Biodetection grinder

Work on a biodetection grinder is summarized. It includes development of the prototype grinder, second generation grinder, and the production version of the grinder. Tests showed the particle size distribution was satisfactory and biological evaluation confirmed the tests

Relationships Among the Distribution of Terminal Fields of Sensory Afferent Projections to the Deep layers of the Superior Colliculus within the Cat

While it is well known that the different sensory modalities are primarily represented at separate locations within the central nervous system, there are numerous sites in which information from the different sensory modalities converge. Perhaps the best known structure where inputs from different sensory modalities converge is the superior colliculus. Here, not only are visual, auditory and somatosensory inputs present, but they also form organized representations of auditory and visual space as well a map of the body surface in addition, neurons that receive inputs from more than one sensory modality (i.e. multisensory) are found here in abundance. Although a great deal is known regarding the physiological properties of these multisensory neurons and how these characteristics apply to multisensory neurons elsewhere in the brain, little is known regarding the anatomical basis for multisensory convergence and integration. Therefore, the present study is focused on the following problem: How does the organization of the inputs from different sensory modalities to the deep layers of the superior colliculus relate to the multisensory nature of its constituent neurons

Why Youth Voters Have Lower Participation

The turnout rate for young adults in elections succeeding 1964 has significantly diminished. This derives as a result of the methods that the candidates use to reach out to young voters, the agenda being debated or the political climate at the time accompanied by the feeling of political efficacy. This research project delves into the major reasons behind why there has been a low voter turnout rate, that being under fifty percent of those in this age category, for young adults, those being 18 – 24, in presidential elections. This particularly investigates the reasoning for the 2012 election being such a variation from the norm. This theme is extremely important because voter turn out of certain demographics can drastically shift the outcome of an election, as seen in 2012 where the participation of this demographic was pivotal. The research analyzes data and charts of the voting trends for the last four presidential elections of 2000, 2004, 2008, and 2012, against historical trends as well as analyzes peer-reviewed articles and resources that interpret the information

The impact of COVID-19 on the service of emergency department

(1) Introduction: the COVID-19 pandemic significantly impacted the number and acuity of emergency departments (ED) patients, specifically those with non-COVID-19-related health problems. However, the exact impact of the COVID-19 pandemic on ED services is the subject of comprehensive debate. (2) Aim: to gain insight into the consequences of the first wave of the COVID-19 pandemic based on non-COVID-19 presentations and patient acuity using the Canadian Triage and Acuity Scale (CTAS). (3) Method: in Phase 1, the ED records of one of the main regional non-COVID-19 hospitals in Saudi Arabia were retrospectively audited from August 2020 to February 2021—after the first wave of COVID-19—then compared to information collected for the same period in previous year. Phase 2 included calculating the waiting time to identify delays and issues that may impact the triage effectiveness. (4) Results: a change across all CTAS levels was observed post the 1st wave of COVID-19 pandemic. Specifically, there was an increase in the number of patients presenting as higher acuity (CTAS 1 and 2) and a decrease in patients presenting as lower acuity (CTAS 4 and 5). Longer waiting times for patients presenting to ED were also reported. Specifically, 83% of patients presenting as higher acuity experienced a delay. (5) Conclusion: further studies are required to investigate association between the 1st wave of COVID-19 and patient presentations and/or acuity or patient demand and ED capacity. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

The pattern of Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive epidemiological analysis of data from the Saudi Ministry of Health

Purpose: This study describes the epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia. Patients and methods: Epidemiological analysis was performed on data from all MERS-CoV cases recorded by the Saudi Ministry of Health between June 6, 2013 and May 14, 2014. The frequency of cases and deaths was calculated and adjusted by month, sex, age group, and region. The average monthly temperature and humidity of infected regions throughout the year was also calculated. Results: A total of 425 cases were recorded over the study period. The highest number of cases and deaths occurred between April and May 2014. Disease occurrence among men (260 cases [62%]) was higher than in women (162 cases [38%]), and the case fatality rate was higher for men (52%) than for women (23%). In addition, those in the 45–59 years and ≥60 years age groups were most likely to be infected, and the case fatality rate for these people was higher than for other groups. The highest number of cases and deaths were reported in Riyadh (169 cases; 43 deaths), followed by Jeddah (156 cases; 36 deaths) and the Eastern Region (24 cases; 22 deaths). The highest case fatality rate was in the Eastern Region (92%), followed by Medinah (36%) and Najran (33%). MERS-CoV infection actively causes disease in environments with low relative humidity (<20%) and high temperature (15°C–35°C). Conclusion: MERS-CoV is considered an epidemic in Saudi Arabia. The frequency of cases and deaths is higher among men than women, and those above 45 years of age are most affected. Low relative humidity and high temperature can enhance the spread of this disease in the entire population. Further analytical studies are required to determine the source and mode of infection in Saudi Arabia

Parameters Variation to Estimate Performance Characteristics of 3-Phase Asynchronous Motor

