Exploring synchronization and lift suppression in fluid flow around vibrating cylinder: a parallel CFD and global optimization investigation

In this study, we employ a parallel Computational Fluid Dynamics (CFD) code integrated with the VTDIRECT95 algorithm, a parallel deterministic global optimization method, to conduct global optimization for an oscillating circular cylinder. We conduct numerical simulations for the flow at a Reynolds number of 500 within the parameter range of 0.1≤Ax≤0.3 and 0.5fst≤fex≤2.5fst where Ax represents the inline oscillating amplitude, fex denotes the forcing oscillation frequency, and fst corresponds to the frequency of a stationary cylinder. To enhance computational efficiency, a combination of VTdirect and a CFD solver is utilized to efficiently identify the synchronization region, thereby reducing computational resources. The results reveal a significant reduction in the lift coefficient within the synchronized region compared to unsynchronized regimes. Furthermore, the study delves into the underlying flow physics behind synchronization and lift suppression. By synchronizing the shedding of vortices, their detrimental effects are nullified, resulting in a reduction in lift. Moreover, the research examines the influence of three-dimensional (3-D) flow by comparing 2-D and 3-D simulations at two different Reynolds numbers. It demonstrates that accounting for 3-D effects yields more accurate predictions of fluid behavior. Synchronization maps and root mean square (rms) lift coefficient plots illustrate the impact of Reynolds number and movement frequency on lift suppression. The findings indicate that achieving synchronization in 3-D flow necessitates stronger amplitudes and higher frequencies. At higher Reynolds numbers, the wake structures become unstable, leading to intricate vortical patterns. Consequently, the synchronization curve shifts towards higher amplitudes and frequencies in 3-D simulations. Understanding these phenomena is vital for reducing lift force in practical applications. This research significantly contributes to knowledge regarding synchronization and lift suppression in fluid flow around vibrating cylinders.publishedVersio

DESIGN AND IMPLEMENTATION OF BI-AXIAL SOLAR TRACKER USING ARDUINO

Solar energy is a renewable free source of energy that is inexhaustible and sustainable, unlike fossil fuels that are finite. Research is being performed for the development of more efficient systems by absorbing maximum sun light and converting it into electrical power.The purpose of this work is to make more efficient solar panels for photovoltaic perpendicular rays of the sun throughout the year.This includes the design and implementation of research-based Arduino dual axis solar tracking system. The development of experimental setup is comprised of two parts: hardware and software. During hardware development phase, four light dependent resisters have been installed in “+ shaped “mounting on the top of solar panel. Two DC geared motors have been fixed to rotate the solar panel in mutually perpendicular axis to each other so that the plane of each solar panel remains normal to the incident rays of the sun all the time in a day. Firstly, a code in C language is developed and fed to the microcontroller “Arduino UNO”. The graphical user interface (GUI) is developed in “Lab VIEW” and connected with microcontroller to examinethe real time displacement of solar panel in both axes by the feedback information of LDR sensors. This allows two-axis tracking of solar energy and the solar panel is capable of producing electrical energy with sunlight throughout the whole day.Therefore, average power produced by biaxial solar tracker in a day is 20.98% more than that by simple static system

Design of Anion Exchange Membranes and Electrodialysis Studies for Water Desalination

Anion exchange membranes are highly versatile and nowadays have many applications, ranging from water treatment to sensing materials. The preparation of anion exchange membranes (AEMs) from brominated poly(2,6-dimethyl-1,6-phenylene oxide) (BPPO) and methyl(diphenyl)phosphine (MDPP) for electrodialysis was performed. The physiochemical properties and electrochemical performance of fabricated membranes can be measured by changing MDPP contents in the membrane matrix. The influence of a quaternary phosphonium group associated with the removal of NaCl from water is discussed. The prepared membranes have ion exchange capacities (IEC) 1.09–1.52 mmol/g, water uptake (WR) 17.14%–21.77%, linear expansion ratio (LER) 7.96%–11.86%, tensile strength (TS) 16.66–23.97 MPa and elongation at break (Eb) 485.57%–647.98%. The prepared anion exchange membranes were employed for the electrodialytic removal of 0.1 M NaCl aqueous solution at a constant applied voltage. It is found that the reported membranes could be the promising candidate for NaCl removal via electrodialysi

