19 research outputs found
Advanced moderately differentiated neuroendocrine carcinoma of the rectum with favorable prognosis by postoperative chemoradiation
Rectal neuroendocrine carcinoma is rare with poor prognosis. We report herein a case of advanced moderately differentiated neuroendocrine carcinoma of the rectum with relatively favorable prognosis treated by postoperative adjuvant chemoradiation therapy. A 58-year-old Japanese female was referred and colonofiberscopy revealed an easy-bleeding irregular tumor in the lower rectum, which was pathologically diagnosed as a neuroendocrine carcinoma. Surgical treatment consisted of abdominoperineal resection and lymph node dissection. The tumor invaded deeply into perirectal tissues, and 9 of 11 lymph node metastases were observed. Immunohistochemically, chromogranin A showed diffuse and strong staining, and the MIB-1 labeling index was 18.3 ± 5.6, supporting the high proliferation of the tumor. Some nucleus of the tumor showed positive staining for p21/WAF1. A total dose of 46 Gy of radiotherapy was delivered with 800 mg of daily oral doxifluridine. At 5 years post-surgery, the patient demonstrated no clinical evidence of intrapelvic recurrence or distant metastases
Carcinoma in adenoma of the duodenal bulb accompanied by gastrointestinal stromal tumor (GIST) of the stomach
Impact of improved bottom hypoxia on zooplankton community in shallow eutrophic lake
We followed changes in the abundance of meso- and microzooplankton after an existing
bottom hypoxia improved by the introduction of water with high oxygen content into the
bottom. Mesozooplankton, calanoid copepod Acartia hudsonica showed ten
times higher abundance under high oxygen condition at the bottom than under control where
there was less oxygen at the bottom. On the other hand, during summer when
microzooplankton such as rotifers and small cyclopoid species Oithona
spp. were dominant, no difference in their distribution pattern and abundance was
observed. Results have suggested that oxygen concentration at the bottom is one important
factor determining the abundance and distribution of mesozooplankton even in local-scale
probably by providing bottom refuge, but not for microzoooplankton. Since spring season is
important for recruitment of many commercial fish juveniles, the distribution of oxygen in
the lake seems very important for the fish stock in the lake
Impact of improved bottom hypoxia on zooplankton community in shallow eutrophic lake
We followed changes in the abundance of meso- and microzooplankton after an existing
bottom hypoxia improved by the introduction of water with high oxygen content into the
bottom. Mesozooplankton, calanoid copepod Acartia hudsonica showed ten
times higher abundance under high oxygen condition at the bottom than under control where
there was less oxygen at the bottom. On the other hand, during summer when
microzooplankton such as rotifers and small cyclopoid species Oithona
spp. were dominant, no difference in their distribution pattern and abundance was
observed. Results have suggested that oxygen concentration at the bottom is one important
factor determining the abundance and distribution of mesozooplankton even in local-scale
probably by providing bottom refuge, but not for microzoooplankton. Since spring season is
important for recruitment of many commercial fish juveniles, the distribution of oxygen in
the lake seems very important for the fish stock in the lake