Dermatoscopia da doença de Bowen: variante pigmentada no pênis

Pigmented Bowen's disease (PBD) is a variant of squamous cell carcinoma in situ and represents less than 2% of cases of Bowen's disease. It is characterized by a sharply demarcated, pigmented plaque with a scaly or crusted surface on intertriginous and genital areas. The authors describe a case of PBD on the penis and analyze the dermoscopic aspects of this type of lesion.A doença de Bowen Pigmentada (DBP) é uma variante do carcinoma espinocelular in situ e compreende menos de 2% dos casos da Doença de Bowen. Apresenta-se como placa pigmentada, hiperqueratósica, delimitada, localizada em áreas intertriginosas e anogenital. Os autores descrevem um caso de DBP no pênis e abordam os aspectos dermatoscópicos dessa lesão.Federal University of São Paulo Department of DermatologyFederal University of São Paulo Department of PathologyUNIFESP, Department of DermatologyUNIFESP, Department of PathologySciEL

Case report: dermoscopic and histological aspects of skin graft and perigraft hyperpigmentation in acral location

Little is known about the use of dermoscopy in skin grafting. We describe the case of a patient with skin grafting and surrounding pigmentation on acral region. The dermoscopic findings were similar to those of benign acral lesions (lattice-like pattern) and reactive pigmentations (fine striae). Histopathology revealed pigment leakage and increased number of melanocytes. It is believed that this phenomenon occured as the result of an inflammatory stimulus.Universidade Estadual de LondrinaUniversidade Federal de São Paulo (UNIFESP)aff03UNIFESPSciEL

Dermoscopy in nail psoriasis

The authors report on their experience with the use of dermoscopy in nail psoriasis and describe their findings with this diagnostic tool.Os autores relatam sua experiência no uso da dermatoscopia na psoríase ungueal e descrevem os achados dessa ferramenta diagnóstica.Santa Casa de São Paulo Clínica de dermatologiaUniversidade de BolonhaHospital do Servidor Público do Estado de São Paulo Clínica de dermatologiaUniversidade Federal de São Paulo (UNIFESP) departamento de dermatologiaUNIFESP, Depto. de dermatologiaSciEL

Prevalência de lesões pré-neoplásicas e tumores cutâneos não melanomas em nipo-brasileiros residentes na cidade de Bauru, São Paulo, Brasil

Precancerous lesions and skin cancer are infrequent in Asians, and have received little documentation in the literature. Brazil has the world's largest contingent of Japanese immigrants and their descendants, and 70% live in the State of São Paulo. The prevalence of such skin lesions in Japanese-Brazilians is unknown. This study aimed to assess the prevalence of actinic keratoses and non-melanoma skin cancer in first and second-generation Japanese-Brazilians over 30 years of age, without miscegenation, living in the city of Bauru, São Paulo State, in 2006. Of the 567 Japanese-Brazilians that underwent dermatological examination, actinic keratosis was diagnosed in 76, with a mean age of 68.9 years, and a single case of basal cell carcinoma was detected in a 39-year-old female patient. In Japan, prevalence of actinic keratosis varies from 0.76% to 5%, and the incidence of non-melanoma skin cancer is 1.2 to 5.4/100 thousand. Japanese-Brazilians from Bauru showed a 13.4% prevalence of actinic keratoses and earlier age at onset. Proximity to the Equator and a history of farming contribute to these higher rates. Presence of solar melanosis was associated with a 1.9-fold risk of developing actinic keratosis.Manifestações cutâneas pré-neoplásicas e neoplásicas em asiáticos são infreqüentes e pouco documentadas. O Brasil possui o maior contingente de imigrantes japoneses e 70% deles residem no Estado de São Paulo. A prevalência dessas lesões em nipo-brasileiros é desconhecida. O presente estudo tem como objetivo avaliar a prevalência de queratoses actínicas e tumores cutâneos não melanomas em nipo-brasileiros acima de trinta anos de 1ª geração ou 2ª geração, sem miscigenação, residentes na cidade de Bauru, no ano de 2006. Dos 567 nipo-brasileiros submetidos a exame dermatológico, diagnosticou-se queratose actínica em 76 pacientes, com média de idade de 68,9 anos, e único carcinoma basocelular em paciente do sexo feminino de 39 anos. No Japão, a prevalência de queratose actínica é de 0,76% a 5% e a incidência de tumores cutâneos não melanomas é de 1,2 a 5,4/100 mil. Os nipo-brasileiros de Bauru apresentaram prevalência de 13,4% de queratoses actínicas e idade mais precoce de aparecimento. Proximidade com o Equador e atividades rurais contribuem para esses achados. A presença de melanose solar demonstrou risco 1,9 vez maior de desenvolver queratose actínica.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Estadual Paulista Faculdade de Medicina de BotucatuUNIFESP, EPMSciEL