Factors Predicting Renal Function Outcome after Augmentation Cystoplasty

We determined the cause of renal deterioration after augmentation cystoplasty (AC). Twenty-nine adult patients with refractory bladder dysfunction and who underwent ileocystoplasty from 2004 to 2015 were studied. Patients with a decline in glomerular filtration rate (GFR) after augmentation were reviewed. The primary outcome was to determine the factors that might lead to deterioration of estimated GFR. Median follow-up was 7.0 ± 2.6 years. Significant bladder capacity, end filling pressure, and bladder compliance were achieved from median 114 ± 53.6 to 342.1 ± 68.3 ml ( = .0001), 68.5 ± 19.9 to 28.2 ± 6.9 cm H 2 O ( = .0001), and 3.0 ± 2.1 to 12.8 ± 3.9 ( = .0001), respectively. Renal function remained stable and improved in 22 (76%) patients from median eGFR 135 ± 81.98 to 142.82 ± 94.4 ml/min/1.73 m 2 ( = .160). Significant deterioration was found in 7 (24%) patients from median eGFR 68.25 ± 42 to 36.57 ± 35.33 ( = .001). The causes of renal deterioration were noncompliance to self-catheterization (2 patients), posterior urethral valve/dysplastic kidneys (2 patients), and reflux/infection (2 patients). On multivariate analysis, recurrent pyelonephritis (OR 3.87, = 0.0155) and noncompliance (OR 30.78, = 0.0156) were significant. We concluded that AC is not the cause of progression to end-stage renal disease in patients with renal insufficiency

Sonographic Evaluation of Urinary Tract in Patients with Abnormal Renal Function Tests and Urine Examination

Background: Our study will provide reliable ways to diagnose Urinary tract abnormalities to health care professionals to further evaluate, follow up and  surveillance of the pathology . Materials and methods:A  cross-sectional study included 71 patients  with provisional diagnosis of  Urinary Tract Diseases along with the associated clinical manifestations and study duration is 4 months.Results: Our results  shows that among 71 patients, urinary tract diseases is recorded to be maximum in 40.21(57%)  patients and minimum  to be around 34 (44%). In urine analysis out of  71 patients, creatinine level is increase in (24%),  echogenicity of right kidney was increased in (1.4%)  and bilateral echogenicity was noticed in (17%) . Serum urea level is abnormal in (59.1%), echogencity of right and left kidney is increase in (6%) and (1.4%) respectively. Bilateral echogencity is notice in(28%). Calcium oxalate Crystal level is present  in (28%) and hydronephrosis is increased in (15.4%).Urinary bladder wall thickness is abnormal in (21%) patients, many and fewer Red blood cells present in (20%) and (2.8%) respectively . Pus Cells are increase in (36.6%) , hydronephrosis is noted in (15.4%).Patients have many and fewer pus cells (15.4%) and (17%) respectively.Conclusion: We concluded that  ultrasound parameters with correlation of laboratory tests has significant credibility to detect urinary tract diseases . Keywords: Renal Function Test,Urine analysis, Ultrasound. DOI: 10.7176/JHMN/90-14 Publication date:June 30th 202

Serial population-based serosurveys for COVID-19 in two neighbourhoods of Karachi, Pakistan

Objective: To determine population-based estimates of COVID-19 in a densely populated urban community of Karachi, Pakistan.Methods: Three cross-sectional surveys were conducted in April, June and August in low- and high-transmission neighborhoods. Participants were randomly selected to provide blood for Elecsys® immunoassay for detection of anti-SARS-CoV-2 antibodies. Bayesian regression model was used to estimate seroprevalence after adjusting for the demographic characteristics of each district RESULTS: We enrolled 3005 participants from 623 households. In Phase 2, adjusted seroprevalence was estimated as 8.7% (95% CI 5.1-13.1) and 15.1% (95% CI 9.4 -21.7) in low and high transmission areas respectively, compared to 0.2% (95% CI 0-0.7) and 0.4% (95% CI 0 - 1.3) in Phase 1. In Phase 3, it was 12.8% (95% CI 8.3 - 17.7) and 21.5% (95% CI 15.6-28) in low and high transmission areas, respectively. CRI was 0.31 (95% CI 0.16-0.47) and 0.41(95% CI 0.28-0.52) in low and high transmission neighborhoods respectively in Phase 2. Similar trends were observed in Phase 3. Only 5.4% of participants who tested positive for COVID-19 were symptomatic. IFR was 1.66%, 0.37% and 0.26% in Phases 1, 2 and 3 respectively.Conclusion: Continuing rounds of seroprevalence studies will help us better understand secular trends and extent of infection during the course of the pandemic

Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center

Purpose Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC in children. Methods A retrospective analysis was conducted of 42 patients (31 males; mean age, 14.2±6.2 years) who underwent AC for neurogenic and nonneurogenic bladder dysfunction, with a median 12.0±1.5 years of follow-up. All patients underwent AC using the ileum with or without continent reconstruction. Pre-AC, concurrent, and post-AC procedures and complications were analyzed. Patients who underwent ureterocystoplasty, were lost to follow-up, or had less than 10 years of follow-up were excluded. The primary outcomes were the complication and continence rates, the post-AC linear rate of height and weight gain, and renal function. The Student t-test was used to evaluate between-group differences and the paired t-test was used to evaluate longitudinal changes in measured variables. Results Renal function was stable or improved in 32 of 42 patients (76.2%), with a post-AC continence rate of 88.1%. Thirty patients (71.4%) required 72 procedures post-AC. There was no statistically significant difference in the mean percentile of height (P=0. 212) or weight (P=0.142) of patients in the pre- and post-AC periods. No cases of bladder perforation or malignancy were detected. Conclusions We consider AC to be a safe and effective procedure that does not negatively affect future physical growth, while achieving a good rate of stable renal function. Patients need long-term follow-up to address long-term complications

Oxidative Stress Diminishing Perspectives of Green and Black Tea Polyphenols: A Mechanistic Approach

Polyphenols have credentials to tackle the oxidative stress. Oxidative stress is the imbalance between free radicals production and antioxidant enzymes ability to tackle these radicals resulting the onset various metabolic related disorders. Polyphenols based foods have credential as a shield against these glitches mainly owing to their antioxidant potential. In this context, tea polyphenols have gained paramount attention of scientific community as therapeutic agents for the prevention and treatment of various oxidative stress induce maladies owing to their structural diversity, strong antioxidant ability and capacity to modulate various expression involved in the pathogenesis of these maladies. The notable polyphenols are catechins which are mainly present in green tea and further subdivided into various compounds like ECG, EGC, EGCG which has their unique therapeutic potential. The catechins undergo various structural changes and transformed into theaflavins and thearubigins in the process of black tea formation. These are high molecular weight polyphenols and promising candidates in obesity, diabetes and cancer treatment. Mechanistically, these polyphenols ameliorate oxidative stress by trapping the noxious radicals like superoxide and peroxyl, promote the activity of glutathione, suppressing the malondialdehyde (MDA) activity. The current chapter is an attempt to highlight the therapeutic potential of tea polyphenols

Impact of different levels of zinc and nitrogen on growth, productivity, and quality of aromatic rice cultivated under various irrigation regimes in two districts of Pakistan

Rice is a staple food for more than 50% of the global population and it is one of the most valuable cereal crops. To fulfill the dietary requirement of the ever-growing world population, an increase in per-unit production of rice is direly required. In Pakistan, it stands as the 2nd in consumption after wheat, which is a staple food. A huge gap is observed between yield potential and actual yield of the aromatic rice cultivars at a farmer-field level. The significant limitations responsible for this gap are shortage of irrigation water, inappropriate application of fertilizers, less plant population, deficiency of micronutrients, and improper and poor plant protection measures. A field study was planned to assess the yield response and quality attributes of aromatic rice to three levels of zinc (Zn) and nitrogen (N) under three irrigation regimes (8-, 12-, and 16-acre inches) in the Sheikhupura and Sargodha districts of Pakistan. Irrigation treatments significantly influenced the growth, yield, and quality attributes; however, maximum improvement was observed by the application of irrigation at 12-acre inches. Among the Zn treatments, application of Zn at 10 kg ha–1 was observed to be more responsive to improving the growth and quality parameters of aromatic rice crops. In the case of N treatments, application of N at 140 kg ha–1 produced the maximum total tillers, as well as productive tillers per hill, spikelets per panicle, leaf area index, leaf area duration, crop growth rate, total dry matter, harvest index, kernel length, kernel width, and 1,000-kernel weight. Application of N at 140 kg ha–1 not only improved the growth attributes but also increased the net assimilation rate, photosynthetically active radiation, and radiation use efficiency, with respect to total dry matter and kernel yield. The maximum percentage of normal kernels and minimum percentage of opaque, abortive, and chalky kernels were also recorded by application of N at 140 kg ha–1. The outcomes of current experiments depicted that application of irrigational water, zinc, and nitrogen at 12-acre inches, 10, and 140 kg ha–1, respectively, are responsible to achieve maximum resource utilization efficiency, along with increased yield and quality of rice