346 research outputs found

    A study on the cooperative plan of water resources field between South Korea and North Korea

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    Thesis(Master) --KDI School:Master of Public Management,2018.This research paper aims to prepare a cooperation plan in water resources field between South and North Korea. In other words, this study has a meaning as a policy preparation phase to make a cooperative plan of water resources field in advance. Through this research paper, I assessed the current status of water resources in North Korea. Then, I would try to identify the problems of North Korea’s water resources field through the literature review, document analysis, and strategic analysis by using tools. In addition, I investigated cases of cooperation not only domestic cases in Korea but also foreign countries cases. Eventually, the most important thing in this research is that this paper suggests a cooperative plan of water resources field based on the questionnaire survey and its analysis. The questionnaire survey would conduct an actual survey to apply the judgment sampling method for the expert group and the general public group. Finally, the purpose of this study is not to concentrate on the short-term perspective of water resources cooperation. Instead, the research is primarily focused on suggesting mechanisms for water resources cooperation in the long-term perspective that can sustainably alleviate the disparity in water resources between the two countries.1. Introduction 2. Literature review 3. Document analysis and case studies 4. Questionnaire survey 5. ConclusionmasterpublishedSeongwon, JIN

    COVID-19: Lessons from South Korean Pandemic Communications Strategy

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    There is a pressing need for evidence on effective COVID-19 pandemic mitigation efforts. The impact of the pandemic has been far-reaching, making management of the outbreak a daunting task for many countries. As the whole world continues to fight against the pandemic, a close examination of best practices of pandemic management is ever timely. Based on social marketing concepts, this paper reviews the system-level communication strategies used in South Korea in response to the COVID-19 pandemic. South Korea has received growing recognition for its response to the COVID-19 pandemic and provides a noteworthy example of positive and effective pandemic communication. Applying a social marketing mix framework, the paper examines South Korean pandemic communication strategies and identified a high degree of transparency and coherence two major success factors. This paper contributes to the current and future healthcare management literature and practice by delineating factors underscoring successful public health crisis management

    Performance assessment of urban precinct design: a scoping study

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    Executive Summary: Significant advances have been made over the past decade in the development of scientifically and industry accepted tools for the performance assessment of buildings in terms of energy, carbon, water, indoor environment quality etc. For resilient, sustainable low carbon urban development to be realised in the 21st century, however, will require several radical transitions in design performance beyond the scale of individual buildings. One of these involves the creation and application of leading edge tools (not widely available to built environment professions and practitioners) capable of being applied to an assessment of performance across all stages of development at a precinct scale (neighbourhood, community and district) in either greenfield, brownfield or greyfield settings. A core aspect here is the development of a new way of modelling precincts, referred to as Precinct Information Modelling (PIM) that provides for transparent sharing and linking of precinct object information across the development life cycle together with consistent, accurate and reliable access to reference data, including that associated with the urban context of the precinct. Neighbourhoods are the ‘building blocks’ of our cities and represent the scale at which urban design needs to make its contribution to city performance: as productive, liveable, environmentally sustainable and socially inclusive places (COAG 2009). Neighbourhood design constitutes a major area for innovation as part of an urban design protocol established by the federal government (Department of Infrastructure and Transport 2011, see Figure 1). The ability to efficiently and effectively assess urban design performance at a neighbourhood level is in its infancy. This study was undertaken by Swinburne University of Technology, University of New South Wales, CSIRO and buildingSMART Australasia on behalf of the CRC for Low Carbon Living

    Bank Consolidation and its Effect on Service Quality

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    The perceived quality of customer service plays a significant role in high involvement products and services. Previous research in the area of bank service quality suggests that as a bank is acquired the quality of service at the new larger bank does not equal what customers received at their old smaller bank. In addition, a newly consolidated bank may eliminate tailored services and create customer dissatisfaction due to higher fees, lower levels of service, and credit availability. Although prior research has focused on specific aspects of bank services, a contribution to the literature can be made by examining this topic in the context of broader dimensions of customer service. Therefore the objective of this research is to determine 1) if overall customer service differs between small bank and large bank organizations and 2) if service quality dimensions of tangibles, reliability, responsiveness, assurance, and empathy differ between small and large bank organizations

    Characterization of Phosphorylated Tau-Microtubule complex with Molecular Dynamics (MD) simulation

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    Alzheimer's Disease (AD), a neurodegenerative disorder, is reported as one of the most severe health and socioeconomic problems in current public health. Tau proteins are assumed to be a crucial driving factor of AD that detach from microtubules (MT) and accumulate as neurotoxic aggregates in the brains of AD patients. Extensive experimental and computational research has observed that phosphorylation at specific tau residues enhances aggregation, but the exact mechanisms underlying this phenomenon remain unclear. In this study, we employed molecular dynamics (MD) simulations on pseudo-phosphorylated tau-MT complex (residue 199 ~ 312), incorporating structural data from recent cryo-electron microscopy studies. Simulation results have revealed altered tau conformations after applying pseudo-phosphorylation. Additionally, root-mean-square deviation (RMSD) analyses and dimensionality reduction of dihedral angles revealed key residues responsible for these conformational shiftsComment: 27pages, 12 figur

    PeptideBERT: A Language Model based on Transformers for Peptide Property Prediction

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    Recent advances in Language Models have enabled the protein modeling community with a powerful tool since protein sequences can be represented as text. Specifically, by taking advantage of Transformers, sequence-to-property prediction will be amenable without the need for explicit structural data. In this work, inspired by recent progress in Large Language Models (LLMs), we introduce PeptideBERT, a protein language model for predicting three key properties of peptides (hemolysis, solubility, and non-fouling). The PeptideBert utilizes the ProtBERT pretrained transformer model with 12 attention heads and 12 hidden layers. We then finetuned the pretrained model for the three downstream tasks. Our model has achieved state of the art (SOTA) for predicting Hemolysis, which is a task for determining peptide's potential to induce red blood cell lysis. Our PeptideBert non-fouling model also achieved remarkable accuracy in predicting peptide's capacity to resist non-specific interactions. This model, trained predominantly on shorter sequences, benefits from the dataset where negative examples are largely associated with insoluble peptides. Codes, models, and data used in this study are freely available at: https://github.com/ChakradharG/PeptideBERTComment: 24 page

    EFFECTS OF CALF ANCHORING COMPRESSION LEVELS ON ANKLE KINEMATICS, MOTOR UNIT BEHAVIOR, ENERGY COST, AND DISCOMFORT DURING WALKING

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    We propose a method for quantifying the anchoring compression of wearable devices using limb occlusion pressure (LOP). Under 0%, 20%, 40%, and 60% of LOP, five healthy male participants performed an isometric ankle plantarflexion task before and after walking on an inclined treadmill. Significant differences were shown in calf discomfort (p \u3c 0.001), and ankle plantarflexion angle (p = 0.013) during walking. Although no significant difference was found for oxygen consumption and motor unit behavior of the gastrocnemius medialis, the maintenance of ankle plantarflexion angle was related to an increase in peak motor unit action potential amplitude and average firing rate at 60% of LOP. The results suggest that subjective assessment is more sensitive than the physiological indices, and calf anchoring force should not exceed 60% LOP to avoid any possible negative effect on the muscle
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