Preoperative MELD-Na Score Predicts 30-day Post-operative Complications After Colorectal Resection for Malignancy

Introduction:Predicting possible complications in colon surgery is important in terms of reducing postoperative mortality and morbidity rates. Various scoring methods have been used to predict these complications. The MELD score was developed to predict mortality following Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement in cirrhotic patients. This model was revised by adding Na data and used to predict complications in non-cirrhotic patients. We investigated the value of the MELD-Na score in predicting postoperative 30-day complications in patients undergoing colorectal resection for malignancy.Methods:Patients who underwent colorectal resection for malignant diseases were included in the study. Demographics and clinical outcomes were recorded. The MELD-Na scores of the patients were calculated within 48 h before the surgery. Patients were divided into 2 groups according to the status of development of any complication.Results:Age, gender, operative time, and length of stay was not statistically significant for developing complications. The MELD-Na score was significantly higher in patients with any complications. Also, MELD-NA score, stoma creation, and postoperative erythrocyte suspension replacement were found to be independent risk factors for developing complications in patients undergoing surgery for colon cancer.Conclusion:The MELD-Na score may predict the complications that may develop in the first 30 days postoperatively in patients undergoing colorectal resection for malignant diseases

Örgü sabiti uyuşmayan tek cins atomlu heteroyapıların elektronik özelliklerinin yoğunluk fonksiyonel teorisi ile incelenmesi

Bu çalışmada (001) yönünde tekli ve ikişer katmanlı olarak modellenmiş Si/Ge bulk heteroyapının taban durumdaki örgü sabiti, toplam enerjisi ve ortalama efektif potansiyeli yoğunluk fonksiyonel teorisi ile incelenmiştir. Hesaplamalar, temeli Yoğunluk Fonksiyonel Teorisi’ne dayanan Düzlem Dalga Öz Uyum Alan Programı kullanılarak yapılmıştır. Hesaplamaların sonucunda Si ve Ge’un efektif potansiyelleri arasında belirgin bir fark olduğu görülmüştür. Bu sonuç Si ve Ge gibi malzemelerin kuantum kuyularının üretilmesinde kullanılmasını sağlar. Bundan dolayı, bu sistem elektronik ve opto-elektronik aletlerin yapımında önemli bir role sahiptir.In this study, at the ground state, lattice constant, total energy and average effective potential of Si/Ge bulk heterostructure which are modeled as monolayer and bilayer in the (001) direction have been investigated by using Density Functional Theory. The calculations have been done by using Plane Wave Self Consistent Field Program based on Density Functional Theory. An obvious different between effective potentials of Si and Ge has observed in the result of calculations. It has provided to use in make of quantum wells of materials such as Si and Ge. Therefore, it has an important role in invent of electronic and opto-electronic devices

Theoretical investigation of structural and electronic properties of doped semiconductor nanowires

Bu tezde, Zinc blende yapıdaki BN yarıiletkeninin bulk ve (001) yönü boyunca uzanan farklı çaplardaki nanotellerinin yapısal ve elektronik özellikleri Yoğunluk Fonksiyonel Teorisi’ne dayanan Düzlem Dalga Öz Uyum Alan (PWSCF) programı kullanılarak incelenmiştir. BN yarıiletkeninden oluşturulan 0.72 nm, 0.92 nm ve 1.45 nm olmak üzere üç farklı çapta modellenen nanotellerin merkez atomu yerine Cr ve Mn atomları katkılanarak elektronik özellikleri araştırılmıştır. Cr ve Mn katkısının, nanotellerin bant aralığının daralmasına ve iletkenliğin artmasına neden olduğu belirlenmiştir. Spin polarize durumlar incelendiğinde 0.92 nm çaplı Cr katkılı BN nanotelinin toplam durum yoğunluğunun spin yukarı ve spin aşağı durumları simetrik bir yapı göstermektedir. Bununla beraber, diğer tüm nanotellerin toplam durum yoğunluklarından antisimetrik yapı elde edilmiştir.abstractIn this thesis, structural and electronic properties of bulk structure of BN semiconductor in Zinc blende and nanowires with different diameter in the (001) direction have been examined by using Plane Wave Self Consistent Field (PWSCF) based on Density Functional Theory. The electronic properties of BN semiconductor nanowires with different diameter 0.72 nm, 0.92 nm and 1.45 nm have been investigated by substitutioning centre atom of these nanowires with either Cr or Mn atoms. Substitution of Cr and Mn, the nanowires is determined that the band gap narrowing and cause increased conductivity. In the analysis of spin polarized states, it is observed that in 0.92 nm diameter Cr doped BN nanowire, spin up and spin down states show symmetric structure. However, for all other nanowires antisymmetric structure has been obtained from the total density of states

