AlSi system influence on characteristics of power diodes

La grande variabilità del sistema Al-Si è causa di diversi problemi all’interno di linee di produzione. La stabilità, la prevedibilità, e il controllo di processi e fenomeni è una condizione cardine all’interno delle produzioni di massa che ne prevedono l’impiego. La creazione di un quadro teorico complessivo entro cui inserire i comportamenti del sistema in esame è vitale per poter raggiungere l’obiettivo di avere elevate e consistenti rese produttive

Nutrigenomic activity of plant derived compounds in health and disease: Results of a dietary intervention study in dog

The study was conducted to investigate the effects of dietary administrations of four nutraceuticals in dogs. Seventy four dogswere enrolled in the trials, 24 healthy dogs were fedwith a control diet (CT) and the experimental groups received for 60 days the same diet supplemented with nutraceuticals, namely Echinacea angustifolia (EA, 0.10 mg/kg live weight as echinacoside; 14 dogs), Vaccinium myrtillus (VM, 0.20 mg/kg live weight as anthocyanidin, 13 dogs), Curcuma longa (CL, 6.60 mg/kg live weight as curcumin, 18 dogs with arthrosis), and Sylibum marianum (SM, 1.5 mg/kg live weight as sylibin, 8 dogs with hepatopathy). Dogs were weighted at the beginning of study and blood samples were collected at the beginning (T0) and at the end (T60) of the study. VM significantly down regulated TNF, CXCL8, NFKB1 and PTGS2 and decreased plasma ceruloplasmin (CuCp). The activity of EA was evidenced by the significant decrease of TNF and NFKB1 expression and CuCp levels and by the increase of plasma Zn. Administration of CL caused a significant decrease of CuCp and increase of Zn and a down regulation of TNF, CXCL8, NFKB1 and PTGS2, corroborating the anti-inflammatory action of curcuminoids. After 60 days of treatmentwith SM, plasma ALT/GPT activitywas reduced and paraoxonase was increased, supporting the antioxidant activity of silymarin, also confirmed by the significant up regulation of SOD2. Results indicated that nutraceutical administrations in dogs can be an interesting approach to modulate immune response in order to improve health condition of animals

Activity of plant wastes on acute phase proteins in cows

The effect of two patented protected plants wastes (PW), named in the paper as PE and CO, has been evaluated in dairy heifers under ACTH challenge. The experimental protocol used for each compound involved 3 groups of 5 heifers, 18 days of adaptation to the experimental diets and 5 days (22-26) of ACTH treatment (0.5 mg of Synachten \u2013 Novartis - twice a day). In addition to the basal diet, 1 kg of a mixture of dehy beet pulp and PW in the ratio of 1.0:0.0 (EXP-0), 0.1:0.9 (EXP-1) and 0.3:0.7 (EXP-2) was fed in the morning meal to the experimental groups. Blood was sampled before (days 19 and 22) and during (days 24 and 26) ACTH treatment and analysed for cortisol, glucose, ceruloplasmin and haptoglobin. Acute phase proteins increased in the EXP-1 group for PE (P<0.01) and in EXP-2 group for CO (P<0.05), while the higher concentration of CO reduced haptoglobin concentration (P=0.01). These results suggest that the efficacy of PW integration is dose dependent and the optimal dose seems to be different between the 2 selected compounds

Test Conditions for Pipeline Materials Selection with High Pressure Sour Gas

Acid gases, such as CO2, H2S, and/or sulfur in oil industry's production fluids, can be responsible for both general and localized corrosion, acting with different mechanisms, which depend on chemical and physical properties of the produced fluids. Materials selection for handling such fluids is performed by combining experience with suggestions from standards and regulations. A good deal of knowledge is available to predict corrosion rates for CO2-containing hydrocarbons, but the effect of high H2S pressure is less understood, mainly due to the difficulty of performing laboratory tests in such challenging conditions. For instance, the so-called NACE solution to assess SSC (Sulfide Stress Cracking) susceptibility of steels is a water-based solution simulating production fluids in equilibrium with one bar bubbling H2S gas. This solution does not represent environments where high gas pressure is present. Moreover, it does not take into account the corrosive properties of sulfur and its compounds that may deposit in such conditions. Besides, properties of high pressure gases are intermediate between those of a gas and those of a liquid: high pressure gases have superior wetting properties and better penetration in small pores, with respect to liquids. These features could enhance and accelerate damage, and nowadays such conditions are likely to be present in many production fields. This paper is aimed to point out a few challenges in dealing with high pressure gases and to suggest that, for materials selection in sour service, a better correspondence of test conditions with the actual field conditions shall be pursued

