Experimental Study of Remote Job Submission and Execution on LRM through Grid Computing Mechanisms

Remote job submission and execution is fundamental requirement of distributed computing done using Cluster computing. However, Cluster computing limits usage within a single organization. Grid computing environment can allow use of resources for remote job execution that are available in other organizations. This paper discusses concepts of batch-job execution using LRM and using Grid. The paper discusses two ways of preparing test Grid computing environment that we use for experimental testing of concepts. This paper presents experimental testing of remote job submission and execution mechanisms through LRM specific way and Grid computing ways. Moreover, the paper also discusses various problems faced while working with Grid computing environment and discusses their trouble-shootings. The understanding and experimental testing presented in this paper would become very useful to researchers who are new to the field of job management in Grid.Comment: Fourth International Conference on Advanced Computing & Communication Technologies (ACCT), 201

Scheduling in Grid Computing Environment

Scheduling in Grid computing has been active area of research since its beginning. However, beginners find very difficult to understand related concepts due to a large learning curve of Grid computing. Thus, there is a need of concise understanding of scheduling in Grid computing area. This paper strives to present concise understanding of scheduling and related understanding of Grid computing system. The paper describes overall picture of Grid computing and discusses important sub-systems that enable Grid computing possible. Moreover, the paper also discusses concepts of resource scheduling and application scheduling and also presents classification of scheduling algorithms. Furthermore, the paper also presents methodology used for evaluating scheduling algorithms including both real system and simulation based approaches. The presented work on scheduling in Grid containing concise understandings of scheduling system, scheduling algorithm, and scheduling methodology would be very useful to users and researchersComment: Fourth International Conference on Advanced Computing & Communication Technologies (ACCT), 201

Comparative Study of Interval Type-2 and Type-1 Fuzzy Genetic and Flower Pollination Algorithms in Optimization of Fuzzy Fractional Order <em>PI^λD^μ </em> Controllers

In this chapter, a comparison between fuzzy genetic optimization algorithm (FGOA) and fuzzy flower pollination optimization algorithm (FFPOA) is bestowed. In extension, the prime parameters of each algorithm adapted using interval type-2 and type-1 fuzzy logic system (FLS) are presented. The key feature of type-2 fuzzy system is alimenting the modeling uncertainty to the algorithms, and hence it is a prime motivation of using interval type-2 fuzzy systems for dynamic parameter adaption. These fuzzy algorithms (type-1 and type-2 fuzzy system versions) are compared with the design of fuzzy control systems used for controlling the dihybrid level control process subject to system component (leak) fault. Simulation results reveal that interval type-2 fuzzy-based FPO algorithm outperforms the results of the type-1 and type-2 fuzzy GO algorithm

EMERGING TRENDS OF PROBIOTICS IN FORMULATION DEVELOPMENT AS A BIOTHERAPEUTICS AGENT

Every being wants to live a healthy life. The increase in the discovery and development of medicines is the provokingdemand of mankind to meet with the increasing and spreading illness of the society. Pharmaceutical Sciences have proved itsworth to meet with the emerging problems with thorough challenges.The concept of probiosis, prebiosis and symbiosis havebeen recently emerged and being implemented in pharmaceutics to develop, design and delivery of probiotic drugs whichcan be administered orally as other medicines with its efficient efficacy and least jeopardy.However with the undergoingtrends of its designing and discovery, the emphasis has been focused on to its bimolecular mode of action. The presentreview work would also emphasize the pros and cons of the probiotic food supplements with the necessity for the inventionof preceding probiotic drugs which would rapidly pounce, quell and substitute the use of probiotic foods. The idea of thisprobiotic drug designing will be salutary to the society and would also meet with the cost

A passive fault-tolerant control strategy for a non-linear system: An application to the two tank conical non-interacting level control system

