The diagnostic values of ischemia-modified albumin in patients with acute abdominal pain and its role in differentiating acute abdomen

Aim. The aim of this study was to evaluate the diagnostic value of serum ischemia-modified albumin (IMA) levels in patients presenting to the emergency department with acute abdominal pain and its use in differentiating acute surgical abdomen. Methods. This single-center prospective cross-sectional study included 334 adult patients who presented to the emergency department. These consisted of 194 patients (Group 1) with nontraumatic abdominal pain commencing in the preceding week, who were definitely diagnosed and either hospitalized in a specific department or planned for discharge, and a control group of 140 patients (Group 2). Results. The mean IMA value of the patients diagnosed with acute appendicitis was statistically significantly higher than that of the control group. The mean IMA value of the patients diagnosed with acute appendicitis, ovarian pathologies, and gastritis-peptic ulcer was statistically significantly higher than that of the nonspecific abdominal pain group. Conclusion. Serum IMA levels can be used as a diagnostic marker in patients with acute appendicitis. Furthermore, serum IMA levels in patients presenting to the emergency department with abdominal pain may be indicative of patients requiring surgery or of complicated cases, particularly in terms of acute appendicitis and ovarian pathologies

Perfusion Index Analysis in Patients Presenting to the Emergency Department Due to Synthetic Cannabinoid Use

Background and Objectives: The perfusion index (PI) indicates the ratio of pulsatile blood flow in peripheral tissue to non-pulsatile blood flow. This study was performed to examine the blood perfusion status of tissues and organs of patients using synthetic cannabinoids (SCs). Materials and Methods: The records of patients aged 17 or over presenting to the adult emergency department due to SC use between 1 January 2016 and 31 December 2017 were examined in this single-center, retrospective, cross-sectional study. Examined factors included time from consumption of SC to presentation to the emergency department, as well as simultaneously determined systolic and diastolic blood pressures, heart rate (beats per min), Glasgow Coma Score (GCS), and PI values. Patients were divided into two groups, A and B, depending on the amount of time that had elapsed between SC consumption and presentation to the emergency department, and statistical data were compared. Results: The mean PI value in Group A was lower than that in Group B. Therefore, we concluded that peripheral tissue and organ blood perfusion is lower in the first 2 h following SC consumption than after 2 h. Systolic, diastolic, and mean arterial blood pressure and mean GCS values were also statistically significantly lower in Group A than in Group B. Conclusions: A decreased PI value may be an early sign of reduced-perfusion organ damage. PI is a practical and useful parameter in the early diagnosis of impaired organ perfusion and in monitoring tissue hypoxia leading to organ failure

Acil serviste ateşin nadir bir nedeni: anhidrotik ektodermal displazi

[Özet Yok

Clinical evaluation of synthetic cannabinoid users A pilot study in emergency department

Haseki Eğitim ve Araştırma Hastanesi acil servisine sentetik kanabinoid kullanımı şüphesi ile getirilen hastalarınklinik ve biyokimyasal durumlarını retrospektif olarak değerlendirmeyi amaçladık. Klinik değerlendirmelere göre, en çok etkilenen sistemlerintravma ile yaralanma dışında tüm vücudunyanı sıra kardiyovasküler, böbrek tutulumu, zihinsel / davranışsal ve hematolojik olduğu belirlenmiştir. Rabdomiyoliz ve ilgili böbrek yetmezliği, kalp hastalıkları ve solunumsal defektlerin ciddi prognozla kalıcı hasarlara neden olduğu bilinmektedir. Bu hastalar arasında görülen semptom ve teşhis varyasyonları muhtemelen sentetik kannabinoidlerin değişken kimyasal yapısından kaynaklandığı düşünülmektedir

Heart Attack in the Course of Lithium Overdose

Kalkan, Asim/0000-0002-5800-0201;WOS: 000392223900001PubMed: 27703795Introduction: Lithium overdose can be associated with cardiac toxicity, especially in those with underlying heart disease. Toxic levels of serum lithium are associated with cardiotoxic effects ranging from simple ECG disorders to dysrhythmias, cardiomyopathy and even acute myocardial infarction (AMI). This report describes a patient with AMI accompanied by high blood levels of lithium. Case Presentation: A 62-year-old woman was admitted to the emergency department due to weakness and acute chest pain. Her ECG revealed ST elevation in leads DI, aVL and V5-6, with a ventricular rate of 80 bpm. Blood chemistry and complete blood count were within normal limits. the patient's blood lithium level was measured as 2.3 mmol/L (N: 0.5-0.8 mmol/L), and her troponin I level was 0.892 ng/mL (N: 0-0.01 ng/mL). Coronary angiography produced normal findings, concurrent with the resolution of electrocardiographic abnormalities following elimination of lithium. the clinical course in the intensive care unit was uneventful and the patient was discharged on the seventh day. Conclusions: Lithium intoxication should be considered in the differential diagnosis, especially in elderly patients on lithium therapy who are admitted to the emergency department with chest pain