Factors Affecting Gut Microbiota of Puppies from Birth to Weaning

The review described the most important factors affecting the development of the intestinal microbiota in puppies from birth to weaning. The health and well-being of the microbiome in puppies is influenced by the type of parturition, the maternal microbiota, and the diet of the mother, directly or indirectly. The isolation of bacteria in dogs from the placenta, fetal fluids, and fetuses suggests that colonization could occur before birth, although this is still a matter of debate. Accordingly, newborn puppies could harbor bacteria that could be of maternal origin and that could influence microbial colonization later in life. However, the long-term impacts on health and the clinical significance of this transfer is not yet clear and needs to be investigated. The same maternal bacteria were found in puppies that were born vaginally and in those delivered via cesarean section. Potentially, the relationship between the type of parturition and the colonization of the microbiome will influence the occurrence of diseases, since it can modulate the gut microbiome during early life. In addition, puppies’ gut microbiota becomes progressively more similar to adult dogs at weaning, as a consequence of the transition from milk to solid food that works together with behavioral factors. A number of researches have investigated the effects of diet on the gut microbiota of dogs, revealing that dietary interference may affect the microbial composition and activity through the production of short-chain fatty acids and vitamins. These compounds play a fundamental role during the development of the fetus and the initial growth of the puppy. The composition of the diet fed during pregnancy to the bitches is also an important factor to consider for the health of newborns. As far as it is known, the effects of the type of parturition, the maternal microbiota, and the diet on the microbial colonization and the long-term health of the dogs deserve further studies. Definitely, longitudinal studies with a larger number of dogs will be required to assess a causal link between microbiome composition in puppies and diseases in adult dogs

Ricordo di Ivos Margoni

Cinquantotto anni fa, dopo l’esame di maturità, ai primi di novembre capitai al Palazzo dei Cavalieri di Santo Stefano a Pisa, per sostenerne un altro, anche più impegnativo del primo. Il palazzo è la sede centrale della più famosa Università italiana, la «Scuola Normale Superiore». Di essa non avevo molte informazioni. Ero stato rimorchiato lì da due compagni di liceo, nella speranza di vincere il concorso e di riuscire a laurearmi senza spesa, visto che in casa mia quattrini da spendere per..

PROJETO ÉTICO-POLÍTICO DO SERVIÇO SOCIAL E SEUS REBATIMENTOS NA PROFISSÃO

O Serviço Social no Brasil dispõe de um projeto ético-político (PEP) fruto de um amadurecimento profissional e luta política e, neste sentido, entender em que contexto este projeto foi construído e o que representa para a profissão se faz determinante em tempos de regressão de direitos. Desta forma, este artigo tem como objetivo analisar o entendimento dos profissionais sobre o PEP, bem como seus rebatimentos na profissão e sua materialização no cotidiano dos profissionais que o operam nas mais diversas situações cotidianas. Entretanto, foram entrevistadas três Assistentes Sociais, sendo que duas atuam na Política de Assistência Social de um município de pequeno porte e uma Assistente Social em entidade filantrópica, que, com suas experiências, contribuirão para a reflexão deste assunto

A technique to screen plant extracts for anti-inflammatory activity on ovine neutrophils

The effect of two patented protected plants wastes (PW), named in the paper as PE and CO, has been evaluated in dairy heifers under ACTH challenge. The experimental protocol used for each compound involved 3 groups of 5 heifers, 18 days of adaptation to the experimental diets and 5 days (22-26) of ACTH treatment (0.5 mg of Synachten \u2013 Novartis - twice a day). In addition to the basal diet, 1 kg of a mixture of dehy beet pulp and PW in the ratio of 1.0:0.0 (EXP-0), 0.1:0.9 (EXP-1) and 0.3:0.7 (EXP-2) was fed in the morning meal to the experimental groups. Blood was sampled before (days 19 and 22) and during (days 24 and 26) ACTH treatment and analysed for cortisol, glucose, ceruloplasmin and haptoglobin. Acute phase proteins increased in the EXP-1 group for PE (P<0.01) and in EXP-2 group for CO (P<0.05), while the higher concentration of CO reduced haptoglobin concentration (P=0.01). These results suggest that the efficacy of PW integration is dose dependent and the optimal dose seems to be different between the 2 selected compounds

Effect of different starch sources in a raw meat-based diet on fecal microbiome in dogs housed in a shelter

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