14 research outputs found

    Description features of pharmacology of the drug Kufestrol in increasing productivity of broiler chicks

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    This scientific article presents the effects of kufestrol, a phytoestrogen drug extracted from the Ferula Kuhistanica plant, on the poultry organism. As a result of the use of Kufestrol drug, effects on the live weight, absolute, average daily growth and food consumption of broiler chicks were determined in the experiments. Morphological (erythrocytes, hemoglobin, leukocyte) and biochemical (total protein, albumin, globulin, calcium, phosphorus, glucose) parameters of the blood of chicks treated with the drug were determined. The information that Kufestrol, used through experiments, has a positive effect on the physiological condition of broiler chicks is cited. As a result of the use of the Kufestrol drug in broiler chickens, their viability was 98%, and meat productivity was 25.8% higher than in control groups

    Syntheses, crystal structures and Hirshfeld surface analysis of 2-(benzylsulfanyl)-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole and 2-[(2-chloro-6-fluorobenzyl)sulfanyl]-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole

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    The title compounds were synthesized by alkylation of 5-[(4-dimethylamino)phenyl]-1,3,4-oxadiazole-2-thiol with benzyl chloride or 2-chloro-6-fluorobenzyl chloride in the presence of potassium carbonate. The yields of 2-(benzylsulfanyl)-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole, C17H17N3OS (I), and 2-[(2-chloro-6-fluorobenzyl)sulfanyl]-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole, C17H15ClFN3OS (II), were 96 and 92%, respectively. In the crystal structures of (I) and (II), C–H...π interactions are observed between neighboring molecules. Hirshfeld surface analysis indicates that H...H and H...C/C...H interactions make the most important contributions to the crystal packing

    Synthesis of 2-chloro-n-(3-hydroxyphenyl) Acetamide and 2-chloro-n-(4-hydroxyphenyl) Acetamide and Study of Their Antimicrobial Activity

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    In this work, the results of chloroacetylation of m- and p-aminophenols in the presence of acetic acid, acetonitrile and tetrahydrofuran as a solvent were presented. Methods of purification of the obtained substances were described. The structure of synthesized substances is established by methods of IR, PMR, mass spectroscopy. The antibacterial and antifungal activities of these compounds were investigated. The results of the screening revealed that the compounds showed the appreciable antibacterial activity against Gram-positive and Gram-negative bacteria, whereas compounds did not exhibit any potential antifungal activity
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