Constraints on the distance to SGR 1806-20 from HI absorption

The giant flare detected from the magnetar SGR 1806-20 on 2004 December 27 had a fluence more than 100 times higher than the only two other SGR flares ever recorded. Whereas the fluence is independent of distance, an estimate for the luminosity of the burst depends on the source's distance, which has previously been argued to be ~15 kpc. The burst produced a bright radio afterglow, against which Cameron et al. (2005) have measured an HI absorption spectrum. This has been used to propose a revised distance to SGR 1806-20 of between 6.4 and 9.8 kpc. Here we analyze this absorption spectrum, and compare it both to HI emission data from the Southern Galactic Plane Survey and to archival 12-CO survey data. We confirm ~6 kpc, as a likely lower limit on the distance to SGR 1806-20, but argue that it is difficult to place an upper limit on the distance to SGR 1806-20 from the HI data currently available. The previous value of ~15 kpc thus remains the best estimate of the distance to the source.Comment: 3 pages, 1 embedded EPS figure. Added sentences to end of Abstract and Conclusion, clarifying that most likely distance is 15 kpc. ApJ Letters, in pres

Giant Molecular Clouds are More Concentrated to Spiral Arms than Smaller Clouds

From our catalog of Milky Way molecular clouds, created using a temperature thresholding algorithm on the Bell Laboratories 13CO Survey, we have extracted two subsets:(1) Giant Molecular Clouds (GMCs), clouds that are definitely larger than 10^5 solar masses, even if they are at their `near distance', and (2) clouds that are definitely smaller than 10^5 solar masses, even if they are at their `far distance'. The positions and velocities of these clouds are compared to the loci of spiral arms in (l, v) space. The velocity separation of each cloud from the nearest spiral arm is introduced as a `concentration statistic'. Almost all of the GMCs are found near spiral arms. The density of smaller clouds is enhanced near spiral arms, but some clouds (~10%) are unassociated with any spiral arm. The median velocity separation between a GMC and the nearest spiral arm is 3.4+-0.6 km/s, whereas the median separation between smaller clouds and the nearest spiral arm is 5.5+-0.2 km/s.Comment: 11 pages, 3 figure

Space missions to detect the cosmic gravitational-wave background

It is thought that a stochastic background of gravitational waves was produced during the formation of the universe. A great deal could be learned by measuring this Cosmic Gravitational-wave Background (CGB), but detecting the CGB presents a significant technological challenge. The signal strength is expected to be extremely weak, and there will be competition from unresolved astrophysical foregrounds such as white dwarf binaries. Our goal is to identify the most promising approach to detect the CGB. We study the sensitivities that can be reached using both individual, and cross-correlated pairs of space based interferometers. Our main result is a general, coordinate free formalism for calculating the detector response that applies to arbitrary detector configurations. We use this general formalism to identify some promising designs for a GrAvitational Background Interferometer (GABI) mission. Our conclusion is that detecting the CGB is not out of reach.Comment: 22 pages, 7 figures, IOP style, References Adde

Applying Contemporary Management Principles to Implementing and Evaluating Value-Added Pharmacist Services.

Value-added pharmacy services encompass traditional and emerging services provided by pharmacists to individual and entire populations of persons increasingly under the auspices of a public health mandate. The success of value-added pharmacy services is enhanced when they are carried out and assessed using appropriate theory-based paradigms. Many of the more important management theories for pharmacy services consider the servicescape of these services recognizing the uniqueness of each patient and service encounter that vary based upon health needs and myriad other factors. In addition, implementation science principles help ensure the financial viability and sustainability of these services. This commentary reviews some of the foundational management theories and provides a number of examples of these theories that have been applied successfully resulting in a greater prevalence and scope of value-added services being offered

Case report of a bifurcated fibular (lateral) collateral ligament: which band is the dominant one?

Background: The fibular collateral ligament is a permanent and extracapsular ligament of the knee joint. It is located on the lateral aspect of the knee and extends from the lateral epicondyle of the femur to the lateral surface of the head of the fibula. As one of the main knee joint ligaments it is a stabilizer of the posterolateral corner of the knee and resists varus stress. The case report displays the bifurcated variant of the fibular collateral ligament. The aim of this study is to determine which of those bands should be considered dominant.Materials and methods: Classical anatomical dissection was performed on the left knee joint. The fibular collateral ligament was thoroughly cleansed around its origin, distal attachments, and course. Appropriate morphometric measurements were collected.Results: A bifurcated variant of the fibular collateral ligament with inverted proportions of its two bands (main and accessory one) constitutes our findings. It originated on the lateral epicondyle of the femur. Then it divided into two bands (A1 and A2). Band A1 inserted to the head of the fibula. A bony attachment of band A2 was located on the lateral aspect of the lateral condyle of the tibia.Conclusions: Although the fibular collateral ligament is a permanent structure it presents morphological variations. It is important to constantly extend morphological knowledge for all scientists concerned in anatomy

