22 research outputs found
Addendum: "The Dynamics of M15: Observations of the Velocity Dispersion Profile and Fokker-Planck Models" (ApJ, 481, 267 [1997])
It has recently come to our attention that there are axis scale errors in
three of the figures of Dull et al. (1997, hereafter D97). D97 presented
Fokker-Planck models for the collapsed-core globular cluster M15 that include a
dense, centrally concentrated population of neutron stars and massive white
dwarfs, but do not include a central black hole. In this Addendum, we present
corrected versions of Figures 9, 10, and 12, and an expanded version of Figure
6. This latter figure, which shows the full run of the velocity dispersion
profile, indicates that the D97 model predictions are in good agreement with
the moderately rising HST-STIS velocity dispersion profile for M15 reported by
Gerssen et al. (2002, astro-ph/0209315). Thus, a central black hole is not
required to fit the new STIS velocity measurements, provided that there is a
sufficient population of neutron stars and massive white dwarfs. This
conclusion is consistent with the findings of Gerssen et al. (2002,
astro-ph/0210158), based on a reapplication of their Jeans equation analysis
using the corrected mass-to-light profile (Figure 12) for the D97 models.Comment: 4 pages, 4 figures, submitted to Ap
International Network for Capacity Building for the Control of Emerging Viral Vector-Borne Zoonotic Diseases: Arbo-Zoonet
Arboviruses are arthropod-borne viruses, which include West Nile fever virus (WNFV), a mosquito-borne virus, Rift Valley fever virus (RVFV), a mosquito-borne virus, and Crimean-Congo haemorrhagic fever virus (CCHFV), a tick-borne virus. These arthropod-borne viruses can cause disease in different domestic and wild animals and in humans, posing a threat to public health because of their epidemic and zoonotic potential. In recent decades, the geographical distribution of these diseases has expanded. Outbreaks of WNF have already occurred in Europe, especially in the Mediterranean basin. Moreover, CCHF is endemic in many European countries and serious outbreaks have occurred, particularly in the Balkans, Turkey and Southern Federal Districts of Russia. In 2000, RVF was reported for the first time outside the African continent, with cases being confirmed in Saudi Arabia and Yemen. This spread was probably caused by ruminant trade and highlights that there is a threat of expansion of the virus into other parts of Asia and Europe. In the light of global warming and globalisation of trade and travel, public interest in emerging zoonotic diseases has increased. This is especially evident regarding the geographical spread of vector-borne diseases. A multi-disciplinary approach is now imperative, and groups need to collaborate in an integrated manner that includes vector control, vaccination programmes, improved therapy strategies, diagnostic tools and surveillance, public awareness, capacity building and improvement of infrastructure in endemic regions
The Global Kinematics of the Globular Cluster M15
We present velocities for 230 stars in the outer parts of the globular
cluster M15 measured with the Hydra multi-object spectrograph on the WIYN
telescope. A new Bayesian technique is used for analyzing the data. The mean
velocity of the cluster is -106.9+/- 0.3 km/s. Rotation with an amplitude of
1.5+/- 0.4 km/s and a position angle of 125+/-19 degrees is observed and the
model including rotation is marginally favored over one without rotation. The
velocity dispersion decreases from the center out to about 7' and then appears
to increase slightly. This behavior is strikingly different from the continued
decline of velocity dispersion with increasing radius that is expected in an
isolated cluster. We interpret this as an indication of heating of the outer
part of M15 by the Galactic tidal field.Comment: 32 pages, LaTeX, includes 13 eps figures, 5 tables are in external
tex files, to appear in Feb 1998 A
Rhinosinusitis derived Staphylococcal enterotoxin B plays a possible role in pathogenesis of food allergy
BACKGROUND: Staphylococcal enterotoxin B (SEB) is a potent immunomodulator and implicated with pathogenesis of inflammatory diseases mediated by Th1 or Th2 dominant immune responses. The objective of this study is to determine a possible association between rhinosinusitis derived SEB and pathogenesis of food allergy (FA). METHODS: The study included chronic rhinosinusitis (CRS) patients with FA (N = 46) or without FA (N = 33). Controls included FA patients without CRS (N = 26) and healthy volunteers (N = 25). In CRS patients, we assessed the parameters associated with FA including prick skin test (PST) reactivity to food allergens, serum levels of allergen-specific IgE and cytokines (IL-4, IL-13, IFN-Ă(3)), and the number/reactivity of food-allergen specific Th1/Th2 cells in the peripheral blood before and 2 months after sinus surgery. Changes of these parameters were evaluated in comparison with changes in SEB concentration in the sinus lavage and stool samples and also in vitro reactivity to SEB. In CRS patients with FA, we also assessed changes in reactivity to oral challenge of offending food before and after sinus surgery. RESULTS: Two months following sinus surgery, we observed statistically significant reduction in PST and oral challenge reactivity in CRS patients with FA in parallel to decrease in serum levels of Th2 cytokines (IL-4 and IL-13) and allergen specific IgE. Improvement of reactivity to food allergens was positively associated with decline in SEB concentrations in the sinus lavage and stool samples. In vitro study results also indicated a role of SEB in aggravation of Th2 skewed responses to food allergens. Such changes were not observed in CRS-non FA patients or control FA patients. CONCLUSION: The rhinosinusitis derived SEB plays a certain role in the pathogenesis of FA by augmenting and/or maintaining polarized Th2 responses. Removal of SEB-producing pathogens from the rhinosinuses may be beneficial for attenuating the FA symptoms in patients with CRS-FA