Türkiye'de 1984-1998 yılları arasında özelleştirme politikası ve uygulamaları

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2014.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Yeni, Harun

Tarabya Sahili'nin değişmeyen yüzü : Büyük Tarabya Otel

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2018.This work is a student project of the Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.The History of Turkey course (HIST200) is a requirement for all Bilkent undergraduates. It is designed to encourage students to work in groups on projects concerning any topic of their choice that relates to the history of Turkey. It is designed as an interactive course with an emphasis on research and the objective of investigating events, chronologically short historical periods, as well as historic representations. Students from all departments prepare and present final projects for examination by a committee, with 10 projects chosen to receive awards.Includes bibliographical references (pages 16-17).by Abdürrahim Özer

Lacosamide-Induced Visual Hallucinations and Psychosis: a Case Report and Literature Review

Lacosamide (LCM) has both frequent side effects, such as headache, diplopia, and nausea, and rare side effects such as depression, mood changes, and confusion. This article presents a case of possible LCM-induced psychosis and reviews the literature. A 22-year-old woman presented to the Emergency Department in Status Epilepticus. The seizure was treated with intravenous midazolam and valproic acid. However, she developed cardiopulmonary arrest and was resuscitated successfully. She was intubated and admitted to the intensive care unit. She had first been diagnosed with epilepsy 15 years earlier and had been seizure-free for 3 years. She had undergone a sleeve gastrectomy 1 year earlier. She was extubated the day after admission. LCM 200 mg/day was added to the treatment because of generalized seizures beginning in the right arm. Her seizures were controlled on the 4th hospital day. However, after starting LCM, she developed agitation, visual hallucinations with a sexual content, and intellectual delusions. Therefore, the LCM was discontinued and her psychosis resolved completely 4 days later. On the 12th hospital day, she was discharged. LCM blocks sodium channels and can act as a mood stabilizer and sedative. However, our patient developed psychosis with LCM treatment. This is the first reported case of LCM-induced psychosis in Turkey. Visual hallucinations and psychosis may develop immediately after starting LCM therapy. Clinical recovery can be achieved by discontinuing the drug

Türkiye’ye Bowling'in gelişi ve gelişimi

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2015.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Özer, Abdürrahim

Clinical, Electrophysiological, Radiological Features and Prognosis of Creutzfeldt – Jakob Disease

Objectives:Creutzfeldt- Jakob Disease (CJD) is a neurodegenerative disease characterized by abnormally-shaped proteins. CJD is the most common type of prion diseases with incidence of 1/100000 per year. In this study, we aimed to review clinical, laboratory, electrophysiological and radiological findings and prognosis of 21 cases with the diagnosis of CJD.Methods:A retrospective review of patient records in a single institution was performed to identify patients with sporadic CJD from 2010 to 2018. January 2017 diagnostic criteria were used for inclusion. In this study, 21 patients were included for analysis. Demographic features, symptoms, clinical findings of neurological examination, disease duration, laboratory findings, electrophysiological test results, findings of magnetic resonance imaging and prognosis were documented.Results:Twelve of the patients included in this study were male and nine were female. The mean age was 64.1 (49–79). All the patients had dementia and changes in personality at admission to the hospital. The duration of complaints was 5.4±4 months. Periodic sharp wave complexes were observed in the electroencephalogram at baseline or follow-up. Twenty patients had undergone lumbar puncture to identify 14.3.3 protein tests in cerebrospinal fluid. In six of twelve patients whose results were received, 14.3.3 protein level was positive, whereas four of them were negative and two were at borderline. Seven patients died of the disease during the follow-up in our hospital within 2.8 (1–6) months from the symptom onset.Conclusion:In patients with rapidly progressive dementia, behavioral changes, hallucinations and myoclonus, CJD should be kept in mind for earlier diagnosis

