Monitoring Changes in Hemodynamics Following Optogenetic Stimulation

The brain is composed of billions of neurons, all of which connected through a vast network. After years of study and applications of different technologies and techniques, there are still more questions than answers when it comes to the fundamental functions of the brain. This project aims to provide a new tool which can be used to gain a better understanding of the fundamental mechanisms that govern neurological processes inside the brain. In order for neural networks to operate, blood has to be supplied through neighboring blood vessels. As such, the increase or decrease in the blood supply has been used as an indicator of neural activity. The neural activity and blood supply relationship is known as neural vasculature coupling. Monitoring the hemodynamics is used as an indicator of neurological activity, but the causal relationship is an area of current research. Gaining a better understanding of the coupling of neural activity and the surrounding vasculature provides a more accurate methodology to evaluate regional neural activity. The new optical technology applied in this project provides a set of tools to both stimulate and monitor this coupling relationship. Optogenetics provides the capability of stimulating neural activity using specific wavelengths of light. Essentially this tool allows for the direct stimulation of networks of neurons by simply shining one color of light onto the brain. Optical Coherence Tomography (OCT), another new optical technology applied in this project, can record volumetric images of blood vessels and flow using only infrared light. The combination of the two optical technologies is then capable of stimulating neural activity and monitoring the hemodynamic response inside the brain using only light. As a result of this project we have successfully demonstrated the capability of both stimulating and imaging the brain using new optical technologies. The optical stimulation of neural activity has evoked a direct hemodynamic effect as anticipated through neural-vasculature coupling. Changes in blood velocity, flow and dilatation were all recorded using the high resolution and high speed capabilities of the OCT system

A Strong-Lensing Model for the WMDF JWST/GTO Very Rich Cluster Abell 1489

We present a first strong-lensing model for the galaxy cluster RM J121218.5+273255.1 ($z=0.35$; hereafter RMJ1212; also known as Abell 1489). This cluster is amongst the top 0.1\% richest clusters in the redMaPPer catalog; it is significantly detected in X-ray and through the Sunyaev-Zel'dovich effect in ROSAT and \emph{Planck} data, respectively; and its optical luminosity distribution implies a very large lens, following mass-to-light scaling relations. Based on these properties it was chosen for the Webb Medium Deep Fields (WMDF) JWST/GTO program. In preparation for this program, RMJ1212 was recently imaged with GMOS on Gemini North and in seven optical and near-infrared bands with the \emph{Hubble Space Telescope}. We use these data to map the inner mass distribution of the cluster, uncovering various sets of multiple images. We also search for high-redshift candidates in the data, as well as for transient sources. We find over a dozen high-redshift ($z\gtrsim6$) candidates based on both photometric redshift and the dropout technique. No prominent ($\gtrsim5 \sigma$) transients were found in the data between the two HST visits. Our lensing analysis reveals a relatively large lens with an effective Einstein radius of $\theta_{E}\simeq32\pm3''$ ($z_{s}=2$), in broad agreement with the scaling-relation expectations. RMJ1212 demonstrates that powerful lensing clusters can be selected in a robust and automated way following the light-traces-mass assumption.Comment: 17 pages, 6 figures, 2 tables; To be submitte

PEARLS: Low Stellar Density Galaxies in the El Gordo Cluster Observed with JWST

A full understanding of how unusually large "Ultra Diffuse Galaxies" (UDGs) fit into our conventional understanding of dwarf galaxies remains elusive, despite the large number of objects identified locally. A natural extension of UDG research is the study of similar galaxies at higher redshift to establish how their properties may evolve over time. However, this has been a challenging task given how severely systematic effects and cosmological surface brightness dimming inhibit our ability to study low-surface brightness galaxies at high-$z$. Here, we present an identification of low stellar surface density galaxies (LDGs), likely the progenitors of local UDGs, at moderate redshift with deep near-IR observations of the El Gordo cluster at $z = 0.87$ with JWST. By stacking 8 NIRCAM filters, we are able to achieve an apparent surface brightness sensitivity of $24.59$ mag arcsec$^{-2}$, faint enough to be complete to the bright end of the LDG population. Our analysis identifies significant differences between this population and local UDGs, such as their color and size distributions, which suggest that UDG progenitors are bluer and more extended at high-$z$ than at $z = 0$. This suggests that multiple mechanisms are responsible for UDG formation and that prolonged transformation of cluster dwarfs is not a primary UDG formation mechanism at high-$z$. Furthermore, we find a slight overabundance of LDGs in El Gordo, and, in contrast to findings in local clusters, our analysis does not show a deficit of LDGs in the center of El Gordo, implying that tidal destruction of LDGs is significant between $z = 0.87$ and $z = 0$.Comment: Resubmitted to ApJ after minor revision

JWST NIRCam Photometry: A Study of Globular Clusters Surrounding Bright Elliptical Galaxy VV 191a at z=0.0513

James Webb Space Telescope NIRCam images have revealed 443 globular cluster (GC) candidates around the $z=0.0513$ elliptical galaxy VV 191a. NIRCam broadband observations are made at 0.9-4.5 $\mu$m using filters F090W, F150W, F356W, and F444W. Using photometry, the data is analyzed to present color-magnitude diagrams (CMDs) that suggest a fairly uniform population of GCs. Color histograms show a unimodal color distribution that is well fit by a single Gaussian, using color to primarily trace the metallicity. The findings show the sample's globular cluster luminosity function (GCLF) does not reach the turnover value and is, therefore, more luminous than what is typically expected, with an absolute AB magnitude, $M_{F090W} = -8.70$ mag, reaching within nearly one magnitude of the classical turnover value. We attribute this to the completeness in the sample. Models show that the mass estimate of the GCs detected tends to be more massive, reaching upward of $\simeq 10^7 M_{\odot}$. However, the results show that current GC models do not quite align with the data. We find that the models appear to be bluer than the JWST data in the reddest (F356W-F444W) filters and redder than the data in the bluest (F090W-F150W) filters and may need to be revised to improve the modeling of near-IR colors of old, metal-poor stellar populations.Comment: 11 pages, 7 figure