In practical engineering systems, unknown actuator, sensor or system component faults frequently occur, which results from component and interconnection failures, degrade control performance, system stability, and profitability, and even arise hazardous situation. To avoid abnormal activity like faults and maintain system control performance subject to faults occurring into the system, the Fault-tolerant Control (FTC) is a realistic approach to address the unwanted situation. The two-tank conical system is widely used in chemical and food process industries because of its greater advantages. The non-interacting configuration of the two-tank conical system is highly nonlinear due to its shape and varying area of the tank thought the height of the tank, as a consequence level control of this system is extremely difficult. The paper attributes to design a Passive Fault-tolerant Control Strategy (PFTCS) for a Two-tank conical Non Interacting Level Control System (TTCNILCS) subject to the major system (leak), sensor, and actuator faults with external process disturbances. PFTC will increase system control performance and system stability acceptable level in the presence of sensor, system, and actuator faults. The simulation results demonstrate the proposed PFTC strategy has definite fault tolerant ability against the system and actuator faults also it has good disturbance rejection capability. To verify the efficacy of the proposed PFTC strategy Mean Square Error (MSE) and Root Mean Square Error (RMSE) Integral Absolute Error (IAE) indices are used

Case Reports1. A Late Presentation of Loeys-Dietz Syndrome: Beware of TGFβ Receptor Mutations in Benign Joint Hypermobility

Background: Thoracic aortic aneurysms (TAA) and dissections are not uncommon causes of sudden death in young adults. Loeys-Dietz syndrome (LDS) is a rare, recently described, autosomal dominant, connective tissue disease characterized by aggressive arterial aneurysms, resulting from mutations in the transforming growth factor beta (TGFβ) receptor genes TGFBR1 and TGFBR2. Mean age at death is 26.1 years, most often due to aortic dissection. We report an unusually late presentation of LDS, diagnosed following elective surgery in a female with a long history of joint hypermobility. Methods: A 51-year-old Caucasian lady complained of chest pain and headache following a dural leak from spinal anaesthesia for an elective ankle arthroscopy. CT scan and echocardiography demonstrated a dilated aortic root and significant aortic regurgitation. MRA demonstrated aortic tortuosity, an infrarenal aortic aneurysm and aneurysms in the left renal and right internal mammary arteries. She underwent aortic root repair and aortic valve replacement. She had a background of long-standing joint pains secondary to hypermobility, easy bruising, unusual fracture susceptibility and mild bronchiectasis. She had one healthy child age 32, after which she suffered a uterine prolapse. Examination revealed mild Marfanoid features. Uvula, skin and ophthalmological examination was normal. Results: Fibrillin-1 testing for Marfan syndrome (MFS) was negative. Detection of a c.1270G > C (p.Gly424Arg) TGFBR2 mutation confirmed the diagnosis of LDS. Losartan was started for vascular protection. Conclusions: LDS is a severe inherited vasculopathy that usually presents in childhood. It is characterized by aortic root dilatation and ascending aneurysms. There is a higher risk of aortic dissection compared with MFS. Clinical features overlap with MFS and Ehlers Danlos syndrome Type IV, but differentiating dysmorphogenic features include ocular hypertelorism, bifid uvula and cleft palate. Echocardiography and MRA or CT scanning from head to pelvis is recommended to establish the extent of vascular involvement. Management involves early surgical intervention, including early valve-sparing aortic root replacement, genetic counselling and close monitoring in pregnancy. Despite being caused by loss of function mutations in either TGFβ receptor, paradoxical activation of TGFβ signalling is seen, suggesting that TGFβ antagonism may confer disease modifying effects similar to those observed in MFS. TGFβ antagonism can be achieved with angiotensin antagonists, such as Losartan, which is able to delay aortic aneurysm development in preclinical models and in patients with MFS. Our case emphasizes the importance of timely recognition of vasculopathy syndromes in patients with hypermobility and the need for early surgical intervention. It also highlights their heterogeneity and the potential for late presentation. Disclosures: The authors have declared no conflicts of interes