Impact of non-pharmaceutical interventions on circulating respiratory viruses during the COVID-19 pandemic in Turkey

BACKGROUND: Non-pharmaceutical interventions (NPIs) applied to limit the SARS-CoV-2 pandemic also affect the circulation and seasonal characteristics of other respiratory viruses. OBJECTIVES: Assess the impact of NPIs on the spread and seasonal characteristics of non-SARS-CoV-2 respiratory viruses and examine viral respiratory co-infections. DESIGN: Retrospective cohort SETTING: Single center in Turkey. PATIENTS AND METHODS: Syndromic multiplex viral polymerase chain reaction (mPCR) panel results of patients admitted to the Ankara Bilkent City Hospital with symptoms of acute respiratory tract infection between April 1, 2020 and October 30, 2022 were evaluated. Two study periods before and after 1 July 2021, when the restrictions were discontinued, were statistically analyzed and compared to determine the effect of NPIs on circulating respiratory viruses. MAIN OUTCOME MEASURES: Prevalence of respiratory viruses as determined by syndromic mPCR panel. SAMPLE SIZE: 11300 patient samples were evaluated. RESULTS: At least one respiratory tract virus was detected in 6250 (55.3%) patients. Of these, at least one respiratory virus was detected in 5% in the first period (between April 1, 2020 and June 30, 2021, when NPIs were applied), and in 95% in the second period (between July 1, 2021 and October 30, 2022, when NPIs were relaxed). After the removal of NPIs, there was a statistically significant increase in hRV/EV, RSV-A/B, Flu A/H3, hBoV, hMPV, PIV-1, PIV-4, hCoV-OC43, PIV-2 and hCoV-NL63 (P<.05). In the 2020-2021 season, when strict NPIs were applied, all respiratory viruses evaluated did not have the usual seasonal peak and there were no seasonal influenza epidemics during this period. CONCLUSIONS: NPIs resulted in a dramatic decrease in the prevalence of respiratory viruses and notable disruption of seasonal characteristics. LIMITATIONS: Single-center study and retrospective. CONFLICT OF INTEREST: None

Common mistakes in the dual-energy x-ray absorptiometry (dxa) in turkey. A retrospective descriptive multicenter study

Background: Osteoporosis is a widespread metabolic bone disease representing a global public health problem currently affecting more than two hundred million people worldwide. The World Health Organization states that dual-energy X-ray absorptiometry (DXA) is the best densitometric technique for assessing bone mineral density (BMD). DXA provides an accurate diagnosis of osteoporosis, a good estimation of fracture risk, and is a useful tool for monitoring patients undergoing treatment. Common mistakes in BMD testing can be divided into four principal categories: 1) indication errors, 2) lack of quality control and calibration, 3) analysis and interpretation errors, and 4) inappropriate acquisition techniques. The aim of this retrospective multicenter descriptive study is to identify the common errors in the application of the DXA technique in Turkey. Methods: All DXA scans performed during the observation period were included in the study if the measurements of both, the lumbar spine and proximal femur were recorded. Forearm measurement, total body measurements, and measurements performed on children were excluded. Each examination was surveyed by 30 consultants from 20 different centers each informed and trained in the principles of and the standards for DXA scanning before the study. Results: A total of 3,212 DXA scan results from 20 different centers in 15 different Turkish cities were collected. The percentage of the discovered erroneous measurements varied from 10.5% to 65.5% in the lumbar spine and from 21.3% to 74.2% in the proximal femur. The overall error rate was found to be 31.8% (n = 1021) for the lumbar spine and 49.0% (n = 1576) for the proximal femur. Conclusion: In Turkey, DXA measurements of BMD have been in use for over 20 years, and examination processes continue to improve. There is no educational standard for operator training, and a lack of knowledge can lead to significant errors in the acquisition, analysis, and interpretation