BRINZOLAMIDE-INDUCED EYE DISCHARGE: A RARE ENTITY

ABSTRACTA 62-year-old lady diagnosed to have normal tension glaucoma was receiving triple therapy of topical brinzolamide, timolol, and careprost. Postapplication of brinzolamide eye drops patient experienced mucoid eye discharge starting 10 minutes after application of eye drops and persistingfor ½ hr. Slit lamp examination findings did not reveal any signs of infection. She gave a history of mucoid discharge since the day she was started onbrinzolamide eye drops. There are only two case reports describing mucoid discharge following brinzolamide eye drops. Thus, we report a similarscenario in our patient. We report this case so as to avoid unnecessary suspicion of infection in such cases.Keywords: Glaucoma, mucoid, infection

Shear Bond Strengths between Three Different Yttria-Stabilized Zirconia Dental Materials and Veneering Ceramic and Their Susceptibility to Autoclave Induced Low-Temperature Degradation

A study was undertaken to evaluate the effect of artificial aging through steam and thermal treatment as influencing the shear bond strength between three different commercially available zirconia core materials, namely, Upcera, Ziecon, and Cercon, layered with VITA VM9 veneering ceramic using Universal Testing Machine. The mode of failure between zirconia and ceramic was further analyzed as adhesive, cohesive, or mixed using stereomicroscope. X-ray diffraction and SEM (scanning electron microscope) analysis were done to estimate the phase transformation (m-phase fraction) and surface grain size of zirconia particles, respectively. The purpose of this study was to simulate the clinical environment by artificial aging through steam and thermal treatment so as the clinical function and nature of the bond between zirconia and veneering material as in a clinical trial of 15 years could be evaluated

BILATERAL BLINDNESS DUE TO ANTI-TUBERCULAR TREATMENT: A RARE PRESENTATION

ABSTRACTEthambutol and isoniazid (INH) are antimicrobial agents used in the treatment of tuberculosis. Optic neuropathy is a well-recognized toxic effectof these drugs, usually manifesting as a decrease in visual acuity and deficits in color vision. This study presents the case of a 75-year-old malediagnosed of spinal tuberculosis, who developed irreversible bilateral optic neuropathy causing complete blindness induced by ethambutol and INH.Ophthalmologic examination revealed sluggish pupillary reactions and optic disc pallor in both eyes. Visual evoked potential and magnetic resonanceimaging brain complemented the confirmation of the diagnosis.Keywords: Ethambutol, Isoniazid, Optic neuritis, Tuberculosis

Classification system on the selection of number of implants and superstructure design on the basis available vertical restorative space and interforaminal distance for implant supported mandibular overdenture

Purpose: The rehabilitation of the edentulous mandible is a challenge due to various limiting factors, of which the available vertical restorative space (AVRS) has been well understood in the literature. However, other anatomic variations such as arch form, arch size, and also the interforaminal distance (IFD) (due to the presence of mandibular nerve) are influential in the selection of size and position of implants, and thereby the prosthetic design. Materials and Method: In the present study, 30 edentulous patients from a group of 300 edentulous patients, representing all the three jaw relations (Class I, II, and III) were evaluated for designing a classification that could help in a comprehensive treatment plan for the edentulous mandible. Dental panoramic radiographs of each individual with a trial or final prosthesis were made. The horizontal IFD and AVRS values were calculated. Results: One-way analysis of variance followed by post-hoc test (multiple comparison) and Bonferroni method having P < 0.05 as significant value showed an overall mean of 38.9 mm for horizontal distance and 13.69 mm for the AVRS in 30 edentulous patients. Conclusion: The results showed that in the majority of cases (90%) there is insufficient space to place a bar attachment supported by five implants for mandibular overdentures. This suggests that a universal treatment plan cannot be followed due to varying anatomic factors. Hence, it becomes imperative to have a set of clinical guidelines based on the AVRS and IFD, for the selection of implant number and type of attachment. The article proposes a simple classification system based on the AVRS and IFD for establishing guidelines in the treatment planning of the edentulous mandible, to aid in selection of implant size, number, and position along with the associated prosthetic design