10 research outputs found

    Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect.

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    Mortality due to opioid use has grown to the point where, for the first time in history, opioid-related deaths exceed those caused by car accidents in many states in the United States. Changes in the prescribing of opioids for pain and the illicit use of fentanyl (and derivatives) have contributed to the current epidemic. Less known is the impact of opioids on hippocampal neurogenesis, the functional manipulation of which may improve the deleterious effects of opioid use. We provide new insights into how the dysregulation of neurogenesis by opioids can modify learning and affect, mood and emotions, processes that have been well accepted to motivate addictive behaviours

    Imprints of Natural Phenomena and Human Activity Observed During 10 Years of ELF Magnetic Measurements at the Hylaty Geophysical Station in Poland

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    Current human activity produces strong electromagnetic pollution. The power spectrum in the extremely low frequency (ELF, 3-3000 Hz) range is mainly polluted by anthropogenic narrow spectral lines at 16.66, 50, and 60 Hz and their harmonics. Meanwhile, signatures connected with natural phenomena appearing in the Earth’s atmosphere, ionosphere and magnetosphere are also observed in the same frequency range

    Non-nociceptive roles of opioids in the CNS: opioids’ effects on neurogenesis, learning, memory and affect

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    Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary

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    Rearing on Hind Legs, Environmental Novelty, and the Hippocampal Formation

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    Genetic predispositions of Parkinson’s disease revealed in patient-derived brain cells

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    Pharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals

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    Realistic expectations of prepulse inhibition in translational models for schizophrenia research

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