Simultaneous estimation of cinnamaldehyde and eugenol in essential oils and traditional and ultrasound-assisted extracts of different species of cinnamon using a sustainable/green HPTLC technique

A wide range of analytical techniques are reported for the determination of cinnamaldehyde (CCHO) and eugenol (EOH) in plant extracts and herbal formulations either alone or in combination. Nevertheless, sustainable/green analytical techniques for the estimation of CCHO and EOH either alone or in combination are scarce in the literature. Accordingly, the present research was carried out to establish a rapid, highly sensitive, and sustainable high-performance thin-layer chromatography (HPTLC) technique for the simultaneous estimation of CCHO and EOH in the traditional and ultrasound-assisted methanolic extracts of Cinnamomum zeylanicum, C. burmannii, and C. cassia and their essential oils. The simultaneous estimation of CCHO and EOH was performed through NP-18 silica gel 60 F254S HPTLC plates. The cyclohexane/ethyl acetate (90:10, v v−1) solvent system was optimized as the mobile phase for the simultaneous estimation of CCHO and EOH. The greenness score of the HPTLC technique was predicted using AGREE software. The entire analysis was carried out at a detection wavelength of 296 nm for CCHO and EOH. The sustainable HPTLC technique was observed as linear in the range 10–2000 ng band−1 for CCHO and EOH. The proposed technique was found to be highly sensitive, rapid, accurate, precise, and robust for the simultaneous estimation of CCHO and EOH. The content of CCHO in traditional methanolic extracts of C. zeylanicum, C. burmannii, and C. cassia was found to be 96.36, 118.49, and 114.18 mg g−1, respectively. However, the content of CCHO in ultrasound-assisted methanolic extracts of C. zeylanicum, C. burmannii, and C. cassia was found to be 111.57, 134.39, and 129.07 mg g−1, respectively. The content of CCHO in essential oils of C. zeylanicum, C. burmannii, and C. cassia was found to be 191.20, 214.24, and 202.09 mg g−1, respectively. The content of EOH in traditional methanolic extracts of C. zeylanicum, C. burmannii, and C. cassia was found to be 73.38, 165.41, and 109.10 mg g−1, respectively. However, the content of EOH in ultrasound-assisted methanolic extracts of C. zeylanicum, C. burmannii, and C. cassia was found to be 87.20, 218.09, and 121.85 mg g−1, respectively. The content of EOH in essential oils of C. zeylanicum, C. burmannii, and C. cassia was found to be 61.26, 79.21, and 69.02 mg g−1, respectively. The amounts of CCHO and EOH were found to be significantly higher in ultrasound-assisted extracts of all species compared to its traditional extraction and hence ultrasound extraction has been proposed as a superior technique for the extraction of CCHO and EOH. The AGREE analytical score of the present analytical technique was predicted as 0.75, suggesting excellent greenness profile of the proposed analytical technique. Based on all these observations and results, the proposed sustainable HPTLC technique can be successfully used for the simultaneous estimation of CCHO and EOH in different plant extracts and herbal products

Efficient Broadcasting for Route Discovery in Mobile Ad-hoc Networks

Broadcasting is used in on-demand routing protocols to discover routes in Mobile Ad-hoc Networks (MANETs). On-demand routing protocols, such as AODV (Ad-hoc On-demand Distance Vector) routing, commonly employ pure flooding based broadcasting. However, pure flooding generates excessively redundant routing traffic that may lead to broadcast storm problem (BSP) and deteriorate the performance of MANETs significantly. Probabilistic broadcasting schemes were proposed in the literature to address BSP. However, these schemes do not consider thermal noise and interference which exist in real life MANETs, and therefore, do not perform well in real life MANETs. This paper presents a novel Channel Adaptive Probabilistic Broadcast (CAPB) scheme to disseminate RREQ packets efficiently. The proposed CAPB scheme determines the probability of rebroadcasting RREQ packets on the fly according to the current SINR (Signal to Interference plus Noise Ratio) and node density in the neighborhood. The proposed scheme and two related state of the art (SoA) schemes from the literature ( [1] and [2]) are implemented in the standard AODV routing protocol to replace the pure flooding based broadcast. Simulation results show that the proposed scheme outperforms the standard AODV and the two competitors in terms of routing overhead, throughput and end-to-end delay significantly

DEVELOPMENT OF HEAVY OIL HYDROCRACKING CATALYSTS

This paper present some results obtained from the research program being pursued at the Research Institute of King Fahd University of Petroleum and Minerals aimed at the development of suitable catalysts for hydrocracking of the vacuum gas oils from Arabian Light crude to obtain higher quality distillate products. The newly developed high-performance hydroprocessing catalysts are based on synthetic smectite clays and modified zeolites. Active metals have been incorporated into these novel supports to prepare several catalyst formulations for both stages of the conventional fixed-bed hydrocrackers. These novel catalysts have been characterized by sophisticated techniques and evaluated in different types of reactors (such as Pulse Microreactor, Batch Autoclave reactor, Fixed-bed Flow reactor etc.) using different feedstocks (e.g. model compounds and real VGO). Some of the formulations of developed catalysts have exhibited high performance in terms of hydrodesulfurization and cracking activities when compared to commercial catalysts under the same operating conditions. These catalysts are being further developed, comprehensively characterized, and thoroughly evaluated in order to come up with tailor-made catalyst formulations for hydrocracking of heavy petroleum fractions