The 3-phase asynchronous squirrel cage motors (SCIM) are main competitor machines placed instead of other motors in the commercial and industrial fields. The stator and rotor material selection and construction topology influence the electrical machine design. The results illustrated with the motor of a 15 KW, variable controlled speed, for the constant frequency of 50 Hz or 60 Hz. The motor parameters created inside the simulation model must be matched with the value of a standard parameter for SCIM to achieve a high dynamic response. This work examines the effect of the parameters variation for synchronous motor on the performance characteristics at starting point and at a load change for different time and speed regions. Changing of the rotor power is taken into consideration, this occurs with dynamic change of the hydraulic pump load from the valve. In the industrial applications, production, and manufacturing, till present there are still struggles to find the most holistic environment of the SCIM to achieve its efficiency at the lowest cost and same time control the motor performance, so we predicted the method of reducing the most effective motor parameters to improve the efficiency. The offline method used the SCIM parameters to calculate the time-varying current, torque, and rotor speed. The results illustrated that this method was fully consistent with the experiment tests and the standard theoretical values. A MATLAB program is used to simulate this study. The simulation model proved the feasibility of the proposed method with encouraging performance

Reproductive outcomes following robotic myomectomy

Background: To assess pregnancy outcomes of patients following robotic myomectomy.Methods: Retrospective chart review was performed of 336 patients following robotic myomectomy at a university hospital from June 2006 to May 2013. Patients were called to obtain delivery outcomes.Results: Three hundred and thirty-six women had the following: mean age of 41.97 +/- 12.3 years (range 24-55), mean BMI of 24.6 +/- 4.96, mean of 3.37 +/- 3.1 fibroids removed (range 1-21), and mean weight of 352.28 +/- 339.56 grams of fibroids removed. Approximately 66.9% (N=250) provided pregnancy outcome data with 119 (47.6%) attempting pregnancy after surgery. Eighty-three (69.7%) achieved a total of 91 pregnancies. Less than half of these patients underwent cesarean section, and no cases of uterine rupture. Eighty-seven patients had known infertility pre-surgery; 22 underwent intrauterine insemination resulting in 12 pregnancies, and 34 underwent in vitro fertilization resulting in 25 pregnancies. A total of 53 (60.9%) of patients with infertility achieved 60 total pregnancies.Conclusions: The fertility rate after robotic myomectomy for patients attempting to conceive (69.7%) and for those with known infertility who continued to attempt pregnancy postoperatively (60.9%) were similar. There was a low incidence of complications associated with pregnancies conceived after robotic myomectomy

Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model.

The recent emergence of the SARS-CoV-2 Omicron variant of concern (VOC) containing a heavily mutated spike protein capable of escaping preexisting immunity identifies a continued need for interventional measures. Molnupiravir (MK-4482), an orally administered nucleoside analog, has demonstrated efficacy against earlier SARS-CoV-2 lineages and was recently approved for SARS-CoV-2 infections in high-risk adults. Here we assessed the efficacy of MK-4482 against the earlier Alpha, Beta and Delta VOCs and Omicron in the hamster COVID-19 model. Omicron replication and associated lung disease in vehicle treated hamsters was reduced compared to the earlier VOCs. MK-4482 treatment inhibited virus replication in the lungs of Alpha, Beta and Delta VOC infected hamsters. Importantly, MK-4482 profoundly inhibited virus replication in the upper and lower respiratory tract of hamsters infected with the Omicron VOC. Consistent with its mutagenic mechanism, MK-4482 treatment had a more pronounced inhibitory effect on infectious titers compared to viral RNA genome load. Histopathologic analysis showed that MK-4482 treatment caused a concomitant reduction in the level of lung disease and viral antigen load in infected hamsters across all VOCs examined. Together, our data indicate the potential of MK-4482 as an effective antiviral against known SARS-CoV-2 VOCs, especially Omicron, and likely future SARS-CoV-2 variants

Effect of Emulsified Asphalt on Expansive Soil Strength and Swelling

Some clay soils classified as extended soils threaten the structures resting on them. Many additives are available to improve the properties of expanded soils. This study tries to investigate the consequences of wetting-drying cycles on the swelling behavior of modified expansive clayey soils under laboratory conditions by modifying expansive clayey soil samples using emulsified asphalt. Five different percentages of emulsified asphalt were used: (2, 4, 6, 8, and 10) %. The natural and treatment soils were tested for classification, specific gravity, compaction characteristics, free swell and swell pressure, consolidation, and compressive strength. The liquid limit and plasticity index have been lowered by adding Emulsified Asphalt. After that, the effects of Emulsified Asphalt on undrained shear strength characteristics (cohesion and friction angle) have been studied. The results revealed that when the emulsified asphalt content was increased to 10%, the swelling pressure and swelling potential decreased by 58 and 78 %, respectively. The swell and shrink improvement factor for the 10% emulsified asphalt addition is always larger than 75%. As the duration of wetting-drying cycles increased, the swelling pressure and swelling potential values were also reduced. The plastic limit, on the other hand, increased as the Emulsified Asphalt content increased. Increasing the amount of Emulsified Asphalt increased the maximum dry unit weight values, whereas the optimum water contents increased. It was concluded that emulsified asphalt stabilization may be useful for expansive clay as it improves compressive shear strength