lucidum. Aqueous plant and ethanolic macrofungal extracts (C. intermedia, O. ficus indica, K. africana, and ethanolic P. ostreatus, R. capensis) displayed decreased menadione-induced ROS production and protected against menadione-induced ΔΨm depolarization, posing them and aqueous G. lucidum potential therapeutic interventions for DILI. Ethanolic L. elegans demonstrated the highest enzyme inhibition for each assay and presented genotoxicity, ruling it out as a therapeutic strategy against DILI. Together these assays addressed several aspects relating to DILI and hepatoprotection, and served as a good starting point in evaluating the therapeutic value of natural products from South Africa

Business Intelligence Trends: A review of Mobile Business Intelligence

The early stages of Decision Support Systems evolved with the technological improvements and availability of massive amounts of data. The concept of Business Intelligence became apparent along with this evolution which incorporates a range of fields and supports decision making in business organizations. Mobile business intelligence is a popular trend in the domain of business intelligence at present. Business organizations employ mobile business intelligence as an extension to the existing business intelligence systems. This study intends to present a review of mobile business intelligence while addressing its benefits, challenges, and limitations. Moreover, this study provides details of several use cases of the applications of mobile business intelligence discovered in the literature