Incidence of ambergris washed ashore

Ambergris is a valuable substance obtained from Sperm whale. It is either found floating in the sea or obtained by cutting open theanimal. It is produced in the intestine and retained mostly in the colon. Ambergris is a solid inflamable waxy substance

Bacillus cereus KLUVAA Mediated Biocement Production Using Hard Water and Urea

In the present study, a potential bacterial strain with maximum urease activity was isolated from urea-rich paddy field soil for biocement production. The bacterial isolate was screened using Christensen selective agar media and named as KLUVAA. This isolate was found to be tolerant up to 10 % urea. 16S rRNA sequencing analysis identified the isolate KLUVAA as Bacillus cereus. Biocement production was carried out using tap water with 431.7 mg L–1 of hardness as a natural source of calcium. Functional groups present in biocement were analysed using FT-IR spectrum. The morphology and elemental composition of the biocement was studied using SEM with EDS mapping and XRD analyses. Thermogravimetric analysis was used to study the thermal stability of the microbial biocement. Further, process parameters were optimized for enhancing the yield of biocement. This work is licensed under a Creative Commons Attribution 4.0 International License

Crafts and gear used for marine fishing along the Andhra Pradesh coast

Until the middle of nineteen sixties fishing for marine finfishes and shellfishes along the Andhra Pradesh coast used to be carried out employing indigenous non-mechanised crafts. Subsequently trawlers and later mechanised vessels operating gillnets came into use which resulted in the increased fish production. Use of outboard engine on indigenous crafts for reaching fishing grounds is a recent feature of near the coast fishing. The different kinds of non-mechanised and mechanised crafts and gear employed in the region are dealt with in this article

Wireless sensor networks for applied research on rain-fed farming in India: an exploratory user experiment

This document describes a user experiment that was conducted between October 2007 and February 2008 around a wireless sensor network for rain-fed agriculture. The experiment was organized jointly by UAS, the CK Trust and the EPFL. The participants came from an Indian university of agriculture, an Indian non-governmental organization active in rain-fed farming sustainability, and the Kanrnataka department of agriculture

Major and minor fisheries harbours of India. 7. The fisheries harbours and fishery along the north Tamilnadu and south Andhra Pradesh coasts

There are four functional fisheries harbours in the north Tamil Nadu-south Andhra Pradesh coast, viz., Chennai (major), Nizampatnam, Cuddalore and Pazhayar (minor). A medium harbour in Pondicherry is under construction. There is a temporary jetty in Krishnapatnam and a fish landing platform in Pulicat

STABILITY INDICATING RP-HPLC METHOD FOR THE ESTIMATION OF QUETIAPINE FUMARATE IN BULK AS WELL AS IN PHARMACEUTICAL DOSAGE FORM

This study was designed to develop and validate a simple, sensitive, precise, and specific stability indicating reverse phase high-performance liquid chromatographic (HPLC) method for estimation of Quetiapine Fumarate in bulk and its tablet dosage form. The HPLC separation was carried out by reverse phase chromatography on Thermo column Symmetry C18 (4.6 x 150mm, 5 mm) with a mobile phase composed Sodium dihydrogen phosphate and the pH was adjusted to 4.0 by Orthophosporic Acid & Methanol in the ratio of 35:65 v/v in isocratic mode at a flow rate of 1.0 ml/min. The run time was maintained for 6mins. The detection was monitored at 290 nm. The calibration curve for Quetiapine Fumarate was linear from 20 to60 µg/ml. The inter-day and intra-day precision was found to be within the limits. The proposed method was adequate sensitivity, reproducibility, and specificity for the determination of Quetiapine Fumarate in bulk and its tablet dosage forms. The limit of detection [LOD] and limit of quantification [LOQ] for Quetiapine Fumarate were found to be 0.01 µg/ml and 0.03 µg /ml respectively. The Accuracy recoveries were 100.0-100.4% and reproducibility was found to be satisfactory. The bulk active pharmaceutical ingredient was subjected to  thermal,  photolytic,  hydrolytic  (acidic  and  basic)  and  oxidative  stress  conditions  and  stressed  samples  were analyzed by the proposed method. The method was validated in terms of linearity, precision, accuracy, specificity and robustness. All the validation was done as per ICH guidelines. The proposed method was simple, fast, accurate, and precise for the quantification of Quetiapine Fumarate in the dosage form, bulk drugs as well as for routine analysis in quality control. Key-Words: Quetiapine Fumarate, RP-HPLC, ICH, Stability Indicating Studies, LOD, LOQ

Current Treatment and Outcomes Benchmark for Locally Advanced or Metastatic Urothelial Cancer From a Large UK-Based Single Centre

Objectives: To characterize treatment patterns and survival outcomes for patients with locally advanced or metastatic malignancy of the urothelial tract during a period immediately preceding the widespread use of immune checkpoint inhibitors in the UK. Patients and Methods: We retrospectively examined the electronic case notes of patients attending the Leeds Cancer Center, UK with locally advanced or metastatic urothelial carcinoma, receiving chemotherapy between January 2003 and March 2017. Patient characteristics, treatment patterns, and outcomes were collected. Summary and descriptive statistics were calculated for categorical and continuous variables as appropriate. The Kaplan–Meier method was used to estimate median survival and Cox regression proportional hazards model was used to explore relationships between clinical variables and outcome. Results: Two hundred and sixteen patients made up the study cohort, with a median age of 66 years (range: 35–83) and 72.7% being male. First-line treatment consisted of either a cisplatin- (44%) or carboplatin-based regimen (48%) in the majority of patients. Twenty seven percent of patients received a second-line of treatment (most commonly single-agent paclitaxel) following a first-line platinum containing regimen. Grade 4 neutropenia was observed in 19 and 27% of those treated with a first-line cisplatin- and carboplatin-based regimen, respectively. The median overall survival (mOS) of the study cohort was estimated to be 16.2 months (IQR: 10.6–28.3 months). Receipt by patients of cisplatin-based chemotherapy was associated with a longer mOS and this association persisted when survival analysis was adjusted for age, sex, performance status and presence of distant metastases. Conclusions: This study provides a useful benchmark for outcomes achieved in a real-world setting for patients with locally advanced or metastatic UC treated with chemotherapy in the immediate pre-immunotherapy era

Major and minor fisheries harbours of India. 8. Fisherries harbours along the coasts of North Andhra Pradesh, Orissa and West Bengal

The present account gives information about the three major and five minor fisheries harbours along the coasts of north Andhra Pradesh, Orissa and West Benga