PEARLS: Near Infrared Photometry in the JWST North Ecliptic Pole Time Domain Field

We present Near-Infrared (NIR) ground-based Y, J, H, and K imaging obtained in the James Webb Space Telescope North Ecliptic Pole Time Domain Field (TDF) using the MMT-Magellan Infrared Imager and Spectrometer (MMIRS) on the MMT.These new observations cover a field of approximately 230 arcmin^2 in Y, H, and K and 313 arcmin^2 in J. Using Monte Carlo simulations we estimate a 1 sigma depth relative to the background sky of (Y, J, H, K}) = (23.80, 23.53, 23.13, 23.28) in AB magnitudes for point sources at a 95% completeness level. These observations are part of the ground-based effort to characterize this region of the sky, supplementing space-based data obtained with Chandra, NuSTAR, XMM, AstroSat, HST, and JWST. This paper describes the observations and reduction of the NIR imaging and combines these NIR data with archival imaging in the visible, obtained with the Subaru Hyper-Suprime-Cam, to produce a merged catalog of 57,501 sources. The new observations reported here, plus the corresponding multi-wavelength catalog, will provide a baseline for time-domain studies of bright sources in the TDF.Comment: 23 pages, 10 figures. Accepted for publication in ApJS. Images and catalogs available at https://doi.org/10.5281/zenodo.7934393. Data description available under ancillary files and at the Zenodo site. Added a reference, fixed typos in metadat

PEARLS: Near-infrared Photometry in the JWST North Ecliptic Pole Time Domain Field * * Partly based on observations taken with the MMT, a joint facility operated by the University of Arizona and the Smithsonian Institution.

We present near-infrared (NIR) ground-based Y, J, H, and K imaging obtained in the James Webb Space Telescope (JWST) North Ecliptic Pole Time Domain Field (NEP TDF) using the MMT-Magellan Infrared Imager and Spectrometer on the MMT. These new observations cover a field of approximately 230 arcmin2 in Y, H, and K, and 313 arcmin2 in J. Using Monte Carlo simulations, we estimate a 1σ depth relative to the background sky of (Y, J, H, K) = (23.80, 23.53, 23.13, 23.28) in AB magnitudes for point sources at a 95% completeness level. These observations are part of the ground-based effort to characterize this region of the sky, supplementing space-based data obtained with Chandra, NuSTAR, XMM, AstroSat, Hubble Space Telescope, and JWST. This paper describes the observations and reduction of the NIR imaging and combines these NIR data with archival imaging in the visible, obtained with the Subaru Hyper-Suprime-Cam, to produce a merged catalog of 57,501 sources. The new observations reported here, plus the corresponding multiwavelength catalog, will provide a baseline for time-domain studies of bright sources in the NEP TDF

EPOCHS VII: Discovery of high redshift (6.5<z<126.5 < z < 12) AGN candidates in JWST ERO and PEARLS data

We present an analysis of a sample of robust high redshift galaxies selected photometrically from the `blank' fields of the Prime Extragalactic Areas for Reionization Science (PEARLS) survey and Early Release Observations (ERO) data of the James Webb Space Telescope (JWST) with the aim of selecting candidate high redshift active galactic nuclei (AGN). Sources were identified from the parent sample using a threefold selection procedure, which includes spectral energy distribution (SED) fitting to identify sources that are best fitted by AGN SED templates, a further selection based on the relative performance of AGN and non-AGN models, and finally morphological fitting to identify compact sources of emission, resulting in a purity-oriented procedure. Using this procedure, we identify a sample of nine AGN candidates at $6.5 < z < 12$, from which we constrain their physical properties as well as measure a lower bound on the AGN fraction in this redshift range of $5 \pm 1$\%. As this is an extreme lower limit due to our focus on purity and our SEDs being calibrated for unobscured Type 1 AGN, this demonstrates that AGN are perhaps quite common at this early epoch. The rest-frame UV colors of our candidate objects suggest that these systems are potentially candidate obese black hole galaxies (OBG), or AGN with very little galaxy component. We also investigate emission from our sample sources from fields overlapping with Chandra and VLA surveys, allowing us to place X-ray and 3 GHz radio detection limits on our candidates. Of note is a $z = 11.9$ candidate source exhibiting an abrupt morphological shift in the reddest band as compared to the bluer bands, indicating a potential merger or an unusually strong outflow.Comment: Submitted to MNRAS, 12 pages, 11 figures, typos correcte

First Results from The GlueX Experiment

The GlueX experiment at Jefferson Lab ran with its first commissioning beam in late 2014 and the spring of 2015. Data were collected on both plastic and liquid hydrogen targets, and much of the detector has been commissioned. All of the detector systems are now performing at or near design specifications and events are being fully reconstructed, including exclusive production of $\pi^{0}$, $\eta$ and $\omega$ mesons. Linearly-polarized photons were successfully produced through coherent bremsstrahlung and polarization transfer to the $\rho$ has been observed.Comment: 8 pages, 6 figures, Invited contribution to the Hadron 2015 Conference, Newport News VA, September 201