Dysplastic nevus associated with seborrheic keratosis

Seborrheic keratosis is a common skin lesion which may coincidentally be associated melanocytic nevi. The authors describe a case of dysplastic nevus associated with seborrheic keratosis and discuss the clinical, dermoscopic, and histological findings of this association. They also discuss the association between seborrheic keratosis and other benign and malignant tumours.Federal University of São Paulo Department of DermatologyFederal University of São Paulo Department of PathologyFederal University of São Paulo Departments of Dermatology and PathologyFederal University of São Paulo Departments of DermatologyUNIFESP, Department of DermatologyUNIFESP, Department of PathologyUNIFESP, Departments of Dermatology and PathologyUNIFESP, Departments of DermatologySciEL

Necrobiotic xanthogranuloma without paraproteinemia

Necrobiotic xanthogranuloma is a chronic granulomatous and xantomathous disease, characterized by indurated, nontender, yellowish and erythematous nodules and plaques especially located on the periorbital region. It is commonly associated with paraproteinemia and an increased risk for hematological and lymphoproliferative malignancies. Its pathogenesis remains unclear. Alkylating agents, such as chlorambucil and melphalan may be used to treat the disease with variable success. We report a case of this rare disease in a patient with a solitary tumor and without paraproteinemia.O xantogranuloma necrobiótico é doença crônica granulomatosa e xantomatosa, caracterizada por pápulas e placas infiltradas, eritematosas e amareladas, preferencialmente localizadas na região periorbital. É comum associar-se com paraproteinemia e risco aumentado para malignidades hematológicas e linfoproliferativas. Sua patogênese permanece desconhecida. Agentes alquilantes, como clorambucil e melfalan, podem ser utilizados no tratamento com sucesso variável. Relata-se um exemplo dessa rara doença em paciente com lesão única e sem paraproteinemia.Universidade Federal de São Paulo (UNIFESP) Departamento de Dermatologia Escola Paulista de MedicinaUNIFESP, Depto. de Dermatologia Escola Paulista de MedicinaSciEL

Original Method to Repigment Achromic Laser Tattoo Removal Scars

Laser tattoo removal is expensive, painful, and time-consuming. Even with the use of the right laser equipment, it is often impossible to eliminate all pigments. Incomplete tattoo removal, one of the undesired effects of laser treatment, is widely disseminated in the media and accepted by most patients. However, few patients know that laser tattoo removal can cause permanent scars. Some patients who develop achromic scars can feel disappointed with the results of laser tattoo removal and take legal action against the physician responsible for the treatment. This paper describes our experience with a drug delivery treatment called MMP® (“Microinfusão de Medicamentos na Pele,” Portuguese acronym for “Microinfusion of Drugs in the Skin”) that repigments and improves the final esthetic results of achromic laser tattoo removal scars

A case of pigmented Bowen's disease

Pigmented Bowen's disease is a rare subtype of Bowen's disease. Clinically it presents as a slow-growing, well-defined, hyperpigmented plaque, and should be included as a differential diagnosis of other pigmented lesions. The authors describe a challenging case of pigmented Bowen's disease with non-diagnostic dermscopy findings.Fed Univ Sao Paulo Unifesp, Dept Dermatol, Sao Paulo, SP, BrazilDermatology Department of the Universidade Federal de São Paulo (UNIFESP) - São Paulo (SP), BrazilPathology Department of the Universidade Federal de São Paulo (UNIFESP) - São Paulo (SP), BrazilWeb of Scienc

Polypoid melanoma and superficial spreading melanoma different subtypes in the same lesion

Melanoma is a malignant melanocytic neoplasm with high mortality rate, and steadily and universally increasing incidence rates. Polypoid melanoma is considered an exophytic variant of the nodular subtype. The incidence of polypoid melanoma is extremely variable, most likely because of the different criteria used for its characterization. We presented a rare case of polypoid melanoma and superficial spreading melanoma in the same lesion.Universidade Federal de São Paulo (UNIFESP)UNIFESPSciEL

Melanoma developed during pregnancy - A case report

We describe a case of plantar interdigital cutaneous melanoma in a 22-year-old woman who reported changes in a pigmented lesion during pregnancy. Diagnosis was late and evolution unfavourable. The purpose of this report is to draw the attention of dermatologists to the need for careful regular examination of melanocytic lesions in pregnant women, not ignoring possible changes as always physiological.Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Department of DermatologyUniversidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Departments of Dermatology and PathologyUNIFESP, EPM, Department of DermatologyUNIFESP, EPM, Departments of Dermatology and PathologySciEL