Semiclassical effects in black hole interiors

First-order semiclassical perturbations to the Schwarzschild black hole geometry are studied within the black hole interior. The source of the perturbations is taken to be the vacuum stress-energy of quantized scalar, spinor, and vector fields, evaluated using analytic approximations developed by Page and others (for massless fields) and the DeWitt-Schwinger approximation (for massive fields). Viewing the interior as an anisotropic collapsing cosmology, we find that minimally or conformally coupled scalar fields, and spinor fields, decrease the anisotropy as the singularity is approached, while vector fields increase the anisotropy. In addition, we find that massless fields of all spins, and massive vector fields, strengthen the singularity, while massive scalar and spinor fields tend to slow the growth of curvature.Comment: 29 pages, ReVTeX; 4 ps figure

Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmogenic syndrome characterized by sudden death. There are several genetic forms of CPVT associated with mutations in genes encoding the cardiac ryanodine receptor (RyR2) and its auxiliary proteins including calsequestrin (CASQ2) and calmodulin (CaM). It has been suggested that impairment of the ability of RyR2 to stay closed (ie, refractory) during diastole may be a common mechanism for these diseases. Here, we explore the possibility of engineering CaM variants that normalize abbreviated RyR2 refractoriness for subsequent viral-mediated delivery to alleviate arrhythmias in non-CaM-related CPVT

Rose-Ringed Parakeets

Rose-ringed parakeets (Psittacula krameri; hereafter RRPA; Figure 1) are an invasive species in the United States, present in Alabama, Louisiana, Texas, and Virginia, and with established populations in California, Florida, and Hawaii. They are also the most successful species of invasive parakeet, worldwide. RRPA can cause significant damage to agriculture, including grains, oilseeds, fruits, and ornamental plants. Large flocks of RRPA roost near human infrastructure resulting in concerns about human health and safety (e.g., collisions with aircraft, disease transmission, feces accumulation, and noise complaints). The population growth and spread of RRPA is of conservation concern given the potential impact on native wildlife, spread of invasive plant seeds, and destruction of native plants. RRPA are an agricultural pest with a generalist diet and feeding behaviors that increase the severity of crop damage (Figure 2). RRPA damage corn by feeding on the anthers and pollen of the inflorescence, the tender cob stage, and the milky cob stage up until maturity. RRPA perch on sunflower heads and access the seeds that are hulled prior to consumption. Damage to tree fruits is greater on the top branches compared to the side and bottom branches. RRPA attack stored grains and eat unripe fruit, extending the damage period. RRPA often discard partially-eaten food. Crop damage varies with some fields experiencing more damage due to the timing of crop maturity or location (e.g., field or orchard edges have greater damage than interior). RRPA strip roosting trees (e.g., royal palms in Kauai) of their leaves. A long-term management plan that involves sustained lethal control is necessary to reduce invasive RRPA populations and their damage. In the meantime, the following damage management methods may provide short-term relief from RRPA damage

The Impact of Depression on Patient Outcomes in Hip Arthroscopic Surgery.

Background: Mental health impairments have been shown to negatively affect preoperative self-reported function in patients with various musculoskeletal disorders, including those with femoroacetabular impingement. Hypothesis: Those with symptoms of depression will have lower self-reported function, more pain, and less satisfaction on initial assessment and at 2-year follow-up than those without symptoms of depression. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who were enrolled in a multicenter hip arthroscopic surgery registry and had 2-year outcome data available were included in the study. Patients completed the 12-item International Hip Outcome Tool (iHOT-12), visual analog scale (VAS) for pain, and 12-item Short-Form Health Survey (SF-12) when consenting for surgery. At 2-year follow-up, patients were emailed the iHOT, the VAS, and a rating scale of surgical satisfaction. Initial SF-12 mental component summary (MCS) scores Results: A total of 781 patients achieved the approximate 2-year milestone (mean follow-up, 735 ± 68 days), with 651 (83%) having 2-year outcome data available. There were 434 (67%) female and 217 (33%) male patients, with a mean age of 35.8 ± 13.0 years and a mean body mass index of 25.4 ± 8.8 kg/m Conclusion: A large number of patients who underwent hip arthroscopic surgery presented with symptoms of depression, which negatively affected self-reported function, pain levels, and satisfaction on initial assessment and at 2-year follow-up. Surgeons who perform hip arthroscopic surgery may need to identify the symptoms of depression and be aware of the impact that depression can have on surgical outcomes