712 research outputs found
Linking bacterial population dynamics and nutrient removal in the granular sludge biofilm ecosystem engineered for wastewater treatment
Intensive nutrient removal from wastewater in anaerobic-aerobic systems using granular sludge should rely on optimal balances at biofilm and microbial ecology levels. This study targets the impacts of reactor characteristics and fluctuations in operation conditions on nutrient removal and bacterial community structures by means of microbial and numerical ecology methods. The dynamics of both predominant and accompanying populations were investigated with high resolution on temporal and phylogenetic scales in two reactors operated during 5 months with synthetic wastewater. Multivariate analyses highlighted significant correlations from process to microbial scales in the first reactor, whereas nitrification and phosphorus removal might have been affected by oxygen mass transfer limitations with no impact at population level in the second system. The bacterial community continuum of the first reactor was composed of two major antagonistic Accumulibacter-Nitrosomonas-Nitrospira and Competibacter-Cytophaga-Intrasporangiaceae clusters that prevailed under conditions leading to efficient P- (> 95%) and N-removal (> 65%) and altered P- (< 90%) and N-removal (< 60%), respectively. A third cluster independent of performances was dominated by Xanthomonadaceae affiliates that were on average more abundant at 25 °C (31 ± 5%) than at 20 °C (22 ± 4%). Starting from the physiological traits of the numerous phylotypes identified, a conceptual model is proposed as a base for functional analysis in the granular sludge microbiome and for future investigations with complex real wastewate
Reciprocal Recommender System for Learners in Massive Open Online Courses (MOOCs)
Massive open online courses (MOOC) describe platforms where users with
completely different backgrounds subscribe to various courses on offer. MOOC
forums and discussion boards offer learners a medium to communicate with each
other and maximize their learning outcomes. However, oftentimes learners are
hesitant to approach each other for different reasons (being shy, don't know
the right match, etc.). In this paper, we propose a reciprocal recommender
system which matches learners who are mutually interested in, and likely to
communicate with each other based on their profile attributes like age,
location, gender, qualification, interests, etc. We test our algorithm on data
sampled using the publicly available MITx-Harvardx dataset and demonstrate that
both attribute importance and reciprocity play an important role in forming the
final recommendation list of learners. Our approach provides promising results
for such a system to be implemented within an actual MOOC.Comment: 10 pages, accepted as full paper @ ICWL 201
Verification and Control of Partially Observable Probabilistic Real-Time Systems
We propose automated techniques for the verification and control of
probabilistic real-time systems that are only partially observable. To formally
model such systems, we define an extension of probabilistic timed automata in
which local states are partially visible to an observer or controller. We give
a probabilistic temporal logic that can express a range of quantitative
properties of these models, relating to the probability of an event's
occurrence or the expected value of a reward measure. We then propose
techniques to either verify that such a property holds or to synthesise a
controller for the model which makes it true. Our approach is based on an
integer discretisation of the model's dense-time behaviour and a grid-based
abstraction of the uncountable belief space induced by partial observability.
The latter is necessarily approximate since the underlying problem is
undecidable, however we show how both lower and upper bounds on numerical
results can be generated. We illustrate the effectiveness of the approach by
implementing it in the PRISM model checker and applying it to several case
studies, from the domains of computer security and task scheduling
Hidden Markov Models and their Application for Predicting Failure Events
We show how Markov mixed membership models (MMMM) can be used to predict the
degradation of assets. We model the degradation path of individual assets, to
predict overall failure rates. Instead of a separate distribution for each
hidden state, we use hierarchical mixtures of distributions in the exponential
family. In our approach the observation distribution of the states is a finite
mixture distribution of a small set of (simpler) distributions shared across
all states. Using tied-mixture observation distributions offers several
advantages. The mixtures act as a regularization for typically very sparse
problems, and they reduce the computational effort for the learning algorithm
since there are fewer distributions to be found. Using shared mixtures enables
sharing of statistical strength between the Markov states and thus transfer
learning. We determine for individual assets the trade-off between the risk of
failure and extended operating hours by combining a MMMM with a partially
observable Markov decision process (POMDP) to dynamically optimize the policy
for when and how to maintain the asset.Comment: Will be published in the proceedings of ICCS 2020;
@Booklet{EasyChair:3183, author = {Paul Hofmann and Zaid Tashman}, title =
{Hidden Markov Models and their Application for Predicting Failure Events},
howpublished = {EasyChair Preprint no. 3183}, year = {EasyChair, 2020}
Optimal client recommendation for market makers in illiquid financial products
The process of liquidity provision in financial markets can result in
prolonged exposure to illiquid instruments for market makers. In this case,
where a proprietary position is not desired, pro-actively targeting the right
client who is likely to be interested can be an effective means to offset this
position, rather than relying on commensurate interest arising through natural
demand. In this paper, we consider the inference of a client profile for the
purpose of corporate bond recommendation, based on typical recorded information
available to the market maker. Given a historical record of corporate bond
transactions and bond meta-data, we use a topic-modelling analogy to develop a
probabilistic technique for compiling a curated list of client recommendations
for a particular bond that needs to be traded, ranked by probability of
interest. We show that a model based on Latent Dirichlet Allocation offers
promising performance to deliver relevant recommendations for sales traders.Comment: 12 pages, 3 figures, 1 tabl
Reducing Violence and Building Trust: Data to Guide Enforcement of Gun Laws in Baltimore
