An Artificial Intelligence Application in Health Developed on Covid-19 Documents

With the developments in computer science, the concept of artificial intelligence has appeared more frequently in recent years. The concept of artificial intelligence, which is basically defined as computers (machines) thinking like people and making decisions, has become very popular today. Artificial intelligence is used in many fields, especially computer science, education, law, trade, tourism and economy. The health sector is one of these areas. The importance of the applications developed in health sciences has emerged once again, especially during the pandemic process. The development of systems that help reduce the workload of healthcare professionals and make decisions by processing medical data is also an important and real problem that can be solved with artificial intelligence. In this study, natural language processing which is one of the main study subjects of artificial intelligence, has been developed a system that automatically determines the concepts such as disease, medication and treatment on medical data with artificial intelligence by the system. During the experimental studies, it was observed that 91% accurate estimation was made with the model developed. For this study, a Turkish dataset was created by scanning medical articles and studies related to Covid-19 disease.Keywords: Artificial Intelligence, Turkish natural language processing, Name entity recognition, Covid-19DOI: 10.7176/JHMN/75-0

Double cantilever indirect tension testing for fracture of quasibrittle materials

The Double Cantilever Beam (DCB) Mode I fracture testing has been widely used in fracture testing of especially fiber reinforced polymer composites and adhesive joints. Application of classical DCB testing to plain concrete or unreinforced ceramic specimens is not straightforward and cannot be carried out as in fiber reinforced polymer composites. Instead, an indirect tension approach is proposed in this study. Tests of notched geometrically similar DCB specimens made of normal and high strength concretes loaded eccentrically at the cantilever beam-column ends in compression have been carried out. Classical Type II size effect analyses of peak loads obtained from these tests are performed. The Microplane Model M7 is calibrated independently using uniaxial compression tests and employed to predict the peak loads of both tested and virtual geometrically similar DCB specimens. The same size effect analyses are performed on the predicted peak loads and the errors in the fracture parameters of the classical size effect analysis are determined.Peer ReviewedPostprint (author's final draft

Feeding a Protective Hydrolysed Casein Diet to Young Diabetes-prone BB Rats Affects Oxidation of L[U−C14] glutamine in Islets and Peyer's Patches, Reduces Abnormally High Mitotic Activity in Mesenteric Lymph Nodes, Enhances Islet Insulin and Tends to Normalize NO Production

The present studies were undertaken to examine concomitant diet-induced changes in pancreatic islets and cells of the gut immune system of diabetes-prone BB rats in the period before classic insulitis. Diabetes-prone (BBdp) and control non-diabetes prone (BBc) BB rats were fed for ~ 17 days either a mainly plant-based standard laboratory rodent diet associated with high diabetes frequency, NIH-07 (NIH) or a protective semipurified diet with hydrolyzed casein (HC) as the amino acid source. By about 7 weeks of age, NIH-fed BBdp rats had lower plasma insulin and insulin/glucose ratio, lower insulin content of isolated islets, lower basal levels of NO but higher responsiveness of NO production to IL-1β in cultured islets, and higher Con A response and biosynthetic activities in mesenteric lymphocytes than control rats fed the same diet. In control rats, the HC diet caused only minor changes in most variables, except for a decrease in oxidation of L-[U−C14]glutamine in Peyer's patch (PP) cells and an increase in protein biosynthesis in mesenteric lymphocytes. In BBdp rats, however, the HC diet increased plasma insulin concentration, islet insulin/ protein ratio, and tended to normalize the basal and IL-1β-stimulated NO production by cultured islets. The HC diet decreased oxidation of L-[U−C14]glutamine in BBdp pancreatic islets, whereas oxidation of L-[U−C14]glutamine in PP cells was increased, and the basal [Methyl-H3] thymidine incorporation in mesenteric lymphocytes was decreased. These findings are compatible with the view that alteration of nutrient catabolism in islet cells as well as key cells of the gut immune system, particularly changes in mitotic and biosynthetic activities in mesenteric lymphocytes, as well as basal and IL-1β stimulated NO production, participate in the sequence of events leading to autoimmune diabetes in BB rats. Thus, the protection afforded by feeding a hydrolysed casein-based diet derives from alterations in both the target islet tissue and key cells of the gut immune system in this animal model of type 1 diabetes

Contribution à l'étude du métabolisme glucidique dans les îlots de Langerhans

Doctorat en Sciencesinfo:eu-repo/semantics/nonPublishe

The stimulus-secretion coupling of glucose-induced insulin release. XXXIX. Long term effects of K+ deprivation upon insulin biosynthesis and release

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

The coupling of metabolic to secretory events in pancreatic islets: comparison between insulin release and cytosolic redox state.

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Glucokinase is not the pancreatic B-cell glucoreceptor

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Mitochondrial oxidative events and Pasteur or Crabtree effects in pancreatic islet cells

info:eu-repo/semantics/publishe