Near infrared spectrophotometry (cerebral oximetry) in predicting the return of spontaneous circulation in out-of-hospital cardiac arrest

WOS: 000328752500003PubMed: 24139953Aim: We assessed out-of-hospital cardiac arrest patients' cerebral oxygenation during cardiopulmonary resuscitation (CPR) using near infrared spectrophotometry (NIRS). We evaluated the relation between a rise in patients' cerebral saturation values between the start and end of CPR and return of spontaneous circulation. Materials and methods: Twenty-three patients with unwitnessed out-of-hospital cardiac arrest and brought to our emergency department by emergency ambulance were evaluated. Cerebral saturations from time of start of CPR were measured using NIRS. CPR was performed for a maximum of 30 min. the relation between cerebral saturations in patients with or without return of spontaneous circulation was then evaluated. Results: Twenty-three patients, 12 (52.2%) female and 11 (47.8%) male, with a mean age of 64.09 +/- 13.66 were included. A correlation was determined between a rise in cerebral saturation measured throughout CPR and the return of spontaneous circulation (P < .001). Conclusion: Patients whose cerebral saturation values measured with NIRS rise during CPR have a higher post-resuscitation survival rate. Monitoring of patients during CPR with this non-invasive technique may be a good method for predicting return of spontaneous circulation. Published by Elsevier Inc

Demographic and clinical characteristics among Turkish homeless patients presenting to the emergency department

Objective: Since the homeless are at greater risk of encountering health problems than the general population, the reasons for and incidence of their presentations to emergency departments also vary. The purpose of this study was to determine the sociodemographic and clinical characteristics of Turkish homeless patients who brought to the emergency department by ambulance. Materials and methods: The records of homeless adult patients brought to the ED by 112 emergency service ambulance teams over a 1-year period from January to December, 2014, were examined retrospectively. Results: Thirty-six (21.56%) of the homeless patients enrolled in the study presented due to trauma, and 131 (78.44%) due to non-traumatic causes. One hundred thirty-seven (82.04%) of the total patient group were male. The mean age of the non-trauma patients was 47.3 ± 15.2 years (range, 18â81 years), and the mean age of the trauma patients was 36.9 ± 14.4 years (range, 18â63 years). The most common reason for presentation among patients presenting to the emergency department for non-trauma reasons was clouded consciousness (n = 39, 23.35%), followed by general impaired condition (n = 26, 15.57%), respiratory difficulty (n = 25 14.97%) and abdominal pain (n = 21, 12.57%). The most common reason for presentation among trauma cases was traffic accidents (n = 13, 7.78%), followed by sharp implement injury (n = 9, 5.39%). Four (2.4%) homeless patients died in the emergency department, three (%1.8) homeless patients discharged from the emergency department, and the remaining 160 (95.8%) were admitted to the hospital. Conclusion: Homeless patients may present to the emergency department due to traumatic or non-traumatic causes. Admission levels are high among these patients, who may have many acute and chronic problems, and appropriate precautions must be taken in the management of these subjects in the emergency department. Keywords: Homelessness, Homeless patient, Emergency department visit, Demographic

Diagnostic Value of Signal Peptide, CUB (Complement C1r/C1s, Uegf, and Bmp1), EGF (Epidermal Growth Factor)-Like Domain-Containing Protein 1 (SCUBE1) and Chemerin in Experimental Testicular Torsion

Aim: The purpose of this experimental study was to investigate the potential diagnostic value of the platelet activation marker SCUBE1 [signal peptide, CUB (complement C1r/C1s, Uegf, and Bmp1), and EGF (epidermal growth factor)-like domain-containing protein 1] and the adipocytokine chemerin in a prepubertal rat model of testicular torsion (TT)

The Diagnostic Value of Irisin and Visfatin in Experimental Testicular Torsion

Aim: Testicular torsion (TT) is one of the most important causes of acute scrotum in children and young men. Very scarce number of serum laboratory parameters might be used in the early diagnosis of patients with TT. We planned this study in consideration of the possible significance of the changes in serum irisin and visfatin levels in the diagnosis of TT. Methods: We used 28 rats in four groups. In the control group, blood samples and specimens of testicular tissue were collected at 2nd and 4th hours after torsion. In the torsion groups, the left testis was twisted, and blood samples and specimens of the testicular tissue were collected at the 2nd and 4th hours for analysis. Results: There was no statistically significant difference in mean irisin and visfatin levels at the 2nd and 4th hours between rats with TT and controls. There was no statistically difference between mean irisin and vistatin levels at the 2nd hour and at the 4th hour in torsion and control groups. Conclusion: In our experimental TT method, we could not find a statistically significant difference between serum levels of irisin and visfatin. We assume that further studies are needed on this issue