A Case of Fatal Congenital Human Immunodeficiency Virus Infection

Acquired immune deficiency syndrome is a clinical condition caused by human immunodeficiency virus (HIV) which can be transmitted either vertically or horizontally. More than 90% of children living with HIV in developing countries have been infected through mother to child transmission during pregnancy, around the time of birth, or through breastfeeding. In order to reduce the number of infected children, increasing emphasis should be placed on preventing mother to child transmission programs with the use of antiretroviral medications in the pregnant woman during pregnancy and at delivery and, starting immediately after birth for the exposed infant. Here, we present the case of a 60-day-old infant heavily immunocompromised due to an extremely high viral burden of HIV, which was acquired perinatally from an undiagnosed and untreated mother, leading to severe bronchopneumonia, sepsis, septic shock and death

Zinc, copper, and selenium levels in babies with congenital heart disease

Introduction: Although the etiology of congenital heart disease is uncertain, interaction of genetic and environmental factors has been implicated in 90% of cases. The purpose of this study was to investigate the relationships between serum zinc. copper. and selenium levels and congenital heart disease. Materials and methods: Zinc, copper, and selenium levels were investigated in 44 patients (22 female, 22 male) diagnosed with congenital heart disease and their mothers, together with 32 healthy children (15 female and 17 male) in our healthy-child clinic and with no cardiac pathology at echocardiography, and their mothers. Results: Copper levels in patients with patent foramen ovate and zinc levels in patients with pulmonary stenosis were significantly lower than those in the subjects with no disease children (p = 0.039 and p = 0.023. respectively). However, no difference was determined in serum selenium levels between the patient and control groups in our study. No statistically significant difference was determined in these trace clement levels in mothers of children in the patient and control groups. Conclusion: In conclusion. our study is significant in showing an association between copper and zinc deficiency and congenital heart disease

Epidemiological, Clinical, and Laboratory Features of Children With COVID-19 in Turkey

Objectives: The aim of this study is to identify the epidemiological, clinical, and laboratory features of coronavirus disease 2019 (COVID-19) in children