Analysis of financial technologies as a tool for sustainable development

The organization of the finance area is a challenge for companies in any sector. Balancing costs and income is one of the prerequisites for those looking for better profit margins, but it requires the administration of various aspects that do not always fit into a simple financial equation. Different processes and possibilities need to be explored. As you can see, money is the main character in this section. Here you will find articles on the organization of the income and expenses of your business. Working capital (also called working capital), bank credit, cash flow management and taxes are also topics covered in our practical advice. Some recommendations related to accounting are also presented. All this to help you perfectly control the financial operations of your company. And allow you to adapt the equipment and resources so that finances are in order and can consolidate the results and achievements of the rest of your business

Entrance Port for Na+ and K+ Ions on Na+,K+-ATPase in the Cytoplasmic loop between trans-membrane segments M6 and M7 of the α subunit : proximity of the cytoplasmic segment of the β subunit

Based on the following observations we propose that the cytoplasmic loop between trans-membrane segments M6 and M7 (L6/7) of the α subunit of Na+,K+-ATPase acts as an entrance port for Na+ and K+ ions. 1) In defined conditions chymotrypsin specifically cleaves L6/7 in the M5/M6 fragment of 19-kDa membranes, produced by extensive proteolysis of Na+,K+-ATPase, and in parallel inactivates Rb1 occlusion. 2) Dissociation of the M5/M6 fragment from 19-kDa membranes is prevented either by occluded cations or by competitive antagonists such as Ca²+, Mg²+, La³+, p-xylylene bisguanidinium and m-xylylene bisguanidinium, or 1-bromo- 2,4,6-tris(methylisothiouronium)benzene and 1,3-dibromo-2,4,6-tris (methylisothiouronium)benzene (Br2-TITU³1). 3) Ca²1 ions raise electrophoretic mobility of the M5/M6 fragment but not that of the other fragments of the a subunit. It appears that negatively charged residues in L6/7 recognize either Na+ or K+ ions or the competitive cation antagonists. Na+ and K+ ions are then occluded within trans-membrane segments and can be transported, whereas the cation antagonists are not occluded and block transport at the entrance port. The cytoplasmic segment of the β subunit appears to be close to or contributes to the entrance port, as inferred from the following observations. 1) Specific chymotryptic cleavage of the 16-kDa fragment of the β subunit to 15-kDa at 20°C (Shainskaya, A., and Karlish, S. J. D. (1996) J. Biol. Chem. 271, 10309 10316) markedly reduces affinity for Br2-TITU³+ and for Na+ ions, detected by Na+ occlusion assays or electrogenic Na+ binding, whereas Rb+ occlusion is unchanged. 2) Na+ ions specifically protect the 16-kDa fragment against this chymotryptic cleavage