1,004 research outputs found
JOINT MOMENTS DURING INSTEP KICKS IN FOOTBALL PLAYERS WITH AND WITHOUT PREVIOUS GROIN PAIN
This study examined how previous groin pain and approach angle affects stance leg and lumbar moments during instep kicks. Male football players with and without previous groin pain (n=11, and n=10) performed instep kicks from 45° and 60° angles while kinetic and kinematic data were recorded (1000Hz and 500Hz respectively). 3D stance leg net joint moments of the hip, knee, and ankle were calculated at peak swing knee flexion and ball contact and the sagittal L5/S1 joint moment was examined throughout the kick. Foot speed at ball contact indicated performance. Players with previous groin pain had lower moments during the kick compared to uninjured controls, but there was no difference in performance. This suggests that the players with previous groin pain utilized an aberrant kicking pattern that offloads certain joints but may cause compensations elsewhere in the kinetic chain
Costamere protein expression and tissue composition of rotator cuff muscle after tendon release in sheep
Previous studies suggested that degradation of contractile tissue requires cleavage of the costamere, a structural protein complex that holds sarcomeres in place. This study examined if costamere turnover is affected by a rotator cuff tear in a previously established ovine model. We found the activity of focal adhesion kinase (FAK), a main regulator of costamere turnover, was unchanged at 2 weeks but decreased by 27% 16 weeks after surgical release of the infraspinatus tendon. This was accompanied by cleavage of the costamere protein talin into a 190 kDa fragment while full length talin remained unchanged. At 2 weeks after tendon release, muscle volume decreased by 17 cm from an initial 185 cm(3) , the fatty tissue volume was halved, and the contractile tissue volume remained unchanged. After 16 weeks, the muscle volume decreased by 36 cm(3) , contractile tissue was quantitatively lost, and the fat content increased by 184%. Nandrolone administration mitigated the loss of contractile tissue by 26% and prevented fat accumulation, alterations in FAK activity, and talin cleavage. Taken together, these findings imply that muscle remodeling after tendon release occurs in two stages. The early decrease of muscle volume is associated with reduction of fat; while, the second stage is characterized by substantial loss of contractile tissue accompanied by massive fat accumulation. Regulation of costamere turnover is associated with the loss of contractile tissue and seems to be impacted by nandrolone treatment. Clinically, the costamere may represent a potential intervention target to mitigate muscle loss after a rotator cuff tear. © 2017 The Authors. Journal of Orthopaedic Research published by Wiley Periodicals, Inc. on behalf of the Orthopaedic Research Society. J Orthop Res
Band-theoretical prediction of magnetic anisotropy in uranium monochalcogenides
Magnetic anisotropy of uranium monochalcogenides, US, USe and UTe, is studied
by means of fully-relativistic spin-polarized band structure calculations
within the local spin-density approximation. It is found that the size of the
magnetic anisotropy is fairly large (about 10 meV/unit formula), which is
comparable with experiment. This strong anisotropy is discussed in view of a
pseudo-gap formation, of which crucial ingredients are the exchange splitting
of U 5f states and their hybridization with chalcogen p states (f-p
hybridization). An anomalous trend in the anisotropy is found in the series
(US>>USe<UTe) and interpreted in terms of competition between localization of
the U 5f states and the f-p hybridization. It is the spin-orbit interaction on
the chalcogen p states that plays an essential role in enlarging the strength
of the f-p hybridization in UTe, leading to an anomalous systematic trend in
the magnetic anisotropy.Comment: 4 pages, 5 figure
Physical nature of critical wave functions in Fibonacci systems
We report on a new class of critical states in the energy spectrum of general
Fibonacci systems. By introducing a transfer matrix renormalization technique,
we prove that the charge distribution of these states spreads over the whole
system, showing transport properties characteristic of electronic extended
states. Our analytical method is a first step to find out the link between the
spatial structure of these critical wave functions and the quasiperiodic order
of the underlying lattice.Comment: REVTEX 3.0, 11 pages, 2 figures available upon request. To appear in
Phys. Rev. Let
Trace and antitrace maps for aperiodic sequences, their extensions and applications
We study aperiodic systems based on substitution rules by means of a
transfer-matrix approach. In addition to the well-known trace map, we
investigate the so-called `antitrace' map, which is the corresponding map for