This report is the product of the Reducing Violence, Building Trust: Data to Guide Gun Law Enforcement in Baltimore project. Researchers from the Johns Hopkins Center for Gun Policy and Research (JHCGPR) collected and analyzed data relevant to the enforcement of laws restricting the possession of firearms by prohibited individuals and unlawful carrying of concealed firearms to provide data-driven recommendations for more fair and effective practices. The project was designed to help inform the response to the dual crises in Baltimore—extraordinarily high rates of gun violence, and gun law enforcement practices that, in some cases, have violated the law and more generally weakened community members' trust in the police
Linking bacterial population dynamics and nutrient removal in the granular sludge biofilm ecosystem engineered for wastewater treatment
Intensive nutrient removal from wastewater in anaerobic–aerobic systems using granular sludge should rely on optimal balances at biofilm and microbial ecology levels. This study targets the impacts of reactor characteristics and fluctuations in operation conditions on nutrient removal and bacterial community structures by means of microbial and numerical ecology methods. The dynamics of both predominant and accompanying populations were investigated with high resolution on temporal and phylogenetic scales in two reactors operated during 5 months with synthetic wastewater. Multivariate analyses highlighted significant correlations from process to microbial scales in the first reactor, whereas nitrification and phosphorus removal might have been affected by oxygen mass transfer limitations with no impact at population level in the second system. The bacterial community continuum of the first reactor was composed of two major antagonistic Accumulibacter-Nitrosomonas-Nitrospira and Competibacter-Cytophaga-Intrasporangiaceae clusters that prevailed under conditions leading to efficient P- (> 95%) and N-removal (> 65%) and altered P- (< 90%) and N-removal (< 60%), respectively. A third cluster independent of performances was dominated by Xanthomonadaceae affiliates that were on average more abundant at 25 °C (31 ± 5%) than at 20 °C (22 ± 4%). Starting from the physiological traits of the numerous phylotypes identified, a conceptual model is proposed as a base for functional analysis in the granular sludge microbiome and for future investigations with complex real wastewater
A Continuous-Time Dynamic Factor Model for Intensive Longitudinal Data Arising from Mobile Health Studies
Intensive longitudinal data (ILD) collected in mobile health (mHealth)
studies contain rich information on multiple outcomes measured frequently over
time that have the potential to capture short-term and long-term dynamics.
Motivated by an mHealth study of smoking cessation in which participants
self-report the intensity of many emotions multiple times per day, we propose a
dynamic factor model that summarizes the ILD as a low-dimensional,
interpretable latent process. This model consists of two submodels: (i) a
measurement submodel -- a factor model -- that summarizes the multivariate
longitudinal outcome as lower-dimensional latent variables and (ii) a
structural submodel -- an Ornstein-Uhlenbeck (OU) stochastic process -- that
captures the temporal dynamics of the multivariate latent process in continuous
time. We derive a closed-form likelihood for the marginal distribution of the
outcome and the computationally-simpler sparse precision matrix for the OU
process. We propose a block coordinate descent algorithm for estimation.
Finally, we apply our method to the mHealth data to summarize the dynamics of
18 different emotions as two latent processes. These latent processes are
interpreted by behavioral scientists as the psychological constructs of
positive and negative affect and are key in understanding vulnerability to
lapsing back to tobacco use among smokers attempting to quit.Comment: Main text is 19 pages with 4 figures and 1 table. Supporting material
is 25 page
Reproducibility of experiments in recommender systems evaluation
© IFIP International Federation for Information Processing 2018 Published by Springer International Publishing AG 2018. All Rights Reserved. Recommender systems evaluation is usually based on predictive accuracy metrics with better scores meaning recommendations of higher quality. However, the comparison of results is becoming increasingly difficult, since there are different recommendation frameworks and different settings in the design and implementation of the experiments. Furthermore, there might be minor differences on algorithm implementation among the different frameworks. In this paper, we compare well known recommendation algorithms, using the same dataset, metrics and overall settings, the results of which point to result differences across frameworks with the exact same settings. Hence, we propose the use of standards that should be followed as guidelines to ensure the replication of experiments and the reproducibility of the results
Vitamin D deficiency in Malawian adults with pulmonary tuberculosis : risk factors and treatment outcomes
The study was supported by a Wellcome Trust (London, UK) Clinical PhD Fellowship awarded to DS (086757/Z/08/A) and the Malawi Liverpool Wellcome Trust (MLW) Core grant from the Wellcome Trust.SETTING: Vitamin D deficiency is common in African adults with tuberculosis (TB), and may be exacerbated by the metabolic effects of anti-tuberculosis drugs and antiretroviral therapy (ART). It is unclear whether vitamin D deficiency influences response to antituberculosis treatment. OBJECTIVES : To describe risk factors for baseline vitamin D deficiency in Malawian adults with pulmonary TB, assess the relationship between serum 25-hydroxy vitamin D (25[OH]D) concentration and treatment response, and evaluate whether the administration of anti-tuberculosis drugs and ART is deleterious to vitamin D status during treatment. DESIGN: A prospective longitudinal cohort study. RESULTS : The median baseline 25(OH)D concentration of the 169 patients (58% human immunodeficiency virus [HIV] infected) recruited was 57 nmol/l; 47 (28%) had vitamin D deficiency (<50 nmol/l). Baseline 25(OH)D concentrations were lower during the cold season (P < 0.001), with food insecurity (P = 0.034) or in patients who consumed alcohol (P = 0.019). No relationship between vitamin D status and anti-tuberculosis treatment response was found. 25(OH)D concentrations increased during anti-tuberculosis treatment, irrespective of HIV status or use of ART. CONCLUSIONS : Vitamin D deficiency is common among TB patients in Malawi, but this does not influence treatment response. Adverse metabolic effects of drug treatment may be compensated by the positive impact of clinical recovery preventing exacerbation of vitamin D deficiency during anti-tuberculosis treatment.Publisher PDFPeer reviewe
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