Green marketing practices and green consumer behavior: demographic differences among young consumers

The research was undertaken to study the influence of demographics, especially gender, age, education, and income, on the green purchase decisions of Indian consumers. The structured close-ended questionnaire was distributed among millennials (graduate, post-graduate, and doctorate students) in educational institutions in the UT of Jammu and Kashmir. A total of 700 students participated in this study employing stratified random sampling. ANOVA and t-tests were used to analyze the data. The study results show that education and income significantly influence while Age and gender do not significantly influence the green consumer behavior of young Indian consumers. The insights in this study will be helpful to green marketers as they develop strategies for Indian consumers of various genders, age groups, educational backgrounds, occupations, and socioeconomic levels. Future academics and researchers might adopt this work as a starting point to further explore the idea of green marketing in India

Double-outlet right ventricle: Morphologic demonstration using nuclear magnetic resonance imaging

Sixteen patients with double-outlet right ventricle, aged 1 week to 29 years (median 5 months), were studied with a 1.5 tesla nuclear magnetic resonance (NMR) imaging scanner. Two-dimensional echocardiography was performed in all patients. Thirteen patients underwent angiography, including nine who underwent subsequent surgical correction. Three patients underwent postmortem examination.Small children and infants were scanned inside a 32 cm diameter proton head coil. Multiple 5 mm thick sections separated by 0.5 mm and gated to the patient's electrocardiogram were acquired with a spin-echo sequence and an echo time of 30 ms. A combination of standard and oblique imaging planes was used. Imaging times were <90 min. The NMR images were technically unsuitable in one patient because of excessive motion artifact.In the remaining patients, the diagnosis of double outlet right ventricle was confirmed and correlated with surgical and postmortern findings. The NMR images were particularly valuable in demonstrating the interrelations between the great arteries and the anatomy of the outlet septum and the spatial relations between the ventricular septal defect and the great arteries. Although the atrioventricular (AV) valves were not consistently demonstrated, NMR imaging in two patients identified abnormalities of the mitral valve that were not seen with two-dimensional echocardiography. In one patient who had a superoinferior arrangement of the ventricles, NMR imaging was the most useful imaging technique for demonstrating the anatomy.In patients with double-outlet right ventricle, NMR imaging can provide clinically relevant and accurate morphologic information that may contribute to future improvement in patient management

Eco-friendly dyeing of wool and pashmina fabric using Quercus robur L. (fruit cups) dye and Salix alba L. (wood extract) mordant

Study was conducted to investigate the dyeing potential of Quercus robur L. (fruit cups) dye and Salix alba L. (wood extract) mordant on wool and pashmina fabrics. The experiment was conducted keeping in view the environmental safety by using unutilized plant materials and excluding the usage of chemical agents. The dyeing was carried out individually including and excluding mordant adopting different mordanting methods. The parameters like percent absorption, colour coordinates, colour strength (K/S), relative colour strength and colour fastness with regard to washing, light and rubbing were investigated. The results revealed higher percent absorption of mordanted samples than unmordanted samples. Colour coordinates (L*a*b*, Chroma, hue and ?E) of dyed wool and pashmina fabric exhibited satisfactory results. The colour strength (K/S) and relative colour strength of pashmina fabric recorded higher than wool fabric. The fastness properties to washing, light and rubbing showed satisfactory grades including and excluding natural mordant. However, the grades of mordanted samples were found better than unmordanted samples. The dye and mordant in isolation and in combination showed beautiful colours and shades on selected fabrics with satisfactory retention properties, hence can be utilized commercially for coloration of wool and pashmina fabrics

Hamiltonian path analysis of viral genomes

Cryo-electron microscopy (EM) is undergoing a revolution, enabling the study of viral pathogens in unprecedented detail. The asymmetric EM reconstruction of bacteriophage MS2 at medium resolution (8.7 Å) by Koning et al.1, and the subsequent reconstruction at even higher resolution (3.6 Å) by Dai et al.2 revealed the structures of both the protein shell and the asym- metric genomic RNA and the unique maturation protein (A). It is the start of a wave of such structural data for viruses, and calls for the development of new analytical tools to describe the results. One approach is Hamiltonian path analysis (HPA) that we introduced to describe repeated, sequence-specific contacts between the MS2 genome and its protein shell3. Here, we describe how HPA is consistent with the new structures and, in turn, how it extends our understanding beyond the structural data alone