the difference of the off-diagonal elements of the 2x2 transfer matrix. The
antitrace maps are obtained for various binary, ternary and quaternary
aperiodic sequences, such as the Fibonacci, Thue-Morse, period-doubling,
Rudin-Shapiro sequences, and certain generalizations. For arbitrary
substitution rules, we show that not only trace maps, but also antitrace maps
exist. The dimension of the our antitrace map is r(r+1)/2, where r denotes the
number of basic letters in the aperiodic sequence. Analogous maps for specific
matrix elements of the transfer matrix can also be constructed, but the maps
for the off-diagonal elements and for the difference of the diagonal elements
coincide with the antitrace map. Thus, from the trace and antitrace map, we can
determine any physical quantity related to the global transfer matrix of the
system. As examples, we employ these dynamical maps to compute the transmission
coefficients for optical multilayers, harmonic chains, and electronic systems.Comment: 13 pages, REVTeX, now also includes applications to electronic
systems, some references adde
Acquisition of multidrug-resistant Enterobacterales during international travel: A systematic review of clinical and microbiological characteristics and meta-analyses of risk factors
Background: International tourism increased from 25 million tourist arrivals in 1950 to over 1.3 billion in 2017. These travelers can be exposed to (multi) resistant microorganisms, may become colonized, and bring them back home. This systematic review aims to identify the carriage rates of multidrug-resistant Enterobacterales (MDR-E) among returning travelers, to identify microbiological methods used, and to identify the leading risk factors for acquiring MDR-E during international travel. Methods: Articles related to our research question were identified through a literature search in multiple databases (until June 18, 2019)-Embase, Medline Ovid, Cochrane, Scopus, Cinahl, Web of Science, and Google Scholar. Results: Out of 3211 potentially relevant articles, we included 22 studies in the systematic review, and 12 studies in 7 random-effects meta-analyses. Highest carriage rates of MDR-E were observed after travel to Southern Asia (median 71%), followed by travel to Northern Africa (median 42%). Carbapenemase-producing Enterobacterales (CPE) were identified in 5 out of 22 studies, from a few patients. However, in only eight out of 22 studies (36.4%) the initial laboratory method targeted detection of the presence of CPE in the original samples. The risk factor with the highest pooled odds ratio (OR) for MDR-E was travel to Southern Asia (pooled OR = 14.16, 95% confidence interval [CI] = 5.50 to 36.45), followed by antibiotic use during travel (pooled OR = 2.78, 95% CI = 1.76 to 4.39). Conclusions: Risk of acquiring MDR-E while travelling increases depending on travel destination and if antibiotics are used during travel. This information is useful for the development of guidelines for healthcare facilities with low MDR-E prevalence rates to prevent admission of carriers without appropriate measures. The impact of such guidelines should be assessed
Highly Conducting pi-Conjugated Molecular Junctions Covalently Bonded to Gold Electrodes
We measure electronic conductance through single conjugated molecules bonded
to Au metal electrodes with direct Au-C covalent bonds using the scanning
tunneling microscope based break-junction technique. We start with molecules
terminated with trimethyltin end groups that cleave off in situ resulting in
formation of a direct covalent sigma bond between the carbon backbone and the
gold metal electrodes. The molecular carbon backbone used in this study consist
of a conjugated pi-system that has one terminal methylene group on each end,
which bonds to the electrodes, achieving large electronic coupling of the
electrodes to the pi-system. The junctions formed with the prototypical example
of 1,4-dimethylenebenzene show a conductance approaching one conductance
quantum (G0 = 2e2/h). Junctions formed with methylene terminated oligophenyls
with two to four phenyl units show a hundred-fold increase in conductance
compared with junctions formed with amine-linked oligophenyls. The conduction
mechanism for these longer oligophenyls is tunneling as they exhibit an
exponential dependence of conductance with oligomer length. In addition,
density functional theory based calculations for the Au-xylylene-Au junction
show near-resonant transmission with a cross-over to tunneling for the longer
oligomers.Comment: Accepted to the Journal of the American Chemical Society as a
Communication
Ein einfaches Verfahren zur Herstellung anellierter Thiophene
A simple method for the synthesis of fused thiophenes by reaction of agr-carboxymethyl substituted cyclic ketones withLawesson-reagent is described. Considerations concerning the reaction mechanism are given
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