Monte Carlo calculations on the gauge Potts model

The q-state gauge Potts model Pq in d-dimensions has been studied using Monte Carlo techniques. For d=2 no phase transitions were detected. The P2 model for d=3 shows a second order phase transition. On the other hand, all the d=3 (q≠2) and d=4 cases studied show first order phase transitions. In these cases, it was possible to estimate transition coupling parameters as well as latent heat. For selected cases, a study of the behavior of the Wilson loop factor was done.Facultad de Ciencias Exacta

Influence of the LPM effect and dielectric suppression on particle air showers

An analysis of the influence of the Landau-Migdal-Pomeranchuk (LPM) effect on the development of air showers initiated by astroparticles is presented. The theory of Migdal is studied and compared with other theoretical methods, particularly the Blankenbecler-Drell approach. By means of realistic computer simulations and using algorithms that emulate Migdal's theory, including also the so-called dielectric suppression, we study the behavior of the relevant observables in the case of ultrahigh energy primaries. We find that the LPM effect can significantly modify the development of high energy electromagnetic showers in certain cases.Facultad de Ciencias Exacta

Incorporation of QCD Effects in Basic Corrections of the Electroweak Theory

We study the incorporation of QCD effects in the basic electroweak corrections \drcar, \drcarw, and \dr. They include perturbative \Ord{\alpha\alpha_s} contributions and $t\bar{t}$ threshold effects. The latter are studied in the resonance and Green-function approaches, in the framework of dispersion relations that automatically satisfy relevant Ward identities. Refinements in the treatment of the electroweak corrections, in both the \ms\ and the on-shell schemes of renormalization, are introduced, including the decoupling of the top quark in certain amplitudes, its effect on \hat{e}^2(\mz) and \sincarmz, the incorporation of recent results on the leading irreducible \Ord{\alpha^2} corrections, and simple expressions for the residual, i.e.\ ``non-electromagnetic'', parts of \drcar, \drcarw, and \dr. The results are used to obtain accurate values for \mw\ and \sincarmz, as functions of \mt\ and \mh. The higher-order effects induce shifts in these parameters comparable to the expected experimental accuracy, and they increase the prediction for \mt\ derived from current measurements. The \ms\ and the on-shell calculations of \dr, in a recently proposed formulation, are compared and found to be in excellent agreement over the wide ranges 60\GeV \leq \mh \leq 1 \TeV, \mz \leq \mt \leq 250 \GeV.Comment: 51 pages (needs doublespace, equations, and cite styles

The Two Caenorhabditis elegans UDP-Glucose:Glycoprotein Glucosyltransferase Homologues Have Distinct Biological Functions

The UDP-Glc:glycoprotein glucosyltransferase (UGGT) is the sensor of glycoprotein conformations in the glycoprotein folding quality control as it exclusively glucosylates glycoproteins not displaying their native conformations. Monoglucosylated glycoproteins thus formed may interact with the lectin-chaperones calnexin (CNX) and calreticulin (CRT). This interaction prevents premature exit of folding intermediates to the Golgi and enhances folding efficiency. Bioinformatic analysis showed that in C. elegans there are two open reading frames (F48E3.3 and F26H9.8 to be referred as uggt-1 and uggt-2, respectively) coding for UGGT homologues. Expression of both genes in Schizosaccharomyces pombe mutants devoid of UGGT activity showed that uggt-1 codes for an active UGGT protein (CeUGGT-1). On the other hand, uggt-2 coded for a protein (CeUGGT-2) apparently not displaying a canonical UGGT activity. This protein was essential for viability, although cnx/crt null worms were viable. We constructed transgenic worms carrying the uggt-1 promoter linked to the green fluorescent protein (GFP) coding sequence and found that CeUGGT-1 is expressed in cells of the nervous system. uggt-1 is upregulated under ER stress through the ire-1 arm of the unfolded protein response (UPR). Real-time PCR analysis showed that both uggt-1 and uggt-2 genes are expressed during the entire C. elegans life cycle. RNAi-mediated depletion of CeUGGT-1 but not of CeUGGT-2 resulted in a reduced lifespan and that of CeUGGT-1 and CeUGGT-2 in a developmental delay. We found that both CeUGGT1 and CeUGGT2 play a protective role under ER stress conditions, since 10 µg/ml tunicamycin arrested development at the L2/L3 stage of both uggt-1(RNAi) and uggt-2(RNAi) but not of control worms. Furthermore, we found that the role of CeUGGT-2 but not CeUGGT-1 is significant in relieving low ER stress levels in the absence of the ire-1 unfolding protein response signaling pathway. Our results indicate that both C. elegans UGGT homologues have distinct biological functions